BCRX

BuyFull HouseAI neutral

BioCryst Pharmaceuticals, Inc. · Healthcare · United States · $2.0B cap · $42.8M/day traded

$7.88 +3.0% · close 26 Oct · scored 27 Oct

StockRank down 4.5 since 24 Oct: Momentum down 5.

Full House: Strong business, sensible price, market agrees. The rare full house.

74
StockRank
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Quality
59
Value
59
Momentum
51

As of 27 Oct 2026, MoatMap's StockRank for BioCryst Pharmaceuticals, Inc. (BCRX) is 74/100, ranked against 24,000+ stocks in 35 markets (Quality 59, Value 59, Momentum 51, each scored against its sector).

Does StockRank work? Each month we publish how every decile did, whichever way it went. See the record →

P/E (TTM)
—
peers 27.2x
ROE
—
peers -30.2%
D/E
—
peers 0.2x
Dividend %
—
trailing yield
AI CONVICTION THESIS

BioCryst sells Orladeyo, an oral preventive treatment for hereditary angioedema that now generates meaningful cash. Its management says it wants to use that cash to buy another asset. The stock fell after a trial result in a related swelling disease, and RBC Capital describes a challenging near-term outlook as injectable and newer oral competitors enter the market. Future value depends on whether Orladeyo can hold share and whether an acquisition is priced sensibly, and neither is visible yet.

ABOUT BIOCRYST PHARMACEUTICALS, INC.

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BioCryst Pharmaceuticals, Inc. is a biopharmaceutical company focused on discovering, developing, and commercializing oral, small-molecule medicines for patients with rare diseases. Its competitive moat is anchored by ORLADEYO, a proprietary oral drug offering a differentiated and convenient treatment for hereditary angioedema (HAE). BioCryst leverages its expertise in small-molecule drug development to address high unmet needs in niche patient populations.

FINANCIAL SUMMARY (USD)

Year2022202320242025CAGRTTM2026E2027EFwd CAGR
Revenue270.8M331.4M450.7M874.8M47.8%940.6M710.1M736.5M-8.2%
EPS-1.33-1.18-0.431.26—-1.401.491.6414.0%
Shares187.9M205.8M208.5M213.1M+13.4%255.5M———
Debt741.5M825.1M808.7M438.9M-16.0%836.6M———
Equity-294.6M-455.5M-475.9M-119.2M—————
Op CF-161.8M-95.1M-52.0M347.4M—376.1M———
Inv CF-128.2M-131.5M52.6M-13.7M—————
Fin CF88.0M32.5M-5.8M-349.9M—————
Loading 1Y...
PRICE (1Y) · USD-3.4%
7.77.98.28.58.815 Sep6 Oct26 Oct
SMA 50SMA 200

Price checkNo clear trendExperimental

No clear trend: not near its 52-week low, and not in a steady uptrend.

SwingsBumpy

Swung more than 60% of stocks we rank over the past year (48% a year).

How this is worked out

StockRank judges the business. The price check reads only the chart: it is the price side of the Momentum score, in words.

The rules: Still falling is a new 52-week low in the last two weeks, at least 25% below the high. Finding a floor is no new low since. Turning up is 20 or more trading days without a new low, at least 10% off it, and back above a rising 50-day average. In an uptrend is above the 200-day average and within 15% of the high.

In 2,112 US drawdowns since 2001, buying while the price was still falling was followed by a further 20% drop 42% of the time. Waiting for a turn like this one cut that to 33%, at about 7% higher prices and with no better returns. Part of that cut is simply not buying: 13% of falls never turned, and waiting kept those out. Among turns that were bought, 38% still fell another 20%, and 33% of turns were followed by a new low within six months. The benefit was largest in crashes such as 2008 and 2020.

What it measures: day-to-day price moves over the past year, as a yearly figure, ranked against every stock we cover. Very calm under 20% a year, Calm 20 to 30%, Average 30 to 40%, Bumpy 40 to 55%, Very bumpy above that.

What we found: across about 13,500 stocks in 34 markets (2002 to 2025), past swings were a good guide to the next year's, and bumpier stocks fell further. How much further changed too much between eras to put a number on it.

Calm is not safe: a calm stock can still slide steadily.

Rules fixed before any data was fetched. Describes the chart, not a recommendation.

