4503.T

Strong BuyUnloved QualityAI neutral

Astellas Pharma Inc. · Healthcare · Japan · $26.9B

JPY 2,243.5 +0.4% · close 6 Oct · scored 7 Oct

Unloved Quality: Strong and cheap; the market has not turned yet.

97
StockRank
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Quality
80
Value
77
Momentum
48

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P/E (TTM)
13.8x
peers 15.7x
ROE
21.3%
peers 8.3%
D/E
0.3x
peers 0.2x
Dividend %
3.4%
trailing yield
AI screening note

Astellas Pharma is a major Japanese biopharmaceutical company with key global commercial franchises in oncology and urology. While long-term cash flow generation remains intact, recent downward consensus revisions to near-term earnings reflect near-term loss-of-exclusivity challenges for legacy therapies and launch costs for newer pipeline assets.

ABOUT ASTELLAS PHARMA INC.

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Astellas Pharma Inc. is a major Japanese pharmaceutical company dedicated to the research, development, manufacturing, and marketing of innovative prescription drugs in therapeutic areas such as oncology, urology, and immunology. The company's competitive moat is built on a robust R&D pipeline focused on breakthrough therapies and a global commercial footprint. Astellas is a leading global pharmaceutical firm, committed to scientific innovation to address critical unmet medical needs.

FINANCIAL SUMMARY (JPY)

Year20222023202420252026CAGRTTM2027E2028EFwd CAGR
Revenue—1.5T1.6T1.9T2.1T12.1%2.3T2.3T2.2T1.2%
EPS (JPY)67.0854.249.5128.35162.7724.8%162.81169.04160.65-0.7%
Shares—1.8B1.8B1.8B1.8B-0.3%1.8B———
Debt—125.0B920.0B831.4B566.0B65.4%591.7B———
Equity—1.5T1.6T1.5T1.8T6.6%————
Op CF—327.8B172.5B194.5B560.2B19.6%593.7B———
Inv CF—-84.5B-845.8B-89.4B-66.7B—————
Fin CF—-195.6B614.1B-261.4B-404.8B—————
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PRICE (1Y) · JPY-6.6%
2,2102,2662,3222,3782,43520 Aug11 Sep6 Oct
SMA 50SMA 200

Price checkExperimental
SwingsCalm

Calmer than 73% of stocks we rank over the past year (30% a year).

How this is worked out

What it measures: day-to-day price moves over the past year, as a yearly figure, ranked against every stock we cover. Very calm under 20% a year, Calm 20 to 30%, Average 30 to 40%, Bumpy 40 to 55%, Very bumpy above that.

What we found: across about 13,500 stocks in 34 markets (2002 to 2025), past swings were a good guide to the next year's, and bumpier stocks fell further. How much further changed too much between eras to put a number on it.

Calm is not safe: a calm stock can still slide steadily.

Rules fixed before any data was fetched. Describes the chart, not a recommendation.

Close
JPY 2,243.5
RSI (14)
55.2
52-Week Range-16.0% from high
Low JPY 1,508.15High JPY 2,670.83

SCORE BREAKDOWN

Quality
80
ROIC
16.6%86.0
ROE
21.3%89.7
GP/Assets
51.5%88.1
Op. Margin
28.9%91.5
FCF/Assets
13.3%91.9
Piotroski
894.3
Int. Cover
27.8x74.6
D/E Ratio
0.30x41.0
Current Ratio
1.20x16.7
Value
77
P/E (TTM)
13.8x76.2
EV/EBITDA
6.5x85.2
P/FCF
8.9x86.0
P/B
2.1x59.2
P/S
1.8x70.6
Div Yield
3.4%74.2
Momentum
48
52W High %
84%75.2
RS 6M
-48%22.0
SMA 50/200
1.01x59.2
EPS Rev 4W
-0.9%26.6
EPS Rev 12W
+2.4%72.5
EPS Improve
-53%9.2
Q Growth
107%84.5

FUNDAMENTALS

Market Cap
$26.9B
P/E (Forward)
29.6x
Gross Margin
80.8%

SECTOR PEERS

Closest peers in Healthcare, ranked by industry match, size, and score similarity. Cross-listings of 4503.T are excluded.

