BCYC

Strong SellSinker

Bicycle Therapeutics plc · Healthcare · United Kingdom · $248M cap · $1.7M/day traded

$3.65 +2.8% · close 26 Oct · scored 27 Oct

StockRank up 2.6 since 24 Oct: Momentum up 5 after a 3% price rise.

Sinker: Weak, expensive and falling. Nothing here to keep it afloat.

15
StockRank
Get score and insider alerts
Quality
24
Value
38
Momentum
31

As of 27 Oct 2026, MoatMap's StockRank for Bicycle Therapeutics plc (BCYC) is 15/100, ranked against 24,000+ stocks in 35 markets (Quality 24, Value 38, Momentum 31, each scored against its sector).

Does StockRank work? Each month we publish how every decile did, whichever way it went. See the record →

P/E (TTM)
—
peers 24.1x
ROE
-32.3%
peers -4.5%
D/E
0.0x
peers 0.2x
Dividend %
—
trailing yield

ABOUT BICYCLE THERAPEUTICS PLC

Read

Bicycle Therapeutics plc is a clinical-stage biopharmaceutical company pioneering a novel class of medicines called Bicycles®, which are synthetic short peptides with unique therapeutic properties. The company leverages its proprietary Bicycle® platform to develop highly selective and potent small-molecule-like biologics for oncology and other therapeutic areas. This innovative drug modality aims to address difficult-to-drug targets and improve patient outcomes.

FINANCIAL SUMMARY (USD)

Year2022202320242025CAGRTTM2026E2027EFwd CAGR
Revenue14.5M27.0M35.3M72.6M71.2%61.2M17.5M6.7M-69.6%
EPS-3.80-5.08-2.90-3.16—-2.73-2.45-2.21—
Shares29.9M42.4M69.1M69.4M+132.2%————
Debt44.3M45.0M9.5M16.9M-27.6%14.7M———
Equity270.8M370.9M793.1M610.0M31.1%————
Op CF-86.1M-60.6M-164.7M-249.7M—-206.1M———
Inv CF-19.0M-2.9M-1.2M-2.4M—————
Fin CF6.7M250.0M519.8M-0.1M—————
Loading 1Y...
PRICE (1Y) · USD-0.5%
3.43.53.73.94.015 Sep6 Oct26 Oct
SMA 50SMA 200

Price checkFinding a floorExperimental

No new 52-week low for 3 weeks, 10% above that low, but not back above a rising 50-day average.

SwingsBumpy

Swung more than 67% of stocks we rank over the past year (53% a year).

How this is worked out

StockRank judges the business. The price check reads only the chart: it is the price side of the Momentum score, in words.

The rules: Still falling is a new 52-week low in the last two weeks, at least 25% below the high. Finding a floor is no new low since. Turning up is 20 or more trading days without a new low, at least 10% off it, and back above a rising 50-day average. In an uptrend is above the 200-day average and within 15% of the high.

In 2,112 US drawdowns since 2001, buying while the price was still falling was followed by a further 20% drop 42% of the time. Waiting for a turn like this one cut that to 33%, at about 7% higher prices and with no better returns. Part of that cut is simply not buying: 13% of falls never turned, and waiting kept those out. Among turns that were bought, 38% still fell another 20%, and 33% of turns were followed by a new low within six months. The benefit was largest in crashes such as 2008 and 2020.

What it measures: day-to-day price moves over the past year, as a yearly figure, ranked against every stock we cover. Very calm under 20% a year, Calm 20 to 30%, Average 30 to 40%, Bumpy 40 to 55%, Very bumpy above that.

What we found: across about 13,500 stocks in 34 markets (2002 to 2025), past swings were a good guide to the next year's, and bumpier stocks fell further. How much further changed too much between eras to put a number on it.

Calm is not safe: a calm stock can still slide steadily.

Rules fixed before any data was fetched. Describes the chart, not a recommendation.

