ILMN

BuyPremium GrowerAI neutral

Illumina, Inc. · Healthcare · United States · $40.7B cap · $1.0B/day traded

$288.79 +3.3% · close 28 Oct · scored 29 Oct

Premium Grower: Strong business with the market behind it, priced at a premium.

76
StockRank
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Report expected 29 Oct: the next-year EPS estimate has risen 3.3% over the last 14 weeks, up 3 weeks running.

Quality
78
Value
19
Momentum
74

As of 29 Oct 2026, MoatMap's StockRank for Illumina, Inc. (ILMN) is 76/100, ranked against 24,000+ stocks in 35 markets (Quality 78, Value 19, Momentum 74, each scored against its sector).

Does StockRank work? Each month we publish how every decile did, whichever way it went. See the record →

P/E (TTM)
50.3x
peers 27.2x
ROE
32.3%
peers -30.5%
D/E
0.9x
peers 0.2x
Dividend %
—
trailing yield
AI CONVICTION THESIS

Illumina is the dominant supplier of DNA sequencing instruments and consumables, with a large installed base that generates recurring consumables revenue. The shares are up about 133% this year to 52-week highs on recovering demand and hopes for Medicare coverage of multi-cancer detection tests. After that rally the valuation looks stretched, and insiders have sold about 1.4% of shares outstanding in the past 90 days, a large amount that tempers the bullish momentum.

ABOUT ILLUMINA, INC.

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Illumina, Inc. is the global leader in developing, manufacturing, and marketing integrated systems for large-scale analysis of genetic variation and function, providing sequencing and array-based instruments, reagents, and services. The company's formidable competitive moat stems from its proprietary sequencing technology, superior data quality, and extensive patent portfolio, which have established its platforms as the industry standard for genomic research and clinical applications worldwide. This dominant market position makes Illumina essential to advancements in precision medicine and biotechnology.

FINANCIAL SUMMARY (USD)

Year2022202320242025CAGRTTM2026E2027EFwd CAGR
Revenue4.6B4.5B4.4B4.3B-1.8%4.5B4.6B4.9B6.5%
EPS-28.00-7.34-7.695.47—5.366.056.9312.5%
Shares158.0M159.0M159.0M153.0M-3.2%151.0M———
Debt3.6B2.3B2.6B2.6B-10.4%2.5B———
Equity6.6B5.7B2.4B2.7B-25.6%————
Op CF392.0M478.0M837.0M1.1B40.1%1.1B———
Inv CF-591.0M-231.0M-178.0M-55.0M—————
Fin CF1.0B-1.2B-570.0M-744.0M—————
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PRICE (1Y) · USD+17.8%
23925326628029417 Sep8 Oct28 Oct
SMA 50SMA 200

Price checkIn an uptrendExperimental

Above its 200-day average and 7% below its 52-week high.

SwingsBumpy

Swung more than 63% of stocks we rank over the past year (50% a year).

How this is worked out

StockRank judges the business. The price check reads only the chart: it is the price side of the Momentum score, in words.

The rules: Still falling is a new 52-week low in the last two weeks, at least 25% below the high. Finding a floor is no new low since. Turning up is 20 or more trading days without a new low, at least 10% off it, and back above a rising 50-day average. In an uptrend is above the 200-day average and within 15% of the high.

In 2,112 US drawdowns since 2001, buying while the price was still falling was followed by a further 20% drop 42% of the time. Waiting for a turn like this one cut that to 33%, at about 7% higher prices and with no better returns. Part of that cut is simply not buying: 13% of falls never turned, and waiting kept those out. Among turns that were bought, 38% still fell another 20%, and 33% of turns were followed by a new low within six months. The benefit was largest in crashes such as 2008 and 2020.

What it measures: day-to-day price moves over the past year, as a yearly figure, ranked against every stock we cover. Very calm under 20% a year, Calm 20 to 30%, Average 30 to 40%, Bumpy 40 to 55%, Very bumpy above that.

What we found: across about 13,500 stocks in 34 markets (2002 to 2025), past swings were a good guide to the next year's, and bumpier stocks fell further. How much further changed too much between eras to put a number on it.

Calm is not safe: a calm stock can still slide steadily.

Rules fixed before any data was fetched. Describes the chart, not a recommendation.

