KNSA

BuyPremium GrowerAI neutral

Kiniksa Pharmaceuticals International, plc · Healthcare · United Kingdom · $6.0B cap · $46.3M/day traded

$76.73 -5.0% · close 23 Oct · scored 24 Oct

StockRank down 1.1 since 23 Oct.

Premium Grower: Strong business with the market behind it, priced at a premium.

79
StockRank
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Report expected 27 Oct: the next-year EPS estimate has fallen 4.3% over the last 14 weeks.

Quality
83
Value
17
Momentum
75

As of 24 Oct 2026, MoatMap's StockRank for Kiniksa Pharmaceuticals International, plc (KNSA) is 79/100, ranked against 24,000+ stocks in 35 markets (Quality 83, Value 17, Momentum 75, each scored against its sector).

Does StockRank work? Each month we publish how every decile did, whichever way it went. See the record →

P/E (TTM)
77.5x
peers 23.9x
ROE
14.0%
peers -5.5%
D/E
0.0x
peers 0.3x
Dividend %
—
trailing yield
AI CONVICTION THESIS

Kiniksa sells ARCALYST for recurrent pericarditis and raised its 2026 sales guidance after a strong second quarter, showing real demand and a profitable commercial franchise. The business depends almost entirely on one product, and the valuation already reflects that growth.

ABOUT KINIKSA PHARMACEUTICALS INTERNATIONAL, PLC

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Kiniksa Pharmaceuticals International, plc is a biopharmaceutical company dedicated to discovering, developing, and commercializing innovative therapeutics for patients with debilitating rare diseases. The company's strategic focus on underserved inflammatory and autoimmune conditions provides potential for orphan drug exclusivity, offering a strong competitive moat. Kiniksa aims to become a leader in developing targeted treatments for these specific, high-unmet-need patient populations.

FINANCIAL SUMMARY (USD)

Year20212022202320242025CAGRTTM2026E2027EFwd CAGR
Revenue—220.2M270.3M423.2M677.6M45.5%840.8M996.2M1.2B34.4%
EPS-2.302.640.20-0.600.80-32.8%0.991.25—56.3%
Shares—69.7M70.5M72.5M76.3M+9.5%————
Debt—5.9M12.3M9.9M9.5M17.1%8.9M———
Equity—396.1M438.8M438.4M567.6M12.7%————
Op CF—5.8M13.3M25.7M138.0M187.5%185.0M———
Inv CF—-8.1M-29.6M37.7M-189.0M—————
Fin CF—2.5M1.5M12.3M33.0M—————
Loading 1Y...
PRICE (1Y) · USD+0.2%
74.676.878.981.083.214 Sep5 Oct23 Oct
SMA 50SMA 200

Price checkIn an uptrendExperimental

Above its 200-day average and 9% below its 52-week high.

SwingsBumpy

Swung more than 63% of stocks we rank over the past year (50% a year).

How this is worked out

StockRank judges the business. The price check reads only the chart: it is the price side of the Momentum score, in words.

The rules: Still falling is a new 52-week low in the last two weeks, at least 25% below the high. Finding a floor is no new low since. Turning up is 20 or more trading days without a new low, at least 10% off it, and back above a rising 50-day average. In an uptrend is above the 200-day average and within 15% of the high.

In 2,112 US drawdowns since 2001, buying while the price was still falling was followed by a further 20% drop 42% of the time. Waiting for a turn like this one cut that to 33%, at about 7% higher prices and with no better returns. Part of that cut is simply not buying: 13% of falls never turned, and waiting kept those out. Among turns that were bought, 38% still fell another 20%, and 33% of turns were followed by a new low within six months. The benefit was largest in crashes such as 2008 and 2020.

What it measures: day-to-day price moves over the past year, as a yearly figure, ranked against every stock we cover. Very calm under 20% a year, Calm 20 to 30%, Average 30 to 40%, Bumpy 40 to 55%, Very bumpy above that.

What we found: across about 13,500 stocks in 34 markets (2002 to 2025), past swings were a good guide to the next year's, and bumpier stocks fell further. How much further changed too much between eras to put a number on it.

Calm is not safe: a calm stock can still slide steadily.

Rules fixed before any data was fetched. Describes the chart, not a recommendation.

