LONA

Strong SellSinker

LeonaBio, Inc. · Healthcare · United States · $55M cap · $1.7M/day traded

$4.76 -1.7% · close 26 Oct · scored 27 Oct

Sinker: Weak, expensive and falling. Nothing here to keep it afloat.

7
StockRank
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Quality
30
Value
32
Momentum
15

As of 27 Oct 2026, MoatMap's StockRank for LeonaBio, Inc. (LONA) is 7/100, ranked against 24,000+ stocks in 35 markets (Quality 30, Value 32, Momentum 15, each scored against its sector).

Does StockRank work? Each month we publish how every decile did, whichever way it went. See the record →

P/E (TTM)
—
peers 27.2x
ROE
-431.4%
peers -30.1%
D/E
0.0x
peers 0.2x
Dividend %
—
trailing yield

ABOUT LEONABIO, INC.

Read

LeonaBio, Inc. is a clinical-stage biotechnology company focused on developing novel gene therapies for rare genetic diseases, leveraging cutting-edge advancements in gene editing and delivery platforms. The company aims to provide potentially curative treatments by directly addressing the root causes of genetic disorders. Its specialized focus on developing transformative therapies for underserved patient populations provides a competitive niche in the burgeoning gene therapy market.

FINANCIAL SUMMARY (USD)

Year2022202320242025CAGRTTM
Revenue0000——
EPS-10.20-12.56-10.47-24.70—-23.01
Shares9.4M9.4M9.4M9.3M-0.6%9.4M
Debt1.9M1.6M1.2M0.8M-25.1%0.6M
Equity235.1M130.2M44.8M27.8M-50.9%—
Op CF-72.5M-100.8M-97.2M-45.7M—-61.9M
Inv CF57.7M95.1M54.8M-15.9M——
Fin CF0.7M0.5M0.2M82.5M——
Loading 1Y...
PRICE (1Y) · USD-34.3%
2.94.05.16.17.215 Sep6 Oct26 Oct
SMA 50SMA 200

Price checkFinding a floorExperimental

No new 52-week low for 4 weeks, 115% above that low, but not back above a rising 50-day average.

SwingsVery bumpy

Swung more than 98% of stocks we rank over the past year (120% a year).

How this is worked out

StockRank judges the business. The price check reads only the chart: it is the price side of the Momentum score, in words.

The rules: Still falling is a new 52-week low in the last two weeks, at least 25% below the high. Finding a floor is no new low since. Turning up is 20 or more trading days without a new low, at least 10% off it, and back above a rising 50-day average. In an uptrend is above the 200-day average and within 15% of the high.

In 2,112 US drawdowns since 2001, buying while the price was still falling was followed by a further 20% drop 42% of the time. Waiting for a turn like this one cut that to 33%, at about 7% higher prices and with no better returns. Part of that cut is simply not buying: 13% of falls never turned, and waiting kept those out. Among turns that were bought, 38% still fell another 20%, and 33% of turns were followed by a new low within six months. The benefit was largest in crashes such as 2008 and 2020.

What it measures: day-to-day price moves over the past year, as a yearly figure, ranked against every stock we cover. Very calm under 20% a year, Calm 20 to 30%, Average 30 to 40%, Bumpy 40 to 55%, Very bumpy above that.

What we found: across about 13,500 stocks in 34 markets (2002 to 2025), past swings were a good guide to the next year's, and bumpier stocks fell further. How much further changed too much between eras to put a number on it.

Calm is not safe: a calm stock can still slide steadily.

Rules fixed before any data was fetched. Describes the chart, not a recommendation.

