XERS

HoldPremium Grower

Xeris Biopharma Holdings, Inc. · Healthcare · United States · $1.9B cap · $31.3M/day traded

$10.21 +0.1% · close 26 Oct · scored 27 Oct

StockRank down 1.8 since 24 Oct.

Premium Grower: Strong business with the market behind it, priced at a premium.

55
StockRank
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Report expected 5 Nov: the next-year EPS estimate has fallen 49.9% over the last 14 weeks.

Quality
59
Value
26
Momentum
65

As of 27 Oct 2026, MoatMap's StockRank for Xeris Biopharma Holdings, Inc. (XERS) is 55/100, ranked against 24,000+ stocks in 35 markets (Quality 59, Value 26, Momentum 65, each scored against its sector).

Does StockRank work? Each month we publish how every decile did, whichever way it went. See the record →

P/E (TTM)
—
peers 27.2x
ROE
4.0%
peers -30.5%
D/E
18.9x
peers 0.2x
Dividend %
—
trailing yield

ABOUT XERIS BIOPHARMA HOLDINGS, INC.

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Xeris Biopharma Holdings, Inc. is a specialty pharmaceutical company leveraging its proprietary XeriSol and XeriJect formulation technologies to develop ready-to-use liquid injectables. These platforms eliminate the need for reconstitution, offering a distinct competitive advantage in patient convenience and adherence. The company operates as a niche player focused on endocrine, metabolic, and neurological conditions.

FINANCIAL SUMMARY (USD)

Year2022202320242025CAGRTTM2026E2027EFwd CAGR
Revenue110.2M163.9M203.1M291.8M38.3%335.4M387.9M480.0M28.2%
EPS-0.70-0.45-0.370.00—-0.10-0.090.20—
Shares136.3M138.1M149.4M166.2M+22.0%182.3M———
Debt198.1M229.2M271.4M258.1M9.2%289.4M———
Equity45.2M-6.8M-29.6M13.7M-32.8%————
Op CF-102.9M-47.0M-37.0M28.6M—56.6M———
Inv CF34.5M-6.0M4.9M-0.7M—————
Fin CF127.5M-1.6M36.2M11.4M—————
Loading 1Y...
PRICE (1Y) · USD+36.3%
7.58.49.310.211.115 Sep6 Oct26 Oct
SMA 50SMA 200

Price checkIn an uptrendExperimental

Above its 200-day average and 11% below its 52-week high.

SwingsBumpy

Swung more than 68% of stocks we rank over the past year (54% a year).

How this is worked out

StockRank judges the business. The price check reads only the chart: it is the price side of the Momentum score, in words.

The rules: Still falling is a new 52-week low in the last two weeks, at least 25% below the high. Finding a floor is no new low since. Turning up is 20 or more trading days without a new low, at least 10% off it, and back above a rising 50-day average. In an uptrend is above the 200-day average and within 15% of the high.

In 2,112 US drawdowns since 2001, buying while the price was still falling was followed by a further 20% drop 42% of the time. Waiting for a turn like this one cut that to 33%, at about 7% higher prices and with no better returns. Part of that cut is simply not buying: 13% of falls never turned, and waiting kept those out. Among turns that were bought, 38% still fell another 20%, and 33% of turns were followed by a new low within six months. The benefit was largest in crashes such as 2008 and 2020.

What it measures: day-to-day price moves over the past year, as a yearly figure, ranked against every stock we cover. Very calm under 20% a year, Calm 20 to 30%, Average 30 to 40%, Bumpy 40 to 55%, Very bumpy above that.

What we found: across about 13,500 stocks in 34 markets (2002 to 2025), past swings were a good guide to the next year's, and bumpier stocks fell further. How much further changed too much between eras to put a number on it.

Calm is not safe: a calm stock can still slide steadily.

Rules fixed before any data was fetched. Describes the chart, not a recommendation.

