PRTA

Strong SellSinker

Prothena Corporation plc · Healthcare · Ireland · $446M cap · $4.3M/day traded

$8.43 -4.6% · close 12 Oct · scored 14 Oct

Sinker: Weak, expensive and falling. Nothing here to keep it afloat.

15
StockRank
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Quality
27
Value
32
Momentum
34

As of 14 Oct 2026, MoatMap's StockRank for Prothena Corporation plc (PRTA) is 15/100, ranked against 24,000+ stocks in 35 markets (Quality 27, Value 32, Momentum 34, each scored against its sector).

Does StockRank work? Each month we publish how every decile did, whichever way it went. See the record →

P/E (TTM)
—
peers 21.5x
ROE
-14.4%
peers 2.1%
D/E
0.0x
peers 0.6x
Dividend %
—
trailing yield

ABOUT PROTHENA CORPORATION PLC

Read

Prothena Corporation plc is a clinical-stage neuroscience company specializing in the discovery and development of novel antibodies and immunotherapies for neurodegenerative diseases. Its robust pipeline targets critical protein misfolding conditions such as amyloidosis, Parkinson's, and Alzheimer's disease. The company leverages deep scientific expertise in protein dysregulation to create targeted treatments addressing significant unmet medical needs.

FINANCIAL SUMMARY (USD)

Year2022202320242025CAGRTTM2026E2027EFwd CAGR
Revenue53.9M91.4M135.2M9.7M-43.6%54.5M83.2M24.4M58.7%
EPS-2.47-2.76-2.27-4.53—-0.82-0.55-1.52—
Shares52.1M53.7M53.8M53.8M+3.3%51.3M———
Debt6.5M11.8M10.8M8.4M9.0%7.0M———
Equity622.0M561.4M486.9M280.5M-23.3%————
Op CF-108.8M-133.9M-150.1M-163.6M—-60.0M———
Inv CF-0.5M-2.8M-0.3M-0.1M—————
Fin CF241.5M45.1M1.6M-0.1M—————
Loading 1Y...
PRICE (1Y) · USD-9.8%
8.08.58.99.49.831 Aug22 Sep12 Oct
SMA 50SMA 200

Price checkFinding a floorExperimental

No new 52-week low for 16 weeks, 9% above that low, but not back above a rising 50-day average.

SwingsBumpy

Swung more than 61% of stocks we rank over the past year (48% a year).

How this is worked out

StockRank judges the business. The price check reads only the chart: it is the price side of the Momentum score, in words.

The rules: Still falling is a new 52-week low in the last two weeks, at least 25% below the high. Finding a floor is no new low since. Turning up is 20 or more trading days without a new low, at least 10% off it, and back above a rising 50-day average. In an uptrend is above the 200-day average and within 15% of the high.

In 2,112 US drawdowns since 2001, buying while the price was still falling was followed by a further 20% drop 42% of the time. Waiting for a turn like this one cut that to 33%, at about 7% higher prices and with no better returns. Part of that cut is simply not buying: 13% of falls never turned, and waiting kept those out. Among turns that were bought, 38% still fell another 20%, and 33% of turns were followed by a new low within six months. The benefit was largest in crashes such as 2008 and 2020.

What it measures: day-to-day price moves over the past year, as a yearly figure, ranked against every stock we cover. Very calm under 20% a year, Calm 20 to 30%, Average 30 to 40%, Bumpy 40 to 55%, Very bumpy above that.

What we found: across about 13,500 stocks in 34 markets (2002 to 2025), past swings were a good guide to the next year's, and bumpier stocks fell further. How much further changed too much between eras to put a number on it.

Calm is not safe: a calm stock can still slide steadily.

Rules fixed before any data was fetched. Describes the chart, not a recommendation.

