TRVI

Strong SellSinker

Trevi Therapeutics, Inc. · Healthcare · United States · $1.8B cap · $31.0M/day traded

$12.51 -0.8% · close 26 Oct · scored 27 Oct

Sinker: Weak, expensive and falling. Nothing here to keep it afloat.

20
StockRank
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Quality
39
Value
24
Momentum
38

As of 27 Oct 2026, MoatMap's StockRank for Trevi Therapeutics, Inc. (TRVI) is 20/100, ranked against 24,000+ stocks in 35 markets (Quality 39, Value 24, Momentum 38, each scored against its sector).

Does StockRank work? Each month we publish how every decile did, whichever way it went. See the record →

P/E (TTM)
—
peers 27.2x
ROE
-19.7%
peers -30.5%
D/E
0.0x
peers 0.2x
Dividend %
—
trailing yield

ABOUT TREVI THERAPEUTICS, INC.

Read

Trevi Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on developing therapies for chronic neurological conditions, particularly pruritus (itch) associated with liver and kidney diseases. Its lead candidate, Haduvio (nalbuphine ER), is an oral opioid modulator in late-stage development for pruritus in various indications. Trevi operates as a niche player, addressing significant unmet medical needs in underserved patient populations with chronic pruritic conditions.

FINANCIAL SUMMARY (USD)

Year2022202320242025CAGRTTM2026E2027EFwd CAGR
Revenue0000—————
EPS-0.19-0.14-0.47-0.32—-0.35-0.48-0.58—
Shares142.0M142.0M93.6M128.3M-9.6%142.5M———
Debt9.2M1.3M1.0M0.8M-56.5%0.6M———
Equity107.5M82.5M99.6M183.2M19.5%————
Op CF-28.2M-31.7M-38.3M-42.1M—-52.6M———
Inv CF-107.4M59.4M-21.5M-94.1M—————
Fin CF111.3M-7.9M61.5M121.0M—————
Loading 1Y...
PRICE (1Y) · USD-16.8%
11.912.713.614.415.215 Sep6 Oct26 Oct
SMA 50SMA 200

Price checkNo clear trendExperimental

No clear trend: not near its 52-week low, and not in a steady uptrend.

SwingsVery bumpy

Swung more than 72% of stocks we rank over the past year (58% a year).

How this is worked out

StockRank judges the business. The price check reads only the chart: it is the price side of the Momentum score, in words.

The rules: Still falling is a new 52-week low in the last two weeks, at least 25% below the high. Finding a floor is no new low since. Turning up is 20 or more trading days without a new low, at least 10% off it, and back above a rising 50-day average. In an uptrend is above the 200-day average and within 15% of the high.

In 2,112 US drawdowns since 2001, buying while the price was still falling was followed by a further 20% drop 42% of the time. Waiting for a turn like this one cut that to 33%, at about 7% higher prices and with no better returns. Part of that cut is simply not buying: 13% of falls never turned, and waiting kept those out. Among turns that were bought, 38% still fell another 20%, and 33% of turns were followed by a new low within six months. The benefit was largest in crashes such as 2008 and 2020.

What it measures: day-to-day price moves over the past year, as a yearly figure, ranked against every stock we cover. Very calm under 20% a year, Calm 20 to 30%, Average 30 to 40%, Bumpy 40 to 55%, Very bumpy above that.

What we found: across about 13,500 stocks in 34 markets (2002 to 2025), past swings were a good guide to the next year's, and bumpier stocks fell further. How much further changed too much between eras to put a number on it.

Calm is not safe: a calm stock can still slide steadily.

Rules fixed before any data was fetched. Describes the chart, not a recommendation.

