QURE

Strong SellHot Air

uniQure N.V. · Healthcare · Netherlands · $1.6B cap · $65.1M/day traded

$22.43 -2.9% · close 23 Oct · scored 24 Oct

Hot Air: Rising on momentum alone: weak business, rich price.

16
StockRank
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Quality
22
Value
24
Momentum
50

As of 24 Oct 2026, MoatMap's StockRank for uniQure N.V. (QURE) is 16/100, ranked against 24,000+ stocks in 35 markets (Quality 22, Value 24, Momentum 50, each scored against its sector).

Does StockRank work? Each month we publish how every decile did, whichever way it went. See the record →

P/E (TTM)
—
peers 28.5x
ROE
-157.6%
peers 6.9%
D/E
1.7x
peers 0.4x
Dividend %
—
trailing yield

ABOUT UNIQURE N.V.

Read

uniQure N.V. is a pioneering gene therapy company dedicated to developing and commercializing transformative one-time treatments for severe genetic diseases. Leveraging its proprietary AAV gene therapy platform, the company has an approved product for hemophilia B in Europe and a robust pipeline targeting neurological and liver diseases. uniQure maintains a competitive edge through its advanced technology and integrated manufacturing capabilities.

FINANCIAL SUMMARY (USD)

Year2022202320242025CAGRTTM2026E2027EFwd CAGR
Revenue106.5M15.8M27.1M16.1M-46.7%18.7M24.9M—54.8%
EPS-2.71-6.47-4.92-3.46—-4.03-3.44-2.64—
Shares47.0M47.8M49.0M62.5M+33.1%69.4M———
Debt142.9M138.4M66.1M63.4M-23.7%552.2M———
Equity476.0M207.7M-6.8M198.9M-25.2%————
Op CF-145.1M-145.9M-182.7M-178.0M—-160.8M———
Inv CF-182.7M-205.7M163.0M-321.6M—————
Fin CF1.4M362.7M-59.5M415.4M—————
Loading 1Y...
PRICE (1Y) · USD-50.1%
21.027.033.139.245.314 Sep5 Oct23 Oct
SMA 50SMA 200

Price checkFinding a floorExperimental

No new 52-week low for 32 weeks, 157% above that low, but not back above a rising 50-day average.

The Momentum score still reads 50: it looks back six months, so it has not caught up with this fall.

SwingsVery bumpy

Swung more than 99% of stocks we rank over the past year (143% a year).

How this is worked out

StockRank judges the business. The price check reads only the chart: it is the price side of the Momentum score, in words.

The rules: Still falling is a new 52-week low in the last two weeks, at least 25% below the high. Finding a floor is no new low since. Turning up is 20 or more trading days without a new low, at least 10% off it, and back above a rising 50-day average. In an uptrend is above the 200-day average and within 15% of the high.

In 2,112 US drawdowns since 2001, buying while the price was still falling was followed by a further 20% drop 42% of the time. Waiting for a turn like this one cut that to 33%, at about 7% higher prices and with no better returns. Part of that cut is simply not buying: 13% of falls never turned, and waiting kept those out. Among turns that were bought, 38% still fell another 20%, and 33% of turns were followed by a new low within six months. The benefit was largest in crashes such as 2008 and 2020.

What it measures: day-to-day price moves over the past year, as a yearly figure, ranked against every stock we cover. Very calm under 20% a year, Calm 20 to 30%, Average 30 to 40%, Bumpy 40 to 55%, Very bumpy above that.

What we found: across about 13,500 stocks in 34 markets (2002 to 2025), past swings were a good guide to the next year's, and bumpier stocks fell further. How much further changed too much between eras to put a number on it.

Calm is not safe: a calm stock can still slide steadily.

Rules fixed before any data was fetched. Describes the chart, not a recommendation.