Close
$4.76
RSI (14)
36.8
52-Week Range-66.5% from high
Low $2.21High $14.21

SCORE BREAKDOWN

Quality
30
ROIC
-122.7%5.1
ROE
-431.4%1.9
GP/Assets
—N/A
Op. Margin
0.0%38.6
FCF/Assets
-25.1%18.1
Piotroski
438.6
Int. Cover
—N/A
D/E Ratio
0.02x81.1
Current Ratio
7.01x81.1
Value
32
P/E (TTM)
—N/A
EV/EBITDA
0.1x25.0
P/FCF
—N/A
P/B
1.4x74.0
P/S
—N/A
Div Yield
—N/A
Momentum
15
52W High %
33%11.9
RS 6M
-50%11.0
SMA 50/200
0.83x19.4
EPS Rev 4W
—N/A
EPS Rev 12W
—N/A
EPS Improve
—N/A
Q Growth
—N/A

FUNDAMENTALS

Market Cap
$55M
P/E (Forward)
—
Gross Margin
—

SECTOR PEERS

Closest peers in Healthcare, ranked by industry match, size, and score similarity. Cross-listings of LONA are excluded.

TickerCompanyMkt CapStockRankSignal
LONALeonaBio, Inc.(you)$55M7Strong Sell
CNTXContext Therapeutics Inc.$56M8Strong Sell
IBOImpact BioMedical Inc.$57M8Strong Sell
ATYRaTyr Pharma, Inc.$53M6Strong Sell
OSTXOS Therapies Incorporated$59M8Strong Sell
HRTXHeron Therapeutics, Inc.$57M9Strong Sell
GOSSGossamer Bio, Inc.$59M5Strong Sell
ANVSAnnovis Bio, Inc.$54M10Strong Sell
TCRXTScan Therapeutics, Inc.$51M9Strong Sell
SERSerina Therapeutics, Inc.$56M11Strong Sell

Peer medians: ROE -30.1% · P/E 27.2x · Gross margin 63.3%

Company Deep Dive

Business segments breakdown, earnings transcript analysis, management credibility scoring, competitive landscape, and scenario modelling.

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LeonaBio, Inc. (LONA): Stock Score Summary

LeonaBio, Inc. (LONA) has a MoatMap StockRank of 7/100 based on Quality (30/100), Value (32/100), and Momentum (15/100) factor scores. The current signal is STRONG SELL.

LeonaBio, Inc. is a clinical-stage biotechnology company focused on developing novel gene therapies for rare genetic diseases, leveraging cutting-edge advancements in gene editing and delivery platforms. The company aims to provide potentially curative treatments by directly addressing the root causes of genetic disorders. Its specialized focus on developing transformative therapies for underserved patient populations provides a competitive niche in the burgeoning gene therapy market.

Key Financial Metrics

Price$4.76
Market Cap$55M
Price/Book1.36
Return on Equity-431.4%
Return on Invested Capital-122.7%
Debt/Equity0.02x
Operating Margin0.0%
Free Cash Flow$-23M

LeonaBio, Inc. operates in the Biotechnology industry, part of the Healthcare sector (United States).

Frequently Asked Questions

What is LeonaBio, Inc.’s (LONA) StockRank?
MoatMap’s StockRank for LeonaBio, Inc. (LONA) is 7/100, with a Strong Sell signal. It is a composite of Quality (30), Value (32), and Momentum (15), each scored against its sector. The composite is then ranked across MoatMap’s universe of 24,000+ stocks.
Does LeonaBio, Inc. have an economic moat?
LeonaBio, Inc. (LONA) has a Quality factor score of 30/100. The Quality factor combines ROIC, Piotroski F-Score, and leverage: the financial fingerprints of a durable competitive advantage. A Quality score above 70 typically indicates a company with the characteristics of a moated business.
Is LeonaBio, Inc. a buy, hold, or sell?
MoatMap’s current signal for LeonaBio, Inc. (LONA) is Strong Sell, based on a StockRank of 7/100. Signals are derived mechanically from the StockRank composite and should be one input among many; combine with your own thesis on management, competitive position, and valuation.
What sector is LeonaBio, Inc. in?
LeonaBio, Inc. (LONA) operates in the Healthcare sector, specifically the Biotechnology industry (United States).