Close
$288.79
RSI (14)
64.5
52-Week Range-6.6% from high
Low $94.00High $309.35

SCORE BREAKDOWN

Quality
78
ROIC
23.5%93.1
ROE
32.3%95.1
GP/Assets
46.0%84.5
Op. Margin
21.1%84.8
FCF/Assets
12.7%90.8
Piotroski
894.3
Int. Cover
11.8x64.3
D/E Ratio
0.89x16.3
Current Ratio
1.80x35.2
Value
19
P/E (TTM)
50.3x20.4
EV/EBITDA
36.4x15.5
P/FCF
48.1x26.6
P/B
14.3x7.0
P/S
9.1x25.5
Div Yield
—N/A
Momentum
74
52W High %
93%89.1
RS 6M
131%97.9
SMA 50/200
1.41x96.9
EPS Rev 4W
+0.4%74.9
EPS Rev 12W
+3.3%74.7
EPS Improve
+14%30.6
Q Growth
-12%27.6

FUNDAMENTALS

Market Cap
$40.7B
P/E (Forward)
44.0x
Gross Margin
67.9%

SECTOR PEERS

Closest peers in Healthcare, ranked by industry match, size, and score similarity. Cross-listings of ILMN are excluded.

TickerCompanyMkt CapStockRankSignal
ILMNIllumina, Inc.(you)$40.7B76Buy
AAgilent Technologies, Inc.$48.8B72Buy
IQVIQVIA Holdings Inc.$46.0B69Buy
WATWaters Corporation$44.5B66Buy
IDXXIDEXX Laboratories, Inc.$44.1B65Hold
LHLabcorp Holdings Inc.$26.7B83Strong Buy
DGXQuest Diagnostics Incorporated$26.7B83Strong Buy
RVTYRevvity, Inc.$17.7B65Buy
MEDPMedpace Holdings, Inc.$18.7B90Strong Buy
CRLCharles River Laboratories International, Inc.$16.6B62Hold

Peer medians: ROE -30.5% · P/E 27.2x · Gross margin 63.3%

Company Deep Dive

Business segments breakdown, earnings transcript analysis, management credibility scoring, competitive landscape, and scenario modelling.

Request Deep Dive(50 Feathers)

Illumina, Inc. (ILMN): Stock Score Summary

Illumina, Inc. (ILMN) has a MoatMap StockRank of 76/100 based on Quality (78/100), Value (19/100), and Momentum (74/100) factor scores. The current signal is BUY. Illumina is the dominant supplier of DNA sequencing instruments and consumables, with a large installed base that generates recurring consumables revenue. The shares are up about 133% this year to 52-week highs on recovering demand and hopes for Medicare coverage of multi-cancer detection tests. After that rally the valuation looks stretched, and insiders have sold about 1.4% of shares outstanding in the past 90 days, a large amount that tempers the bullish momentum.

Illumina, Inc. is the global leader in developing, manufacturing, and marketing integrated systems for large-scale analysis of genetic variation and function, providing sequencing and array-based instruments, reagents, and services. The company's formidable competitive moat stems from its proprietary sequencing technology, superior data quality, and extensive patent portfolio, which have established its platforms as the industry standard for genomic research and clinical applications worldwide. This dominant market position makes Illumina essential to advancements in precision medicine and biotechnology.

Key Financial Metrics

Price$288.79
Market Cap$40.7B
P/E (TTM)50.26
P/E (Forward)43.97
Price/Book14.33
Return on Equity32.3%
Return on Invested Capital23.5%
Debt/Equity0.89x
Gross Margin67.9%
Operating Margin21.1%
Revenue Growth9.4%
Free Cash Flow$846M

Illumina, Inc. operates in the Diagnostics & Research industry, part of the Healthcare sector (United States).

Frequently Asked Questions

What is Illumina, Inc.’s (ILMN) StockRank?
MoatMap’s StockRank for Illumina, Inc. (ILMN) is 76/100, with a Buy signal. It is a composite of Quality (78), Value (19), and Momentum (74), each scored against its sector. The composite is then ranked across MoatMap’s universe of 24,000+ stocks.
Does Illumina, Inc. have an economic moat?
Illumina, Inc. (ILMN) has a Quality factor score of 78/100. The Quality factor combines ROIC, Piotroski F-Score, and leverage: the financial fingerprints of a durable competitive advantage. A Quality score above 70 typically indicates a company with the characteristics of a moated business.
Is Illumina, Inc. a buy, hold, or sell?
MoatMap’s current signal for Illumina, Inc. (ILMN) is Buy, based on a StockRank of 76/100. Signals are derived mechanically from the StockRank composite and should be one input among many; combine with your own thesis on management, competitive position, and valuation.
What sector is Illumina, Inc. in?
Illumina, Inc. (ILMN) operates in the Healthcare sector, specifically the Diagnostics & Research industry (United States).