TLSA

Strong SellSinker

Tiziana Life Sciences Ltd · Healthcare · United Kingdom · $121M cap · $583K/day traded

$0.8823 -7.1% · close 26 Oct · scored 27 Oct

Sinker: Weak, expensive and falling. Nothing here to keep it afloat.

5
StockRank
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Quality
12
Value
25
Momentum
36

As of 27 Oct 2026, MoatMap's StockRank for Tiziana Life Sciences Ltd (TLSA) is 5/100, ranked against 24,000+ stocks in 35 markets (Quality 12, Value 25, Momentum 36, each scored against its sector).

Does StockRank work? Each month we publish how every decile did, whichever way it went. See the record →

P/E (TTM)
—
peers 24.1x
ROE
-780.6%
peers -4.5%
D/E
8.8x
peers 0.2x
Dividend %
—
trailing yield

ABOUT TIZIANA LIFE SCIENCES LTD

Read

Tiziana Life Sciences Ltd is a clinical-stage biotechnology company focused on developing novel therapeutics for oncology, inflammatory diseases, and neurodegenerative disorders. The company's competitive moat is based on its innovative pipeline, particularly its orally administered antibody platform designed for improved drug delivery and efficacy. Tiziana operates as a niche biotech player, emphasizing novel mechanisms of action to address significant unmet medical needs.

FINANCIAL SUMMARY (USD)

Year2022202320242025CAGRTTM2026E2027EFwd CAGR
Revenue0000—————
EPS-0.15-0.17-0.11-0.16—-0.21-0.13-0.14—
Shares100.6M101.5M111.5M120.5M+19.8%127.3M———
Debt0.4M0.2M0.1M0.5M7.7%0.9M———
Equity19.6M5.5M3.9M52.0K-86.1%————
Op CF-19.6M-15.7M-1.5M-12.8M—-13.4M———
Inv CF-4.0M-1.3M-71.0K3.0M—————
Fin CF-55.0K40.0K4.5M10.0M—————
Loading 1Y...
PRICE (1Y) · USD+3.8%
0.80.91.01.11.215 Sep6 Oct26 Oct
SMA 50SMA 200

Price checkFinding a floorExperimental

No new 52-week low for 5 weeks, 16% above that low, but not back above a rising 50-day average.

SwingsVery bumpy

Swung more than 89% of stocks we rank over the past year (81% a year).

How this is worked out

StockRank judges the business. The price check reads only the chart: it is the price side of the Momentum score, in words.

The rules: Still falling is a new 52-week low in the last two weeks, at least 25% below the high. Finding a floor is no new low since. Turning up is 20 or more trading days without a new low, at least 10% off it, and back above a rising 50-day average. In an uptrend is above the 200-day average and within 15% of the high.

In 2,112 US drawdowns since 2001, buying while the price was still falling was followed by a further 20% drop 42% of the time. Waiting for a turn like this one cut that to 33%, at about 7% higher prices and with no better returns. Part of that cut is simply not buying: 13% of falls never turned, and waiting kept those out. Among turns that were bought, 38% still fell another 20%, and 33% of turns were followed by a new low within six months. The benefit was largest in crashes such as 2008 and 2020.

What it measures: day-to-day price moves over the past year, as a yearly figure, ranked against every stock we cover. Very calm under 20% a year, Calm 20 to 30%, Average 30 to 40%, Bumpy 40 to 55%, Very bumpy above that.

What we found: across about 13,500 stocks in 34 markets (2002 to 2025), past swings were a good guide to the next year's, and bumpier stocks fell further. How much further changed too much between eras to put a number on it.

Calm is not safe: a calm stock can still slide steadily.

Rules fixed before any data was fetched. Describes the chart, not a recommendation.

