ANAB

SellFallen Favourite

AnaptysBio, Inc. · Healthcare · United States · $1.5B cap · $27.8M/day traded

$48.77 +0.1% · close 26 Oct · scored 27 Oct

StockRank down 2.0 since 24 Oct: Momentum down 3.

Fallen Favourite: A good business, still expensive, and the price is falling.

30
StockRank
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Quality
57
Value
20
Momentum
41

As of 27 Oct 2026, MoatMap's StockRank for AnaptysBio, Inc. (ANAB) is 30/100, ranked against 24,000+ stocks in 35 markets (Quality 57, Value 20, Momentum 41, each scored against its sector).

Does StockRank work? Each month we publish how every decile did, whichever way it went. See the record →

P/E (TTM)
—
peers 27.2x
ROE
-35.6%
peers -30.1%
D/E
25.5x
peers 0.2x
Dividend %
—
trailing yield

ABOUT ANAPTYSBIO, INC.

Read

AnaptysBio, Inc. is a clinical-stage biotechnology company focused on discovering and developing therapeutic antibodies for inflammatory and immuno-oncology diseases. Its competitive moat stems from its proprietary SHM-P antibody discovery platform, which enables rapid generation of highly potent and selective therapeutic candidates. The company is a specialized player in biopharmaceutical innovation, aiming to address significant unmet medical needs.

FINANCIAL SUMMARY (USD)

Year2022202320242025CAGRTTM2027E2028EFwd CAGR
Revenue10.3M17.2M91.3M234.6M183.6%106.1M101.1M171.3M-10.0%
EPS-4.57-6.08-5.12-0.46—-0.96-0.234.35—
Shares28.5M26.6M30.5M28.0M-1.7%29.9M———
Debt19.4M17.8M16.0M14.1M-10.1%————
Equity262.1M88.1M70.9M37.2M-47.8%————
Op CF-73.6M-120.8M-135.3M19.7M—-105.1M———
Inv CF-394.8M144.8M95.4M228.0M—————
Fin CF44.0M-59.3M127.1M-132.6M—————
Loading 1Y...
PRICE (1Y) · USD-10.8%
45.447.950.352.855.215 Sep6 Oct26 Oct
SMA 50SMA 200

Price checkNo clear trendExperimental

No clear trend: not near its 52-week low, and not in a steady uptrend.

SwingsVery bumpy

Swung more than 77% of stocks we rank over the past year (63% a year).

How this is worked out

StockRank judges the business. The price check reads only the chart: it is the price side of the Momentum score, in words.

The rules: Still falling is a new 52-week low in the last two weeks, at least 25% below the high. Finding a floor is no new low since. Turning up is 20 or more trading days without a new low, at least 10% off it, and back above a rising 50-day average. In an uptrend is above the 200-day average and within 15% of the high.

In 2,112 US drawdowns since 2001, buying while the price was still falling was followed by a further 20% drop 42% of the time. Waiting for a turn like this one cut that to 33%, at about 7% higher prices and with no better returns. Part of that cut is simply not buying: 13% of falls never turned, and waiting kept those out. Among turns that were bought, 38% still fell another 20%, and 33% of turns were followed by a new low within six months. The benefit was largest in crashes such as 2008 and 2020.

What it measures: day-to-day price moves over the past year, as a yearly figure, ranked against every stock we cover. Very calm under 20% a year, Calm 20 to 30%, Average 30 to 40%, Bumpy 40 to 55%, Very bumpy above that.

What we found: across about 13,500 stocks in 34 markets (2002 to 2025), past swings were a good guide to the next year's, and bumpier stocks fell further. How much further changed too much between eras to put a number on it.

Calm is not safe: a calm stock can still slide steadily.

Rules fixed before any data was fetched. Describes the chart, not a recommendation.