Close
$76.73
RSI (14)
51.0
52-Week Range-8.7% from high
Low $35.20High $84.06

SCORE BREAKDOWN

Quality
83
ROIC
12.4%75.7
ROE
14.0%79.3
GP/Assets
60.0%92.0
Op. Margin
11.2%65.6
FCF/Assets
15.4%93.6
Piotroski
783.5
Int. Cover
50.0x89.5
D/E Ratio
0.01x83.3
Current Ratio
3.90x65.4
Value
17
P/E (TTM)
77.5x11.9
EV/EBITDA
53.6x9.8
P/FCF
50.9x24.6
P/B
9.1x11.6
P/S
7.1x30.7
Div Yield
—N/A
Momentum
75
52W High %
91%87.6
RS 6M
72%95.3
SMA 50/200
1.32x94.5
EPS Rev 4W
0.0%51.5
EPS Rev 12W
-5.0%18.0
EPS Improve
+65%62.5
Q Growth
43%71.5

FUNDAMENTALS

Market Cap
$6.0B
P/E (Forward)
47.1x
Gross Margin
54.5%

SECTOR PEERS

Closest peers in Healthcare, ranked by industry match, size, and score similarity. Cross-listings of KNSA are excluded.

TickerCompanyMkt CapStockRankSignal
KNSAKiniksa Pharmaceuticals International, plc(you)$6.0B79Buy
HIK.LHikma Pharmaceuticals PLC$4.6B93Strong Buy
HLNHaleon plc$45.2B80Strong Buy
EAH.LECO Animal Health Group plc$85M89Strong Buy
CTEC.LConvatec Group PLC$6.3B78Buy
LIVNLivaNova PLC$4.4B85Strong Buy
SN.LSmith & Nephew plc$12.9B87Strong Buy
GNS.LGenus plc$2.0B86Strong Buy
AGY.LAllergy Therapeutics plc$381M4Strong Sell
STX.LShield Therapeutics plc$79M29Sell

Peer medians: ROE -5.5% · P/E 23.9x · Gross margin 56.0%

Company Deep Dive

Business segments breakdown, earnings transcript analysis, management credibility scoring, competitive landscape, and scenario modelling.

Request Deep Dive(50 Feathers)

Kiniksa Pharmaceuticals International, plc (KNSA): Stock Score Summary

Kiniksa Pharmaceuticals International, plc (KNSA) has a MoatMap StockRank of 79/100 based on Quality (83/100), Value (17/100), and Momentum (75/100) factor scores. The current signal is BUY. Kiniksa sells ARCALYST for recurrent pericarditis and raised its 2026 sales guidance after a strong second quarter, showing real demand and a profitable commercial franchise. The business depends almost entirely on one product, and the valuation already reflects that growth.

Kiniksa Pharmaceuticals International, plc is a biopharmaceutical company dedicated to discovering, developing, and commercializing innovative therapeutics for patients with debilitating rare diseases. The company's strategic focus on underserved inflammatory and autoimmune conditions provides potential for orphan drug exclusivity, offering a strong competitive moat. Kiniksa aims to become a leader in developing targeted treatments for these specific, high-unmet-need patient populations.

Key Financial Metrics

Price$76.73
Market Cap$6.0B
P/E (TTM)77.51
P/E (Forward)47.07
Price/Book9.15
Return on Equity14.0%
Return on Invested Capital12.4%
Debt/Equity0.01x
Gross Margin54.5%
Operating Margin11.2%
Revenue Growth55.4%
Free Cash Flow$118M

Kiniksa Pharmaceuticals International, plc operates in the Drug Manufacturers - Specialty & Generic industry, part of the Healthcare sector (United Kingdom).

Frequently Asked Questions

What is Kiniksa Pharmaceuticals International, plc’s (KNSA) StockRank?
MoatMap’s StockRank for Kiniksa Pharmaceuticals International, plc (KNSA) is 79/100, with a Buy signal. It is a composite of Quality (83), Value (17), and Momentum (75), each scored against its sector. The composite is then ranked across MoatMap’s universe of 24,000+ stocks.
Does Kiniksa Pharmaceuticals International, plc have an economic moat?
Kiniksa Pharmaceuticals International, plc (KNSA) has a Quality factor score of 83/100. The Quality factor combines ROIC, Piotroski F-Score, and leverage: the financial fingerprints of a durable competitive advantage. A Quality score above 70 typically indicates a company with the characteristics of a moated business.
Is Kiniksa Pharmaceuticals International, plc a buy, hold, or sell?
MoatMap’s current signal for Kiniksa Pharmaceuticals International, plc (KNSA) is Buy, based on a StockRank of 79/100. Signals are derived mechanically from the StockRank composite and should be one input among many; combine with your own thesis on management, competitive position, and valuation.
What sector is Kiniksa Pharmaceuticals International, plc in?
Kiniksa Pharmaceuticals International, plc (KNSA) operates in the Healthcare sector, specifically the Drug Manufacturers - Specialty & Generic industry (United Kingdom).