SPTX

Strong SellSinker

Seaport Therapeutics, Inc. · Healthcare · United States · $1.1B cap · $5.6M/day traded

$20.83 +1.1% · close 26 Oct · scored 27 Oct

StockRank down 1.0 since 24 Oct.

Sinker: Weak, expensive and falling. Nothing here to keep it afloat.

17
StockRank
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Quality
32
Value
28
Momentum
37

As of 27 Oct 2026, MoatMap's StockRank for Seaport Therapeutics, Inc. (SPTX) is 17/100, ranked against 24,000+ stocks in 35 markets (Quality 32, Value 28, Momentum 37, each scored against its sector).

Does StockRank work? Each month we publish how every decile did, whichever way it went. See the record →

P/E (TTM)
—
peers 27.2x
ROE
—
peers -30.2%
D/E
0.0x
peers 0.2x
Dividend %
—
trailing yield

ABOUT SEAPORT THERAPEUTICS, INC.

Read

Seaport Therapeutics, Inc., a clinical-stage therapeutics company, focuses on inventing and developing new medicines for patients with depression, anxiety, and other debilitating neuropsychiatric disorders.

FINANCIAL SUMMARY (USD)

Year20242025TTM2026E2027EFwd CAGR
Revenue00————
EPS-1.21-1.94-5.81-5.59-2.52—
Shares53.0M53.0M53.5M———
Debt5.0M5.1M5.0M———
Equity-24.8M-92.5M————
Op CF-29.6M-77.9M-88.7M———
Inv CF-0.1M-184.2M————
Fin CF339.3M-0.9M————
Loading 1Y...
PRICE (1Y) · USD-9.3%
16.117.819.521.223.015 Sep6 Oct26 Oct
SMA 50SMA 200

Price checkNo read yetExperimental

Not enough steady price history for a read yet.

How this is worked out

StockRank judges the business. The price check reads only the chart: it is the price side of the Momentum score, in words.

The rules: Still falling is a new 52-week low in the last two weeks, at least 25% below the high. Finding a floor is no new low since. Turning up is 20 or more trading days without a new low, at least 10% off it, and back above a rising 50-day average. In an uptrend is above the 200-day average and within 15% of the high.

In 2,112 US drawdowns since 2001, buying while the price was still falling was followed by a further 20% drop 42% of the time. Waiting for a turn like this one cut that to 33%, at about 7% higher prices and with no better returns. Part of that cut is simply not buying: 13% of falls never turned, and waiting kept those out. Among turns that were bought, 38% still fell another 20%, and 33% of turns were followed by a new low within six months. The benefit was largest in crashes such as 2008 and 2020.

Rules fixed before any data was fetched. Describes the chart, not a recommendation.

Close
$20.83
RSI (14)
71.6

SCORE BREAKDOWN

Quality
32
ROIC
-37.0%20.6
ROE
—N/A
GP/Assets
—N/A
Op. Margin
0.0%38.6
FCF/Assets
-31.4%14.3
Piotroski
12.3
Int. Cover
—N/A
D/E Ratio
0.01x83.9
Current Ratio
18.00x94.8
Value
28
P/E (TTM)
—N/A
EV/EBITDA
-5.8x25.0
P/FCF
—N/A
P/B
2.6x48.0
P/S
—N/A
Div Yield
—N/A
Momentum
37
52W High %
—N/A
RS 6M
—N/A
SMA 50/200
—N/A
EPS Rev 4W
+2.0%89.4
EPS Rev 12W
-2.2%23.6
EPS Improve
+57%58.0
Q Growth
—N/A

FUNDAMENTALS

Market Cap
$1.1B
P/E (Forward)
-8.2x
Gross Margin
—

SECTOR PEERS

Closest peers in Healthcare, ranked by industry match, size, and score similarity. Cross-listings of SPTX are excluded.

TickerCompanyMkt CapStockRankSignal
SPTXSeaport Therapeutics, Inc.(you)$1.1B17Strong Sell
NKTRNektar Therapeutics$1.3B17Strong Sell
BCAXBicara Therapeutics Inc.$1.1B14Strong Sell
SGPSpyGlass Pharma, Inc.$953M17Strong Sell
KARDKardigan, Inc.$1.2B14Strong Sell
ORICORIC Pharmaceuticals, Inc.$1.4B16Strong Sell
AVBPArriVent BioPharma, Inc.$1.0B13Strong Sell
REPLReplimune Group, Inc.$1.1B24Sell
LBRXLB Pharmaceuticals Inc$1.2B22Sell
RAPPRapport Therapeutics, Inc.$1.2B12Strong Sell

Peer medians: ROE -30.2% · P/E 27.2x · Gross margin 63.3%

Company Deep Dive

Business segments breakdown, earnings transcript analysis, management credibility scoring, competitive landscape, and scenario modelling.

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Seaport Therapeutics, Inc. (SPTX): Stock Score Summary

Seaport Therapeutics, Inc. (SPTX) has a MoatMap StockRank of 17/100 based on Quality (32/100), Value (28/100), and Momentum (37/100) factor scores. The current signal is STRONG SELL.

Seaport Therapeutics, Inc., a clinical-stage therapeutics company, focuses on inventing and developing new medicines for patients with depression, anxiety, and other debilitating neuropsychiatric disorders.

Key Financial Metrics

Price$20.83
Market Cap$1.1B
P/E (Forward)-8.17
Price/Book2.61
Return on Invested Capital-37.0%
Debt/Equity0.01x
Operating Margin0.0%
Free Cash Flow$-78M

Seaport Therapeutics, Inc. operates in the Biotechnology industry, part of the Healthcare sector (United States).

Frequently Asked Questions

What is Seaport Therapeutics, Inc.’s (SPTX) StockRank?
MoatMap’s StockRank for Seaport Therapeutics, Inc. (SPTX) is 17/100, with a Strong Sell signal. It is a composite of Quality (32), Value (28), and Momentum (37), each scored against its sector. The composite is then ranked across MoatMap’s universe of 24,000+ stocks.
Does Seaport Therapeutics, Inc. have an economic moat?
Seaport Therapeutics, Inc. (SPTX) has a Quality factor score of 32/100. The Quality factor combines ROIC, Piotroski F-Score, and leverage: the financial fingerprints of a durable competitive advantage. A Quality score above 70 typically indicates a company with the characteristics of a moated business.
Is Seaport Therapeutics, Inc. a buy, hold, or sell?
MoatMap’s current signal for Seaport Therapeutics, Inc. (SPTX) is Strong Sell, based on a StockRank of 17/100. Signals are derived mechanically from the StockRank composite and should be one input among many; combine with your own thesis on management, competitive position, and valuation.
What sector is Seaport Therapeutics, Inc. in?
Seaport Therapeutics, Inc. (SPTX) operates in the Healthcare sector, specifically the Biotechnology industry (United States).