Close
$8.43
RSI (14)
42.0
52-Week Range-28.6% from high
Low $7.73High $11.80

SCORE BREAKDOWN

Quality
27
ROIC
-20.9%27.7
ROE
-14.4%32.0
GP/Assets
-3.2%7.2
Op. Margin
-1850.2%5.4
FCF/Assets
-50.1%7.3
Piotroski
29.2
Int. Cover
—N/A
D/E Ratio
0.02x78.5
Current Ratio
25.05x97.1
Value
32
P/E (TTM)
—N/A
EV/EBITDA
-2.9x25.0
P/FCF
—N/A
P/B
1.6x69.7
P/S
8.3x28.4
Div Yield
—N/A
Momentum
34
52W High %
71%55.0
RS 6M
-32%31.8
SMA 50/200
0.95x44.8
EPS Rev 4W
0.0%48.7
EPS Rev 12W
-16.0%9.0
EPS Improve
-85%6.2
Q Growth
—N/A

FUNDAMENTALS

Market Cap
$446M
P/E (Forward)
-5.8x
Gross Margin
—

SECTOR PEERS

Closest peers in Healthcare, ranked by industry match, size, and score similarity. Cross-listings of PRTA are excluded.

TickerCompanyMkt CapStockRankSignal
PRTAProthena Corporation plc(you)$446M15Strong Sell
GHRSGH Research PLC$1.8B29Sell
CMHC.SWCosmo N.V.$1.1B19Strong Sell
AMRNAmarin Corporation plc$290M34Sell
COPN.SWCosmo NV$1.2B25Sell
ONE.AXOneview Healthcare PLC$93M15Strong Sell
JAZZJazz Pharmaceuticals plc$15.2B91Strong Buy
UPR.LUniphar plc$1.2B67Buy
PRGOPerrigo Company plc$1.9B73Buy
ALKSAlkermes plc$7.1B58Hold

Peer medians: ROE 2.1% · P/E 21.5x · Gross margin 45.5%

Company Deep Dive

Business segments breakdown, earnings transcript analysis, management credibility scoring, competitive landscape, and scenario modelling.

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Prothena Corporation plc (PRTA): Stock Score Summary

Prothena Corporation plc (PRTA) has a MoatMap StockRank of 15/100 based on Quality (27/100), Value (32/100), and Momentum (34/100) factor scores. The current signal is STRONG SELL.

Prothena Corporation plc is a clinical-stage neuroscience company specializing in the discovery and development of novel antibodies and immunotherapies for neurodegenerative diseases. Its robust pipeline targets critical protein misfolding conditions such as amyloidosis, Parkinson's, and Alzheimer's disease. The company leverages deep scientific expertise in protein dysregulation to create targeted treatments addressing significant unmet medical needs.

Key Financial Metrics

Price$8.43
Market Cap$446M
P/E (Forward)-5.82
Price/Book1.59
Return on Equity-14.4%
Return on Invested Capital-20.9%
Debt/Equity0.02x
Operating Margin-1850.2%
Revenue Growth-77.1%
Free Cash Flow$-164M

Prothena Corporation plc operates in the Biotechnology industry, part of the Healthcare sector (Ireland).

Frequently Asked Questions

What is Prothena Corporation plc’s (PRTA) StockRank?
MoatMap’s StockRank for Prothena Corporation plc (PRTA) is 15/100, with a Strong Sell signal. It is a composite of Quality (27), Value (32), and Momentum (34), each scored against its sector. The composite is then ranked across MoatMap’s universe of 24,000+ stocks.
Does Prothena Corporation plc have an economic moat?
Prothena Corporation plc (PRTA) has a Quality factor score of 27/100. The Quality factor combines ROIC, Piotroski F-Score, and leverage: the financial fingerprints of a durable competitive advantage. A Quality score above 70 typically indicates a company with the characteristics of a moated business.
Is Prothena Corporation plc a buy, hold, or sell?
MoatMap’s current signal for Prothena Corporation plc (PRTA) is Strong Sell, based on a StockRank of 15/100. Signals are derived mechanically from the StockRank composite and should be one input among many; combine with your own thesis on management, competitive position, and valuation.
What sector is Prothena Corporation plc in?
Prothena Corporation plc (PRTA) operates in the Healthcare sector, specifically the Biotechnology industry (Ireland).