Close
$22.43
RSI (14)
47.3
52-Week Range-68.6% from high
Low $8.73High $71.50

SCORE BREAKDOWN

Quality
22
ROIC
-24.3%26.4
ROE
-157.6%5.6
GP/Assets
-13.9%5.4
Op. Margin
-872.2%7.2
FCF/Assets
-21.6%20.6
Piotroski
549.0
Int. Cover
-3.1x29.4
D/E Ratio
1.70x7.2
Current Ratio
10.01x87.4
Value
24
P/E (TTM)
—N/A
EV/EBITDA
-7.1x25.0
P/FCF
—N/A
P/B
4.8x28.0
P/S
83.3x7.0
Div Yield
—N/A
Momentum
50
52W High %
31%10.9
RS 6M
17%78.5
SMA 50/200
1.25x91.4
EPS Rev 4W
+1.4%89.8
EPS Rev 12W
-4.3%19.4
EPS Improve
+26%37.8
Q Growth
—N/A

FUNDAMENTALS

Market Cap
$1.6B
P/E (Forward)
-7.6x
Gross Margin
89.5%

SECTOR PEERS

Closest peers in Healthcare, ranked by industry match, size, and score similarity. Cross-listings of QURE are excluded.

TickerCompanyMkt CapStockRankSignal
QUREuniQure N.V.(you)$1.6B16Strong Sell
NAMSNewAmsterdam Pharma Company N.V.$2.3B10Strong Sell
PHARPharming Group N.V.$793M34Sell
PRQRProQR Therapeutics N.V.$182M17Strong Sell
ONWD.BROnward Medical N.V.$161M11Strong Sell
ARGXargenx SE$54.9B64Hold
RDC.DERedcare Pharmacy NV$1.8B62Hold
QGENQiagen N.V.$10.4B79Buy
PHGKoninklijke Philips N.V.$26.3B85Strong Buy

Peer medians: ROE 6.9% · P/E 28.5x · Gross margin 66.4%

Company Deep Dive

Business segments breakdown, earnings transcript analysis, management credibility scoring, competitive landscape, and scenario modelling.

Request Deep Dive(50 Feathers)

uniQure N.V. (QURE): Stock Score Summary

uniQure N.V. (QURE) has a MoatMap StockRank of 16/100 based on Quality (22/100), Value (24/100), and Momentum (50/100) factor scores. The current signal is STRONG SELL.

uniQure N.V. is a pioneering gene therapy company dedicated to developing and commercializing transformative one-time treatments for severe genetic diseases. Leveraging its proprietary AAV gene therapy platform, the company has an approved product for hemophilia B in Europe and a robust pipeline targeting neurological and liver diseases. uniQure maintains a competitive edge through its advanced technology and integrated manufacturing capabilities.

Key Financial Metrics

Price$22.43
Market Cap$1.6B
P/E (Forward)-7.56
Price/Book4.80
Return on Equity-157.6%
Return on Invested Capital-24.3%
Debt/Equity1.70x
Gross Margin89.5%
Operating Margin-872.2%
Revenue Growth11.0%
Free Cash Flow$-178M

uniQure N.V. operates in the Biotechnology industry, part of the Healthcare sector (Netherlands).

Frequently Asked Questions

What is uniQure N.V.’s (QURE) StockRank?
MoatMap’s StockRank for uniQure N.V. (QURE) is 16/100, with a Strong Sell signal. It is a composite of Quality (22), Value (24), and Momentum (50), each scored against its sector. The composite is then ranked across MoatMap’s universe of 24,000+ stocks.
Does uniQure N.V. have an economic moat?
uniQure N.V. (QURE) has a Quality factor score of 22/100. The Quality factor combines ROIC, Piotroski F-Score, and leverage: the financial fingerprints of a durable competitive advantage. A Quality score above 70 typically indicates a company with the characteristics of a moated business.
Is uniQure N.V. a buy, hold, or sell?
MoatMap’s current signal for uniQure N.V. (QURE) is Strong Sell, based on a StockRank of 16/100. Signals are derived mechanically from the StockRank composite and should be one input among many; combine with your own thesis on management, competitive position, and valuation.
What sector is uniQure N.V. in?
uniQure N.V. (QURE) operates in the Healthcare sector, specifically the Biotechnology industry (Netherlands).