Close
$12.51
RSI (14)
41.0
52-Week Range-38.1% from high
Low $9.82High $20.22

SCORE BREAKDOWN

Quality
39
ROIC
-30.3%24.0
ROE
-19.7%29.7
GP/Assets
—N/A
Op. Margin
0.0%38.6
FCF/Assets
-21.8%21.0
Piotroski
438.6
Int. Cover
—N/A
D/E Ratio
0.00x92.6
Current Ratio
37.28x98.7
Value
24
P/E (TTM)
—N/A
EV/EBITDA
-24.9x25.0
P/FCF
—N/A
P/B
5.6x21.3
P/S
—N/A
Div Yield
—N/A
Momentum
38
52W High %
62%42.8
RS 6M
-19%39.5
SMA 50/200
1.06x69.6
EPS Rev 4W
0.0%51.1
EPS Rev 12W
-3.5%21.9
EPS Improve
-65%8.0
Q Growth
—N/A

FUNDAMENTALS

Market Cap
$1.8B
P/E (Forward)
-21.9x
Gross Margin
—

SECTOR PEERS

Closest peers in Healthcare, ranked by industry match, size, and score similarity. Cross-listings of TRVI are excluded.

TickerCompanyMkt CapStockRankSignal
TRVITrevi Therapeutics, Inc.(you)$1.8B20Strong Sell
TRAXFirst Tracks Biotherapeutics, Inc.$1.6B19Strong Sell
BRVEBraveheart Bio, Inc.$1.9B17Strong Sell
ABSIAbsci Corporation$1.6B21Sell
RXRXRecursion Pharmaceuticals, Inc.$2.0B22Sell
ZBIOZenas BioPharma, Inc.$1.8B15Strong Sell
MLYSMineralys Therapeutics, Inc.$1.8B14Strong Sell
NUVBNuvation Bio Inc.$1.6B23Sell
PVLAPalvella Therapeutics, Inc.$1.8B14Strong Sell
KLRAKailera Therapeutics, Inc.$1.7B15Strong Sell

Peer medians: ROE -30.5% · P/E 27.2x · Gross margin 63.3%

Company Deep Dive

Business segments breakdown, earnings transcript analysis, management credibility scoring, competitive landscape, and scenario modelling.

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Trevi Therapeutics, Inc. (TRVI): Stock Score Summary

Trevi Therapeutics, Inc. (TRVI) has a MoatMap StockRank of 20/100 based on Quality (39/100), Value (24/100), and Momentum (38/100) factor scores. The current signal is STRONG SELL.

Trevi Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on developing therapies for chronic neurological conditions, particularly pruritus (itch) associated with liver and kidney diseases. Its lead candidate, Haduvio (nalbuphine ER), is an oral opioid modulator in late-stage development for pruritus in various indications. Trevi operates as a niche player, addressing significant unmet medical needs in underserved patient populations with chronic pruritic conditions.

Key Financial Metrics

Price$12.51
Market Cap$1.8B
P/E (Forward)-21.85
Price/Book5.59
Return on Equity-19.7%
Return on Invested Capital-30.3%
Debt/Equity0.00x
Operating Margin0.0%
Free Cash Flow$-42M

Trevi Therapeutics, Inc. operates in the Biotechnology industry, part of the Healthcare sector (United States).

Frequently Asked Questions

What is Trevi Therapeutics, Inc.’s (TRVI) StockRank?
MoatMap’s StockRank for Trevi Therapeutics, Inc. (TRVI) is 20/100, with a Strong Sell signal. It is a composite of Quality (39), Value (24), and Momentum (38), each scored against its sector. The composite is then ranked across MoatMap’s universe of 24,000+ stocks.
Does Trevi Therapeutics, Inc. have an economic moat?
Trevi Therapeutics, Inc. (TRVI) has a Quality factor score of 39/100. The Quality factor combines ROIC, Piotroski F-Score, and leverage: the financial fingerprints of a durable competitive advantage. A Quality score above 70 typically indicates a company with the characteristics of a moated business.
Is Trevi Therapeutics, Inc. a buy, hold, or sell?
MoatMap’s current signal for Trevi Therapeutics, Inc. (TRVI) is Strong Sell, based on a StockRank of 20/100. Signals are derived mechanically from the StockRank composite and should be one input among many; combine with your own thesis on management, competitive position, and valuation.
What sector is Trevi Therapeutics, Inc. in?
Trevi Therapeutics, Inc. (TRVI) operates in the Healthcare sector, specifically the Biotechnology industry (United States).