Close
$3.65
RSI (14)
44.4
52-Week Range-59.8% from high
Low $3.33High $9.08

SCORE BREAKDOWN

Quality
24
ROIC
-28.5%24.6
ROE
-32.3%24.2
GP/Assets
-17.8%4.7
Op. Margin
-8673.9%2.3
FCF/Assets
-29.0%15.6
Piotroski
12.3
Int. Cover
-50.0x5.8
D/E Ratio
0.03x76.9
Current Ratio
12.08x90.0
Value
38
P/E (TTM)
—N/A
EV/EBITDA
1.2x25.0
P/FCF
—N/A
P/B
0.5x95.5
P/S
4.1x45.0
Div Yield
—N/A
Momentum
31
52W High %
40%17.0
RS 6M
-30%26.2
SMA 50/200
0.84x19.8
EPS Rev 4W
+0.5%77.5
EPS Rev 12W
-0.5%31.4
EPS Improve
+19%33.2
Q Growth
—N/A

FUNDAMENTALS

Market Cap
$248M
P/E (Forward)
-1.6x
Gross Margin
—

SECTOR PEERS

Closest peers in Healthcare, ranked by industry match, size, and score similarity. Cross-listings of BCYC are excluded.

TickerCompanyMkt CapStockRankSignal
BCYCBicycle Therapeutics plc(you)$248M15Strong Sell
AVCT.LAvacta Group Plc$371M10Strong Sell
AUTLAutolus Therapeutics plc$410M11Strong Sell
SCLP.LScancell Holdings plc$165M2Strong Sell
TLSATiziana Life Sciences Ltd$121M5Strong Sell
OXB.LOxford Biomedica plc$833M13Strong Sell
4BB.L4basebio PLC$110M5Strong Sell
OKYOOKYO Pharma Limited$73M8Strong Sell
MREOMereo BioPharma Group plc$54M18Strong Sell
HEMO.LHemogenyx Pharmaceuticals Plc$64M7Strong Sell

Peer medians: ROE -4.5% · P/E 24.1x · Gross margin 54.5%

Company Deep Dive

Business segments breakdown, earnings transcript analysis, management credibility scoring, competitive landscape, and scenario modelling.

Request Deep Dive(50 Feathers)

Bicycle Therapeutics plc (BCYC): Stock Score Summary

Bicycle Therapeutics plc (BCYC) has a MoatMap StockRank of 15/100 based on Quality (24/100), Value (38/100), and Momentum (31/100) factor scores. The current signal is STRONG SELL.

Bicycle Therapeutics plc is a clinical-stage biopharmaceutical company pioneering a novel class of medicines called Bicycles®, which are synthetic short peptides with unique therapeutic properties. The company leverages its proprietary Bicycle® platform to develop highly selective and potent small-molecule-like biologics for oncology and other therapeutic areas. This innovative drug modality aims to address difficult-to-drug targets and improve patient outcomes.

Key Financial Metrics

Price$3.65
Market Cap$248M
P/E (Forward)-1.60
Price/Book0.49
Return on Equity-32.3%
Return on Invested Capital-28.5%
Debt/Equity0.03x
Operating Margin-8673.9%
Revenue Growth-78.5%
Free Cash Flow$-208M

Bicycle Therapeutics plc operates in the Biotechnology industry, part of the Healthcare sector (United Kingdom).

Frequently Asked Questions

What is Bicycle Therapeutics plc’s (BCYC) StockRank?
MoatMap’s StockRank for Bicycle Therapeutics plc (BCYC) is 15/100, with a Strong Sell signal. It is a composite of Quality (24), Value (38), and Momentum (31), each scored against its sector. The composite is then ranked across MoatMap’s universe of 24,000+ stocks.
Does Bicycle Therapeutics plc have an economic moat?
Bicycle Therapeutics plc (BCYC) has a Quality factor score of 24/100. The Quality factor combines ROIC, Piotroski F-Score, and leverage: the financial fingerprints of a durable competitive advantage. A Quality score above 70 typically indicates a company with the characteristics of a moated business.
Is Bicycle Therapeutics plc a buy, hold, or sell?
MoatMap’s current signal for Bicycle Therapeutics plc (BCYC) is Strong Sell, based on a StockRank of 15/100. Signals are derived mechanically from the StockRank composite and should be one input among many; combine with your own thesis on management, competitive position, and valuation.
What sector is Bicycle Therapeutics plc in?
Bicycle Therapeutics plc (BCYC) operates in the Healthcare sector, specifically the Biotechnology industry (United Kingdom).