ANRO

SellSinker

Alto Neuroscience, Inc. · Healthcare · United States · $862M cap · $14.9M/day traded

$22.11 +0.6% · close 26 Oct · scored 27 Oct

StockRank up 3.9 since 24 Oct: Momentum up 6.

Sinker: Weak, expensive and falling. Nothing here to keep it afloat.

22
StockRank
Get score and insider alerts
Quality
28
Value
27
Momentum
50

As of 27 Oct 2026, MoatMap's StockRank for Alto Neuroscience, Inc. (ANRO) is 22/100, ranked against 24,000+ stocks in 35 markets (Quality 28, Value 27, Momentum 50, each scored against its sector).

Does StockRank work? Each month we publish how every decile did, whichever way it went. See the record →

P/E (TTM)
—
peers 27.2x
ROE
-49.2%
peers -30.1%
D/E
0.1x
peers 0.2x
Dividend %
—
trailing yield

ABOUT ALTO NEUROSCIENCE, INC.

Read

Alto Neuroscience, Inc. is a clinical-stage biopharmaceutical company pioneering precision psychiatry through its proprietary Precision Psychiatry Platform. The company's competitive moat is built on its AI-driven analysis of brain biomarkers, EEG, and behavioral data to match patients with targeted drug candidates. It operates as a niche innovator aiming to revolutionize treatment for depression and other mental health conditions.

FINANCIAL SUMMARY (USD)

Year2022202320242025CAGRTTM2026E2027EFwd CAGR
Revenue0000—————
EPS-2.13-1.42-2.50-2.19—-2.31-2.92-3.19—
Shares25.6M25.6M27.0M31.9M+24.8%39.2M———
Debt9.7M10.0M16.9M24.0M35.0%23.3M———
Equity-38.4M-71.7M151.5M151.1M-0.2%————
Op CF-20.4M-33.4M-47.4M-51.8M—-68.3M———
Inv CF-0.7M-0.5M-2.1M-24.0K—————
Fin CF43.8M68.1M135.7M60.1M—————
Loading 1Y...
PRICE (1Y) · USD-26.9%
21.724.026.328.731.015 Sep6 Oct26 Oct
SMA 50SMA 200

Price checkNo clear trendExperimental

No clear trend: not near its 52-week low, and not in a steady uptrend.

SwingsVery bumpy

Swung more than 88% of stocks we rank over the past year (79% a year).

How this is worked out

StockRank judges the business. The price check reads only the chart: it is the price side of the Momentum score, in words.

The rules: Still falling is a new 52-week low in the last two weeks, at least 25% below the high. Finding a floor is no new low since. Turning up is 20 or more trading days without a new low, at least 10% off it, and back above a rising 50-day average. In an uptrend is above the 200-day average and within 15% of the high.

In 2,112 US drawdowns since 2001, buying while the price was still falling was followed by a further 20% drop 42% of the time. Waiting for a turn like this one cut that to 33%, at about 7% higher prices and with no better returns. Part of that cut is simply not buying: 13% of falls never turned, and waiting kept those out. Among turns that were bought, 38% still fell another 20%, and 33% of turns were followed by a new low within six months. The benefit was largest in crashes such as 2008 and 2020.

What it measures: day-to-day price moves over the past year, as a yearly figure, ranked against every stock we cover. Very calm under 20% a year, Calm 20 to 30%, Average 30 to 40%, Bumpy 40 to 55%, Very bumpy above that.

What we found: across about 13,500 stocks in 34 markets (2002 to 2025), past swings were a good guide to the next year's, and bumpier stocks fell further. How much further changed too much between eras to put a number on it.

Calm is not safe: a calm stock can still slide steadily.

Rules fixed before any data was fetched. Describes the chart, not a recommendation.