Close
$48.77
RSI (14)
52.4
52-Week Range-32.6% from high
Low $20.18High $72.36

SCORE BREAKDOWN

Quality
57
ROIC
17.2%86.6
ROE
-35.6%23.1
GP/Assets
30.6%66.1
Op. Margin
53.4%98.6
FCF/Assets
n/mN/A
Piotroski
559.2
Int. Cover
0.7x37.8
D/E Ratio
25.47x0.3
Current Ratio
5.61x75.7
Value
20
P/E (TTM)
—N/A
EV/EBITDA
23.8x26.2
P/FCF
n/mN/A
P/B
136.9x0.4
P/S
13.7x19.2
Div Yield
—N/A
Momentum
41
52W High %
67%51.7
RS 6M
-34%23.4
SMA 50/200
1.05x68.4
EPS Rev 4W
-13.3%3.2
EPS Rev 12W
-13.3%10.3
EPS Improve
+573%96.3
Q Growth
—N/A

FUNDAMENTALS

Market Cap
$1.5B
P/E (Forward)
10.7x
Gross Margin
105.0%

SECTOR PEERS

Closest peers in Healthcare, ranked by industry match, size, and score similarity. Cross-listings of ANAB are excluded.

TickerCompanyMkt CapStockRankSignal
ANABAnaptysBio, Inc.(you)$1.5B30Sell
KRSAKorsana Biosciences, Inc.$1.4B31Sell
NVAXNovavax, Inc.$1.6B33Sell
VIRVir Biotechnology, Inc.$1.8B33Sell
URGNUroGen Pharma Ltd.$1.7B35Sell
VORVor Biopharma Inc.$1.1B27Sell
XNCRXencor, Inc.$1.9B26Sell
MNKDMannKind Corporation$1.0B32Sell
NUVBNuvation Bio Inc.$1.6B23Sell
AGIOAgios Pharmaceuticals, Inc.$2.2B29Sell

Peer medians: ROE -30.1% · P/E 27.2x · Gross margin 63.3%

Company Deep Dive

Business segments breakdown, earnings transcript analysis, management credibility scoring, competitive landscape, and scenario modelling.

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AnaptysBio, Inc. (ANAB): Stock Score Summary

AnaptysBio, Inc. (ANAB) has a MoatMap StockRank of 30/100 based on Quality (57/100), Value (20/100), and Momentum (41/100) factor scores. The current signal is SELL.

AnaptysBio, Inc. is a clinical-stage biotechnology company focused on discovering and developing therapeutic antibodies for inflammatory and immuno-oncology diseases. Its competitive moat stems from its proprietary SHM-P antibody discovery platform, which enables rapid generation of highly potent and selective therapeutic candidates. The company is a specialized player in biopharmaceutical innovation, aiming to address significant unmet medical needs.

Key Financial Metrics

Price$48.77
Market Cap$1.5B
P/E (Forward)10.74
Price/Book136.88
Return on Equity-35.6%
Return on Invested Capital17.2%
Debt/Equity25.47x
Gross Margin105.0%
Operating Margin53.4%
Revenue Growth23.5%
Free Cash Flow$4M

AnaptysBio, Inc. operates in the Biotechnology industry, part of the Healthcare sector (United States).

Frequently Asked Questions

What is AnaptysBio, Inc.’s (ANAB) StockRank?
MoatMap’s StockRank for AnaptysBio, Inc. (ANAB) is 30/100, with a Sell signal. It is a composite of Quality (57), Value (20), and Momentum (41), each scored against its sector. The composite is then ranked across MoatMap’s universe of 24,000+ stocks.
Does AnaptysBio, Inc. have an economic moat?
AnaptysBio, Inc. (ANAB) has a Quality factor score of 57/100. The Quality factor combines ROIC, Piotroski F-Score, and leverage: the financial fingerprints of a durable competitive advantage. A Quality score above 70 typically indicates a company with the characteristics of a moated business.
Is AnaptysBio, Inc. a buy, hold, or sell?
MoatMap’s current signal for AnaptysBio, Inc. (ANAB) is Sell, based on a StockRank of 30/100. Signals are derived mechanically from the StockRank composite and should be one input among many; combine with your own thesis on management, competitive position, and valuation.
What sector is AnaptysBio, Inc. in?
AnaptysBio, Inc. (ANAB) operates in the Healthcare sector, specifically the Biotechnology industry (United States).