NAUT

Strong SellSinker

Nautilus Biotechnology, Inc. · Healthcare · United States · $412M cap · $21.4M/day traded

$2.44 -24.7% · close 26 Oct · scored 27 Oct

StockRank down 7.9 since 24 Oct: Momentum down 13 after a 25% price fall, Value down 3.

Sinker: Weak, expensive and falling. Nothing here to keep it afloat.

9
StockRank
Get score and insider alerts
Quality
24
Value
25
Momentum
33

As of 27 Oct 2026, MoatMap's StockRank for Nautilus Biotechnology, Inc. (NAUT) is 9/100, ranked against 24,000+ stocks in 35 markets (Quality 24, Value 25, Momentum 33, each scored against its sector).

Does StockRank work? Each month we publish how every decile did, whichever way it went. See the record →

P/E (TTM)
—
peers 27.2x
ROE
-36.2%
peers -30.1%
D/E
0.2x
peers 0.2x
Dividend %
—
trailing yield

ABOUT NAUTILUS BIOTECHNOLOGY, INC.

Read

Nautilus Biotechnology, Inc. is a biotechnology company developing a transformative single-molecule protein analysis platform designed to revolutionize proteomics through ultra-sensitive, high-throughput, and quantitative protein detection. The company's competitive moat is based on its proprietary protein sequencing technology, which holds the potential to provide unprecedented insights into the proteome, thereby significantly advancing biological research and drug discovery. Nautilus is an innovative, early-stage player with the ambition to disrupt the proteomics market.

FINANCIAL SUMMARY (USD)

Year20212022202320242025CAGRTTM2026E2027EFwd CAGR
Revenue—0000——0.5M5.2M—
EPS-0.60-0.46-0.51-0.56-0.47—-0.45-0.51-0.52—
Shares—124.9M125.1M126.1M126.5M+1.3%127.3M———
Debt—30.3M34.6M30.5M30.0M-0.3%27.8M———
Equity—314.9M265.4M208.7M157.0M-20.7%————
Op CF—-45.8M-51.7M-59.1M-50.7M—-50.2M———
Inv CF—-25.7M-43.7M66.3M35.2M—————
Fin CF—0.6M0.4M1.1M0.2M—————
Loading 1Y...
PRICE (1Y) · USD+173.8%
0.91.52.12.73.215 Sep6 Oct26 Oct
SMA 50SMA 200

Price checkTurning upExperimental

190% above its 52-week low and back above a rising 50-day average since 19 Oct 2026.

The Momentum score still reads 33: it weighs six months of price and earnings revisions, so it trails a turn like this.

SwingsVery bumpy

Swung more than 98% of stocks we rank over the past year (123% a year).

How this is worked out

StockRank judges the business. The price check reads only the chart: it is the price side of the Momentum score, in words.

The rules: Still falling is a new 52-week low in the last two weeks, at least 25% below the high. Finding a floor is no new low since. Turning up is 20 or more trading days without a new low, at least 10% off it, and back above a rising 50-day average. In an uptrend is above the 200-day average and within 15% of the high.

In 2,112 US drawdowns since 2001, buying while the price was still falling was followed by a further 20% drop 42% of the time. Waiting for a turn like this one cut that to 33%, at about 7% higher prices and with no better returns. Part of that cut is simply not buying: 13% of falls never turned, and waiting kept those out. Among turns that were bought, 38% still fell another 20%, and 33% of turns were followed by a new low within six months. The benefit was largest in crashes such as 2008 and 2020.

What it measures: day-to-day price moves over the past year, as a yearly figure, ranked against every stock we cover. Very calm under 20% a year, Calm 20 to 30%, Average 30 to 40%, Bumpy 40 to 55%, Very bumpy above that.

What we found: across about 13,500 stocks in 34 markets (2002 to 2025), past swings were a good guide to the next year's, and bumpier stocks fell further. How much further changed too much between eras to put a number on it.

Calm is not safe: a calm stock can still slide steadily.

Rules fixed before any data was fetched. Describes the chart, not a recommendation.