Close
$7.88
RSI (14)
48.6
52-Week Range-29.8% from high
Low $6.23High $11.22

SCORE BREAKDOWN

Quality
59
ROIC
-96.2%6.9
ROE
—N/A
GP/Assets
141.6%99.5
Op. Margin
45.1%97.6
FCF/Assets
72.6%99.5
Piotroski
783.3
Int. Cover
-4.1x28.2
D/E Ratio
—N/A
Current Ratio
2.32x46.0
Value
59
P/E (TTM)
—N/A
EV/EBITDA
5.6x89.6
P/FCF
5.2x92.3
P/B
-4.3x25.0
P/S
2.1x65.1
Div Yield
—N/A
Momentum
51
52W High %
70%56.1
RS 6M
-18%40.3
SMA 50/200
1.00x58.5
EPS Rev 4W
-12.2%3.4
EPS Rev 12W
-17.5%7.8
EPS Improve
+159%83.7
Q Growth
1442%98.8

FUNDAMENTALS

Market Cap
$2.0B
P/E (Forward)
9.3x
Gross Margin
77.4%

SECTOR PEERS

Closest peers in Healthcare, ranked by industry match, size, and score similarity. Cross-listings of BCRX are excluded.

TickerCompanyMkt CapStockRankSignal
BCRXBioCryst Pharmaceuticals, Inc.(you)$2.0B74Buy
TRLVTrulieve Cannabis Corp.$2.0B80Buy
PBHPrestige Consumer Healthcare Inc.$2.3B68Buy
PAHCPhibro Animal Health Corporation$1.6B63Hold
ANIPANI Pharmaceuticals, Inc.$1.7B89Strong Buy
XERSXeris Biopharma Holdings, Inc.$1.9B55Hold
ETONEton Pharmaceuticals, Inc.$1.4B59Hold
PCRXPacira BioSciences, Inc.$1.5B90Strong Buy
GTII.CNGreen Thumb Industries Inc.$1.4B89Strong Buy
COLLCollegium Pharmaceutical, Inc.$747M82Strong Buy

Peer medians: ROE -30.2% · P/E 27.2x · Gross margin 63.3%

Company Deep Dive

Business segments breakdown, earnings transcript analysis, management credibility scoring, competitive landscape, and scenario modelling.

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BioCryst Pharmaceuticals, Inc. (BCRX): Stock Score Summary

BioCryst Pharmaceuticals, Inc. (BCRX) has a MoatMap StockRank of 74/100 based on Quality (59/100), Value (59/100), and Momentum (51/100) factor scores. The current signal is BUY. BioCryst sells Orladeyo, an oral preventive treatment for hereditary angioedema that now generates meaningful cash. Its management says it wants to use that cash to buy another asset. The stock fell after a trial result in a related swelling disease, and RBC Capital describes a challenging near-term outlook as injectable and newer oral competitors enter the market. Future value depends on whether Orladeyo can hold share and whether an acquisition is priced sensibly, and neither is visible yet.

BioCryst Pharmaceuticals, Inc. is a biopharmaceutical company focused on discovering, developing, and commercializing oral, small-molecule medicines for patients with rare diseases. Its competitive moat is anchored by ORLADEYO, a proprietary oral drug offering a differentiated and convenient treatment for hereditary angioedema (HAE). BioCryst leverages its expertise in small-molecule drug development to address high unmet needs in niche patient populations.

Key Financial Metrics

Price$7.88
Market Cap$2.0B
P/E (Forward)9.27
Price/Book-4.30
Return on Invested Capital-96.2%
Gross Margin77.4%
Operating Margin45.1%
Revenue Growth33.6%
Free Cash Flow$373M

BioCryst Pharmaceuticals, Inc. operates in the Drug Manufacturers - Specialty & Generic industry, part of the Healthcare sector (United States).

Frequently Asked Questions

What is BioCryst Pharmaceuticals, Inc.’s (BCRX) StockRank?
MoatMap’s StockRank for BioCryst Pharmaceuticals, Inc. (BCRX) is 74/100, with a Buy signal. It is a composite of Quality (59), Value (59), and Momentum (51), each scored against its sector. The composite is then ranked across MoatMap’s universe of 24,000+ stocks.
Does BioCryst Pharmaceuticals, Inc. have an economic moat?
BioCryst Pharmaceuticals, Inc. (BCRX) has a Quality factor score of 59/100. The Quality factor combines ROIC, Piotroski F-Score, and leverage: the financial fingerprints of a durable competitive advantage. A Quality score above 70 typically indicates a company with the characteristics of a moated business.
Is BioCryst Pharmaceuticals, Inc. a buy, hold, or sell?
MoatMap’s current signal for BioCryst Pharmaceuticals, Inc. (BCRX) is Buy, based on a StockRank of 74/100. Signals are derived mechanically from the StockRank composite and should be one input among many; combine with your own thesis on management, competitive position, and valuation.
What sector is BioCryst Pharmaceuticals, Inc. in?
BioCryst Pharmaceuticals, Inc. (BCRX) operates in the Healthcare sector, specifically the Drug Manufacturers - Specialty & Generic industry (United States).