ZVRA

Strong BuyUnloved QualityAI neutral

Zevra Therapeutics, Inc. · Healthcare · United States · $583M cap · $8.4M/day traded

$9.53 -2.9% · close 26 Oct · scored 27 Oct

Unloved Quality: Strong and cheap; the market has not turned yet.

90
StockRank
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Report expected 4 Nov: the next-year EPS estimate has fallen 9.9% over the last 14 weeks.

Quality
87
Value
65
Momentum
41

As of 27 Oct 2026, MoatMap's StockRank for Zevra Therapeutics, Inc. (ZVRA) is 90/100, ranked against 24,000+ stocks in 35 markets (Quality 87, Value 65, Momentum 41, each scored against its sector).

Does StockRank work? Each month we publish how every decile did, whichever way it went. See the record →

P/E (TTM)
10.7x
peers 27.3x
ROE
34.8%
peers -30.5%
D/E
0.0x
peers 0.2x
Dividend %
—
trailing yield
AI CONVICTION THESIS

Zevra Therapeutics sells MIPLYFFA, an approved treatment for the ultra-rare Niemann-Pick disease type C. Revenue rose 53% in the latest quarter, and the company is presenting long-term real-world data. Consensus estimates were revised up 2.5%. As a single-product rare-disease company, its outlook depends on patient identification, payer access and pipeline progress. Insider selling has been small.

ABOUT ZEVRA THERAPEUTICS, INC.

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Zevra Therapeutics, Inc. is a rare disease therapeutics company dedicated to developing and commercializing novel treatments for patients with unmet medical needs, particularly focusing on neurological and endocrine disorders. The company strategically targets highly specialized, underserved patient populations, leveraging orphan drug designations to create a competitive advantage. Zevra is focused on advancing late-stage clinical candidates and commercializing treatments that address significant gaps in care for rare diseases.

FINANCIAL SUMMARY (USD)

Year2022202320242025CAGRTTM2026E2027EFwd CAGR
Revenue10.2M27.5M23.6M106.5M118.8%136.1M153.3M177.7M29.2%
EPS-1.20-1.30-2.281.35—0.921.171.08-10.7%
Shares34.5M41.5M53.7M56.9M+64.6%59.4M———
Debt14.1M43.8M60.3M63.2M64.8%————
Equity75.1M61.9M39.7M154.7M27.2%————
Op CF-18.7M-33.5M-69.7M-1.6M—33.4M———
Inv CF-36.7M-17.4M-22.2M18.1M—————
Fin CF8.4M28.5M82.1M12.1M—————
Loading 1Y...
PRICE (1Y) · USD-18.2%
9.510.110.711.311.815 Sep6 Oct26 Oct
SMA 50SMA 200

Price checkNo clear trendExperimental

No clear trend: not near its 52-week low, and not in a steady uptrend.

SwingsVery bumpy

Swung more than 75% of stocks we rank over the past year (60% a year).

How this is worked out

StockRank judges the business. The price check reads only the chart: it is the price side of the Momentum score, in words.

The rules: Still falling is a new 52-week low in the last two weeks, at least 25% below the high. Finding a floor is no new low since. Turning up is 20 or more trading days without a new low, at least 10% off it, and back above a rising 50-day average. In an uptrend is above the 200-day average and within 15% of the high.

In 2,112 US drawdowns since 2001, buying while the price was still falling was followed by a further 20% drop 42% of the time. Waiting for a turn like this one cut that to 33%, at about 7% higher prices and with no better returns. Part of that cut is simply not buying: 13% of falls never turned, and waiting kept those out. Among turns that were bought, 38% still fell another 20%, and 33% of turns were followed by a new low within six months. The benefit was largest in crashes such as 2008 and 2020.

What it measures: day-to-day price moves over the past year, as a yearly figure, ranked against every stock we cover. Very calm under 20% a year, Calm 20 to 30%, Average 30 to 40%, Bumpy 40 to 55%, Very bumpy above that.

What we found: across about 13,500 stocks in 34 markets (2002 to 2025), past swings were a good guide to the next year's, and bumpier stocks fell further. How much further changed too much between eras to put a number on it.

Calm is not safe: a calm stock can still slide steadily.

Rules fixed before any data was fetched. Describes the chart, not a recommendation.

