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DNLI

SELL

Denali Therapeutics Inc. · Healthcare · United States · $3.7B · Avg Vol: $46M/d

26
StockRank
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Q
28
V
27
M
60
P/E (TTM)
ROE
-49.6%
D/E
0.0x
Dividend %

COMPANY DESCRIPTION

Denali Therapeutics Inc. is a clinical-stage biotechnology company dedicated to developing therapies for neurodegenerative diseases such as Alzheimer's, Parkinson's, and ALS. Its competitive advantage lies in its proprietary scientific platforms, including its "Transport Vehicle" technology designed to enable drugs to cross the blood-brain barrier effectively. The company maintains a focused pipeline and strategic partnerships, positioning itself as a leader in addressing challenging neurological conditions.

FINANCIAL SUMMARY (USD)

Year2022202320242025CAGRTTM2026E2027EFwd CAGR
Revenue108.5M330.5M00204.7%34.0M103.7M-25.2%
EPS-2.60-1.06-2.57-2.97-2.83-2.37-2.53
Shares136.0M138.4M144.2M156.2M+14.9%158.7M
Debt60.4M52.2M48.7M36.8M-15.2%40.0M
Equity1.0B1.0B1.2B1.0B-0.9%
Op CF-244.7M-358.0M-347.7M-412.6M-412.3M
Inv CF-141.4M249.3M-88.8M255.3M
Fin CF310.7M17.8M484.3M189.2M
Loading 1Y...
PRICE (1Y)+8.8%
21.6623.0524.4325.8227.21Jun 12Jul 7Jul 27
SMA 50SMA 200
Close
$23.57
RSI (14)
37.3
52W High
$27.30
From 52W High
0.9%

SCORE BREAKDOWN

Quality
28
ROIC
-53.1%14.3
ROE
-49.6%18.8
GP/Assets
-35.5%2.5
Op. Margin
0.0%41.3
FCF/Assets
-16.6%22.1
Piotroski
321.7
Int. Cover
N/A
D/E Ratio
0.04x72.5
Current Ratio
9.29x85.0
Value
27
P/E (TTM)
N/A
EV/EBITDA
-5.1x25.0
P/FCF
N/A
P/B
3.9x34.7
P/S
N/A
Div Yield
N/A
Momentum
60
52W High %
86%80.1
RS 6M
9%79.7
SMA 50/200
1.14x85.4
EPS Rev 4W
-1.4%20.5
EPS Rev 12W
+2.7%73.3
EPS Improve
+11%28.9
Q Growth
N/A

FUNDAMENTALS

Market Cap
$3.7B
P/E (Forward)
-9.1x
Gross Margin
0.0%

SECTOR PEERS

Closest peers in Healthcare, ranked by industry match, size, and score similarity. Cross-listings of DNLI are excluded.

TickerCompanyMkt CapStockRankSignal
DNLIDenali Therapeutics Inc.(you)$3.7B26SELL
ALMSAlumis Inc.$3.6B22SELL
RCUSArcus Biosciences, Inc.$3.6B22SELL
LEGNLegend Biotech Corporation$4.3B24SELL
CAICaris Life Sciences, Inc.$4.4B27SELL
IDYAIDEAYA Biosciences, Inc.$3.4B29SELL
VKTXViking Therapeutics, Inc.$4.0B21SELL
RAREUltragenyx Pharmaceutical Inc.$2.6B26SELL
TNGXTango Therapeutics, Inc.$4.3B29SELL
CLDXCelldex Therapeutics, Inc.$2.8B24SELL

Peer medians: ROE -25.5% · P/E 27.6x · Gross margin 50.6%

Denali Therapeutics Inc. (DNLI) — Stock Score Summary

Denali Therapeutics Inc. (DNLI) has a MoatMap StockRank of 26/100 based on Quality (28/100), Value (27/100), and Momentum (60/100) factor scores. The current signal is SELL.

Denali Therapeutics Inc. is a clinical-stage biotechnology company dedicated to developing therapies for neurodegenerative diseases such as Alzheimer's, Parkinson's, and ALS. Its competitive advantage lies in its proprietary scientific platforms, including its "Transport Vehicle" technology designed to enable drugs to cross the blood-brain barrier effectively. The company maintains a focused pipeline and strategic partnerships, positioning itself as a leader in addressing challenging neurological conditions.

Key Financial Metrics

Price$23.57
Market Cap$3.7B
P/E (Forward)-9.11
Price/Book3.92
Return on Equity-49.6%
Return on Invested Capital-53.1%
Debt/Equity0.04x
Gross Margin0.0%
Operating Margin0.0%
Free Cash Flow$-190M

Denali Therapeutics Inc. operates in the Biotechnology industry, part of the Healthcare sector (United States).

Frequently Asked Questions

What is Denali Therapeutics Inc.’s (DNLI) StockRank?
MoatMap’s StockRank for Denali Therapeutics Inc. (DNLI) is 26/100, with a Sell signal. It is a composite of Quality (28), Value (27), and Momentum (60) factor ranks across MoatMap’s 20,000+ stock universe.
Does Denali Therapeutics Inc. have an economic moat?
Denali Therapeutics Inc. (DNLI) has a Quality factor score of 28/100. The Quality factor combines ROIC, Piotroski F-Score, and leverage — the financial fingerprints of a durable competitive advantage. A Quality score above 70 typically indicates a company with the characteristics of a moated business.
Is Denali Therapeutics Inc. a buy, hold, or sell?
MoatMap’s current signal for Denali Therapeutics Inc. (DNLI) is Sell, based on a StockRank of 26/100. Signals are derived mechanically from the StockRank composite and should be one input among many — combine with your own thesis on management, competitive position, and valuation.
What sector is Denali Therapeutics Inc. in?
Denali Therapeutics Inc. (DNLI) operates in the Healthcare sector, specifically the Biotechnology industry (United States).