Close
$2.44
RSI (14)
59.5
52-Week Range-43.4% from high
Low $0.841High $4.31

SCORE BREAKDOWN

Quality
24
ROIC
-36.5%20.7
ROE
-36.2%22.9
GP/Assets
0.1%10.6
Op. Margin
-8296.3%2.4
FCF/Assets
-15.1%25.9
Piotroski
12.3
Int. Cover
—N/A
D/E Ratio
0.21x49.2
Current Ratio
10.14x87.4
Value
25
P/E (TTM)
—N/A
EV/EBITDA
-5.8x25.0
P/FCF
—N/A
P/B
3.1x40.0
P/S
2170.0x1.4
Div Yield
—N/A
Momentum
33
52W High %
57%35.5
RS 6M
-12%48.2
SMA 50/200
0.68x7.0
EPS Rev 4W
0.0%51.1
EPS Rev 12W
0.0%43.8
EPS Improve
-64%8.3
Q Growth
—N/A

FUNDAMENTALS

Market Cap
$412M
P/E (Forward)
-4.4x
Gross Margin
92.1%

SECTOR PEERS

Closest peers in Healthcare, ranked by industry match, size, and score similarity. Cross-listings of NAUT are excluded.

TickerCompanyMkt CapStockRankSignal
NAUTNautilus Biotechnology, Inc.(you)$412M9Strong Sell
ALLOAllogene Therapeutics, Inc.$432M10Strong Sell
RGNXREGENXBIO Inc.$441M10Strong Sell
EIKNEikon Therapeutics, Inc.$393M8Strong Sell
TRXBTRex Bio, Inc.$379M10Strong Sell
MPLTMapLight Therapeutics, Inc.$443M12Strong Sell
EDITEditas Medicine, Inc.$369M12Strong Sell
ALTAltimmune, Inc.$412M14Strong Sell
BLSMBlossomHill Therapeutics, Inc.$465M6Strong Sell
CTMXCytomX Therapeutics, Inc.$506M11Strong Sell

Peer medians: ROE -30.1% · P/E 27.2x · Gross margin 63.3%

Company Deep Dive

Business segments breakdown, earnings transcript analysis, management credibility scoring, competitive landscape, and scenario modelling.

Request Deep Dive(50 Feathers)

Nautilus Biotechnology, Inc. (NAUT): Stock Score Summary

Nautilus Biotechnology, Inc. (NAUT) has a MoatMap StockRank of 9/100 based on Quality (24/100), Value (25/100), and Momentum (33/100) factor scores. The current signal is STRONG SELL.

Nautilus Biotechnology, Inc. is a biotechnology company developing a transformative single-molecule protein analysis platform designed to revolutionize proteomics through ultra-sensitive, high-throughput, and quantitative protein detection. The company's competitive moat is based on its proprietary protein sequencing technology, which holds the potential to provide unprecedented insights into the proteome, thereby significantly advancing biological research and drug discovery. Nautilus is an innovative, early-stage player with the ambition to disrupt the proteomics market.

Key Financial Metrics

Price$2.44
Market Cap$412M
P/E (Forward)-4.38
Price/Book3.14
Return on Equity-36.2%
Return on Invested Capital-36.5%
Debt/Equity0.21x
Gross Margin92.1%
Operating Margin-8296.3%
Free Cash Flow$-29M

Nautilus Biotechnology, Inc. operates in the Biotechnology industry, part of the Healthcare sector (United States).

Frequently Asked Questions

What is Nautilus Biotechnology, Inc.’s (NAUT) StockRank?
MoatMap’s StockRank for Nautilus Biotechnology, Inc. (NAUT) is 9/100, with a Strong Sell signal. It is a composite of Quality (24), Value (25), and Momentum (33), each scored against its sector. The composite is then ranked across MoatMap’s universe of 24,000+ stocks.
Does Nautilus Biotechnology, Inc. have an economic moat?
Nautilus Biotechnology, Inc. (NAUT) has a Quality factor score of 24/100. The Quality factor combines ROIC, Piotroski F-Score, and leverage: the financial fingerprints of a durable competitive advantage. A Quality score above 70 typically indicates a company with the characteristics of a moated business.
Is Nautilus Biotechnology, Inc. a buy, hold, or sell?
MoatMap’s current signal for Nautilus Biotechnology, Inc. (NAUT) is Strong Sell, based on a StockRank of 9/100. Signals are derived mechanically from the StockRank composite and should be one input among many; combine with your own thesis on management, competitive position, and valuation.
What sector is Nautilus Biotechnology, Inc. in?
Nautilus Biotechnology, Inc. (NAUT) operates in the Healthcare sector, specifically the Biotechnology industry (United States).