Close
$10.21
RSI (14)
52.0
52-Week Range-10.6% from high
Low $5.25High $11.42

SCORE BREAKDOWN

Quality
59
ROIC
4.0%52.9
ROE
4.0%25.0
GP/Assets
75.7%95.8
Op. Margin
5.6%54.3
FCF/Assets
14.5%93.0
Piotroski
893.5
Int. Cover
0.4x36.8
D/E Ratio
18.85x0.7
Current Ratio
1.45x24.9
Value
26
P/E (TTM)
—N/A
EV/EBITDA
41.6x13.2
P/FCF
33.4x37.3
P/B
-182.1x25.0
P/S
5.5x37.0
Div Yield
—N/A
Momentum
65
52W High %
89%84.9
RS 6M
60%93.8
SMA 50/200
1.23x90.7
EPS Rev 4W
-49.6%0.7
EPS Rev 12W
-49.9%1.6
EPS Improve
+297%92.0
Q Growth
—N/A

FUNDAMENTALS

Market Cap
$1.9B
P/E (Forward)
51.9x
Gross Margin
86.6%

SECTOR PEERS

Closest peers in Healthcare, ranked by industry match, size, and score similarity. Cross-listings of XERS are excluded.

TickerCompanyMkt CapStockRankSignal
XERSXeris Biopharma Holdings, Inc.(you)$1.9B55Hold
ETONEton Pharmaceuticals, Inc.$1.4B59Hold
PAHCPhibro Animal Health Corporation$1.6B63Hold
PBHPrestige Consumer Healthcare Inc.$2.3B68Buy
BCRXBioCryst Pharmaceuticals, Inc.$2.0B74Buy
LQDALiquidia Corporation$3.8B46Hold
CURA.TOCuraleaf Holdings, Inc.$2.1B33Sell
SUPNSupernus Pharmaceuticals, Inc.$2.4B35Hold
TRLVTrulieve Cannabis Corp.$2.0B80Buy
EOLSEvolus, Inc.$463M48Hold

Peer medians: ROE -30.5% · P/E 27.2x · Gross margin 63.3%

Company Deep Dive

Business segments breakdown, earnings transcript analysis, management credibility scoring, competitive landscape, and scenario modelling.

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Xeris Biopharma Holdings, Inc. (XERS): Stock Score Summary

Xeris Biopharma Holdings, Inc. (XERS) has a MoatMap StockRank of 55/100 based on Quality (59/100), Value (26/100), and Momentum (65/100) factor scores. The current signal is HOLD.

Xeris Biopharma Holdings, Inc. is a specialty pharmaceutical company leveraging its proprietary XeriSol and XeriJect formulation technologies to develop ready-to-use liquid injectables. These platforms eliminate the need for reconstitution, offering a distinct competitive advantage in patient convenience and adherence. The company operates as a niche player focused on endocrine, metabolic, and neurological conditions.

Key Financial Metrics

Price$10.21
Market Cap$1.9B
P/E (Forward)51.86
Price/Book-182.14
Return on Equity4.0%
Return on Invested Capital4.0%
Debt/Equity18.85x
Gross Margin86.6%
Operating Margin5.6%
Revenue Growth28.7%
Free Cash Flow$56M

Xeris Biopharma Holdings, Inc. operates in the Drug Manufacturers - Specialty & Generic industry, part of the Healthcare sector (United States).

Frequently Asked Questions

What is Xeris Biopharma Holdings, Inc.’s (XERS) StockRank?
MoatMap’s StockRank for Xeris Biopharma Holdings, Inc. (XERS) is 55/100, with a Hold signal. It is a composite of Quality (59), Value (26), and Momentum (65), each scored against its sector. The composite is then ranked across MoatMap’s universe of 24,000+ stocks.
Does Xeris Biopharma Holdings, Inc. have an economic moat?
Xeris Biopharma Holdings, Inc. (XERS) has a Quality factor score of 59/100. The Quality factor combines ROIC, Piotroski F-Score, and leverage: the financial fingerprints of a durable competitive advantage. A Quality score above 70 typically indicates a company with the characteristics of a moated business.
Is Xeris Biopharma Holdings, Inc. a buy, hold, or sell?
MoatMap’s current signal for Xeris Biopharma Holdings, Inc. (XERS) is Hold, based on a StockRank of 55/100. Signals are derived mechanically from the StockRank composite and should be one input among many; combine with your own thesis on management, competitive position, and valuation.
What sector is Xeris Biopharma Holdings, Inc. in?
Xeris Biopharma Holdings, Inc. (XERS) operates in the Healthcare sector, specifically the Drug Manufacturers - Specialty & Generic industry (United States).