Close
$22.11
RSI (14)
42.3
52-Week Range-41.0% from high
Low $10.20High $37.48

SCORE BREAKDOWN

Quality
28
ROIC
-41.5%18.8
ROE
-49.2%18.3
GP/Assets
—N/A
Op. Margin
0.0%38.6
FCF/Assets
-34.0%13.1
Piotroski
29.2
Int. Cover
-29.8x15.1
D/E Ratio
0.11x61.4
Current Ratio
14.85x92.8
Value
27
P/E (TTM)
—N/A
EV/EBITDA
-7.3x25.0
P/FCF
—N/A
P/B
3.5x36.5
P/S
—N/A
Div Yield
—N/A
Momentum
50
52W High %
59%38.8
RS 6M
-16%43.4
SMA 50/200
1.21x89.3
EPS Rev 4W
+3.0%92.1
EPS Rev 12W
+7.2%80.9
EPS Improve
-38%11.1
Q Growth
—N/A

FUNDAMENTALS

Market Cap
$862M
P/E (Forward)
-6.9x
Gross Margin
—

SECTOR PEERS

Closest peers in Healthcare, ranked by industry match, size, and score similarity. Cross-listings of ANRO are excluded.

TickerCompanyMkt CapStockRankSignal
ANROAlto Neuroscience, Inc.(you)$862M22Sell
APMDApnimed, Inc.$791M23Sell
VSTMVerastem, Inc.$909M24Sell
GERNGeron Corporation$720M19Strong Sell
SLDBSolid Biosciences Inc.$635M21Sell
REPLReplimune Group, Inc.$1.1B24Sell
CGEMCullinan Therapeutics, Inc.$883M28Sell
SGPSpyGlass Pharma, Inc.$953M17Strong Sell
JANXJanux Therapeutics, Inc.$1.0B26Sell
ACHVAchieve Life Sciences, Inc.$669M19Strong Sell

Peer medians: ROE -30.1% · P/E 27.2x · Gross margin 63.3%

Company Deep Dive

Business segments breakdown, earnings transcript analysis, management credibility scoring, competitive landscape, and scenario modelling.

Request Deep Dive(50 Feathers)

Alto Neuroscience, Inc. (ANRO): Stock Score Summary

Alto Neuroscience, Inc. (ANRO) has a MoatMap StockRank of 22/100 based on Quality (28/100), Value (27/100), and Momentum (50/100) factor scores. The current signal is SELL.

Alto Neuroscience, Inc. is a clinical-stage biopharmaceutical company pioneering precision psychiatry through its proprietary Precision Psychiatry Platform. The company's competitive moat is built on its AI-driven analysis of brain biomarkers, EEG, and behavioral data to match patients with targeted drug candidates. It operates as a niche innovator aiming to revolutionize treatment for depression and other mental health conditions.

Key Financial Metrics

Price$22.11
Market Cap$862M
P/E (Forward)-6.90
Price/Book3.52
Return on Equity-49.2%
Return on Invested Capital-41.5%
Debt/Equity0.11x
Operating Margin0.0%
Free Cash Flow$-63M

Alto Neuroscience, Inc. operates in the Biotechnology industry, part of the Healthcare sector (United States).

Frequently Asked Questions

What is Alto Neuroscience, Inc.’s (ANRO) StockRank?
MoatMap’s StockRank for Alto Neuroscience, Inc. (ANRO) is 22/100, with a Sell signal. It is a composite of Quality (28), Value (27), and Momentum (50), each scored against its sector. The composite is then ranked across MoatMap’s universe of 24,000+ stocks.
Does Alto Neuroscience, Inc. have an economic moat?
Alto Neuroscience, Inc. (ANRO) has a Quality factor score of 28/100. The Quality factor combines ROIC, Piotroski F-Score, and leverage: the financial fingerprints of a durable competitive advantage. A Quality score above 70 typically indicates a company with the characteristics of a moated business.
Is Alto Neuroscience, Inc. a buy, hold, or sell?
MoatMap’s current signal for Alto Neuroscience, Inc. (ANRO) is Sell, based on a StockRank of 22/100. Signals are derived mechanically from the StockRank composite and should be one input among many; combine with your own thesis on management, competitive position, and valuation.
What sector is Alto Neuroscience, Inc. in?
Alto Neuroscience, Inc. (ANRO) operates in the Healthcare sector, specifically the Biotechnology industry (United States).