Close
$9.53
RSI (14)
34.3
52-Week Range-36.6% from high
Low $8.01High $15.03

SCORE BREAKDOWN

Quality
87
ROIC
30.6%96.3
ROE
34.8%95.5
GP/Assets
45.6%84.5
Op. Margin
42.3%97.2
FCF/Assets
17.0%94.9
Piotroski
667.9
Int. Cover
13.1x65.9
D/E Ratio
0.01x86.8
Current Ratio
5.17x73.3
Value
65
P/E (TTM)
10.7x86.4
EV/EBITDA
8.9x72.9
P/FCF
12.0x76.2
P/B
2.7x47.0
P/S
4.3x43.2
Div Yield
—N/A
Momentum
41
52W High %
63%45.0
RS 6M
-10%51.4
SMA 50/200
1.05x69.4
EPS Rev 4W
0.0%51.1
EPS Rev 12W
-9.9%12.7
EPS Improve
+17%32.1
Q Growth
-88%2.9

FUNDAMENTALS

Market Cap
$583M
P/E (Forward)
9.1x
Gross Margin
95.5%

SECTOR PEERS

Closest peers in Healthcare, ranked by industry match, size, and score similarity. Cross-listings of ZVRA are excluded.

TickerCompanyMkt CapStockRankSignal
ZVRAZevra Therapeutics, Inc.(you)$583M90Strong Buy
PBYIPuma Biotechnology, Inc.$569M97Strong Buy
CRMDCorMedix Inc.$612M98Strong Buy
ABUSArbutus Biopharma Corporation$644M81Strong Buy
1521.HKFrontage Holdings Corporation$387M94Strong Buy
RIGLRigel Pharmaceuticals, Inc.$899M98Strong Buy
QTTBQ32 Bio Inc.$258M88Strong Buy
INVAInnoviva, Inc.$1.5B93Strong Buy
PLXProtalix BioTherapeutics, Inc.$205M98Strong Buy
MDXGMiMedx Group, Inc.$571M62Hold

Peer medians: ROE -30.5% · P/E 27.3x · Gross margin 63.3%

Company Deep Dive

Business segments breakdown, earnings transcript analysis, management credibility scoring, competitive landscape, and scenario modelling.

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Zevra Therapeutics, Inc. (ZVRA): Stock Score Summary

Zevra Therapeutics, Inc. (ZVRA) has a MoatMap StockRank of 90/100 based on Quality (87/100), Value (65/100), and Momentum (41/100) factor scores. The current signal is STRONG BUY. Zevra Therapeutics sells MIPLYFFA, an approved treatment for the ultra-rare Niemann-Pick disease type C. Revenue rose 53% in the latest quarter, and the company is presenting long-term real-world data. Consensus estimates were revised up 2.5%. As a single-product rare-disease company, its outlook depends on patient identification, payer access and pipeline progress. Insider selling has been small.

Zevra Therapeutics, Inc. is a rare disease therapeutics company dedicated to developing and commercializing novel treatments for patients with unmet medical needs, particularly focusing on neurological and endocrine disorders. The company strategically targets highly specialized, underserved patient populations, leveraging orphan drug designations to create a competitive advantage. Zevra is focused on advancing late-stage clinical candidates and commercializing treatments that address significant gaps in care for rare diseases.

Key Financial Metrics

Price$9.53
Market Cap$583M
P/E (TTM)10.66
P/E (Forward)9.11
Price/Book2.67
Return on Equity34.8%
Return on Invested Capital30.6%
Debt/Equity0.01x
Gross Margin95.5%
Operating Margin42.3%
Revenue Growth53.3%
Free Cash Flow$48M

Zevra Therapeutics, Inc. operates in the Biotechnology industry, part of the Healthcare sector (United States).

Frequently Asked Questions

What is Zevra Therapeutics, Inc.’s (ZVRA) StockRank?
MoatMap’s StockRank for Zevra Therapeutics, Inc. (ZVRA) is 90/100, with a Strong Buy signal. It is a composite of Quality (87), Value (65), and Momentum (41), each scored against its sector. The composite is then ranked across MoatMap’s universe of 24,000+ stocks.
Does Zevra Therapeutics, Inc. have an economic moat?
Zevra Therapeutics, Inc. (ZVRA) has a Quality factor score of 87/100. The Quality factor combines ROIC, Piotroski F-Score, and leverage: the financial fingerprints of a durable competitive advantage. A Quality score above 70 typically indicates a company with the characteristics of a moated business.
Is Zevra Therapeutics, Inc. a buy, hold, or sell?
MoatMap’s current signal for Zevra Therapeutics, Inc. (ZVRA) is Strong Buy, based on a StockRank of 90/100. Signals are derived mechanically from the StockRank composite and should be one input among many; combine with your own thesis on management, competitive position, and valuation.
What sector is Zevra Therapeutics, Inc. in?
Zevra Therapeutics, Inc. (ZVRA) operates in the Healthcare sector, specifically the Biotechnology industry (United States).