TickerCompanyMkt CapStockRankSignal
4503.TAstellas Pharma Inc.(you)$26.9B97Strong Buy
4578.TOtsuka Holdings Co., Ltd.$36.6B91Strong Buy
4528.TOno Pharmaceutical Co., Ltd.$7.2B95Strong Buy
4536.TSanten Pharmaceutical Co., Ltd.$3.5B95Strong Buy
4568.TDaiichi Sankyo Company, Limited$33.3B52Hold
4519.TChugai Pharmaceutical Co., Ltd.$69.4B66Buy
7741N.MXHOYA Corporation$47.0B96Strong Buy
4543.TTerumo Corporation$21.2B81Strong Buy
7733.TOlympus Corporation$13.5B82Strong Buy
6869.TSysmex Corporation$7.1B91Strong Buy

Peer medians: ROE 8.3% · P/E 15.7x · Gross margin 47.0%

Company Deep Dive

Business segments breakdown, earnings transcript analysis, management credibility scoring, competitive landscape, and scenario modelling.

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Astellas Pharma Inc. (4503.T): Stock Score Summary

Astellas Pharma Inc. (4503.T) has a MoatMap StockRank of 97/100 based on Quality (80/100), Value (77/100), and Momentum (48/100) factor scores. The current signal is STRONG BUY. Astellas Pharma is a major Japanese biopharmaceutical company with key global commercial franchises in oncology and urology. While long-term cash flow generation remains intact, recent downward consensus revisions to near-term earnings reflect near-term loss-of-exclusivity challenges for legacy therapies and launch costs for newer pipeline assets.

Astellas Pharma Inc. is a major Japanese pharmaceutical company dedicated to the research, development, manufacturing, and marketing of innovative prescription drugs in therapeutic areas such as oncology, urology, and immunology. The company's competitive moat is built on a robust R&D pipeline focused on breakthrough therapies and a global commercial footprint. Astellas is a leading global pharmaceutical firm, committed to scientific innovation to address critical unmet medical needs.

Key Financial Metrics

PriceJPY 2,243.5
Market Cap$26.9B
P/E (TTM)13.83
P/E (Forward)29.63
Price/Book2.07
Return on Equity21.3%
Return on Invested Capital16.6%
Debt/Equity0.30x
Gross Margin80.8%
Operating Margin28.9%
Revenue Growth26.7%
Dividend Yield3.4%
Free Cash Flow$3.0B

Astellas Pharma Inc. operates in the Drug Manufacturers - General industry, part of the Healthcare sector (Japan).

Frequently Asked Questions

What is Astellas Pharma Inc.’s (4503.T) StockRank?
MoatMap’s StockRank for Astellas Pharma Inc. (4503.T) is 97/100, with a Strong Buy signal. It is a composite of Quality (80), Value (77), and Momentum (48) factor ranks across MoatMap’s universe of 24,000+ stocks.
Does Astellas Pharma Inc. have an economic moat?
Astellas Pharma Inc. (4503.T) has a Quality factor score of 80/100. The Quality factor combines ROIC, Piotroski F-Score, and leverage: the financial fingerprints of a durable competitive advantage. A Quality score above 70 typically indicates a company with the characteristics of a moated business.
Is Astellas Pharma Inc. a buy, hold, or sell?
MoatMap’s current signal for Astellas Pharma Inc. (4503.T) is Strong Buy, based on a StockRank of 97/100. Signals are derived mechanically from the StockRank composite and should be one input among many; combine with your own thesis on management, competitive position, and valuation.
What sector is Astellas Pharma Inc. in?
Astellas Pharma Inc. (4503.T) operates in the Healthcare sector, specifically the Drug Manufacturers - General industry (Japan).