Close
$0.8823
RSI (14)
22.1
52-Week Range-58.0% from high
Low $0.76High $2.10

SCORE BREAKDOWN

Quality
12
ROIC
-6438.1%0.0
ROE
-780.6%25.0
GP/Assets
—N/A
Op. Margin
0.0%38.6
FCF/Assets
-111.9%2.1
Piotroski
12.3
Int. Cover
-50.0x5.8
D/E Ratio
8.77x1.1
Current Ratio
0.69x4.6
Value
25
P/E (TTM)
—N/A
EV/EBITDA
-5.1x25.0
P/FCF
—N/A
P/B
-45.2x25.0
P/S
—N/A
Div Yield
—N/A
Momentum
36
52W High %
42%19.0
RS 6M
-37%19.9
SMA 50/200
0.84x19.9
EPS Rev 4W
+8.8%96.2
EPS Rev 12W
+8.8%83.0
EPS Improve
+13%29.7
Q Growth
—N/A

FUNDAMENTALS

Market Cap
$121M
P/E (Forward)
-5.2x
Gross Margin
—

SECTOR PEERS

Closest peers in Healthcare, ranked by industry match, size, and score similarity. Cross-listings of TLSA are excluded.

TickerCompanyMkt CapStockRankSignal
TLSATiziana Life Sciences Ltd(you)$121M5Strong Sell
4BB.L4basebio PLC$110M5Strong Sell
SCLP.LScancell Holdings plc$165M2Strong Sell
OKYOOKYO Pharma Limited$73M8Strong Sell
HEMO.LHemogenyx Pharmaceuticals Plc$64M7Strong Sell
SAR.LSareum Holdings plc$51M10Strong Sell
BCYCBicycle Therapeutics plc$248M15Strong Sell
COIL.LCoiled Therapeutics plc$41M8Strong Sell
AVCT.LAvacta Group Plc$371M10Strong Sell
IMM.LImmuPharma plc$32M4Strong Sell

Peer medians: ROE -4.5% · P/E 24.1x · Gross margin 54.5%

Company Deep Dive

Business segments breakdown, earnings transcript analysis, management credibility scoring, competitive landscape, and scenario modelling.

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Tiziana Life Sciences Ltd (TLSA): Stock Score Summary

Tiziana Life Sciences Ltd (TLSA) has a MoatMap StockRank of 5/100 based on Quality (12/100), Value (25/100), and Momentum (36/100) factor scores. The current signal is STRONG SELL.

Tiziana Life Sciences Ltd is a clinical-stage biotechnology company focused on developing novel therapeutics for oncology, inflammatory diseases, and neurodegenerative disorders. The company's competitive moat is based on its innovative pipeline, particularly its orally administered antibody platform designed for improved drug delivery and efficacy. Tiziana operates as a niche biotech player, emphasizing novel mechanisms of action to address significant unmet medical needs.

Key Financial Metrics

Price$0.8823
Market Cap$121M
P/E (Forward)-5.22
Price/Book-45.24
Return on Equity-780.6%
Return on Invested Capital-6438.1%
Debt/Equity8.77x
Operating Margin0.0%
Free Cash Flow$-13M

Tiziana Life Sciences Ltd operates in the Biotechnology industry, part of the Healthcare sector (United Kingdom).

Frequently Asked Questions

What is Tiziana Life Sciences Ltd’s (TLSA) StockRank?
MoatMap’s StockRank for Tiziana Life Sciences Ltd (TLSA) is 5/100, with a Strong Sell signal. It is a composite of Quality (12), Value (25), and Momentum (36), each scored against its sector. The composite is then ranked across MoatMap’s universe of 24,000+ stocks.
Does Tiziana Life Sciences Ltd have an economic moat?
Tiziana Life Sciences Ltd (TLSA) has a Quality factor score of 12/100. The Quality factor combines ROIC, Piotroski F-Score, and leverage: the financial fingerprints of a durable competitive advantage. A Quality score above 70 typically indicates a company with the characteristics of a moated business.
Is Tiziana Life Sciences Ltd a buy, hold, or sell?
MoatMap’s current signal for Tiziana Life Sciences Ltd (TLSA) is Strong Sell, based on a StockRank of 5/100. Signals are derived mechanically from the StockRank composite and should be one input among many; combine with your own thesis on management, competitive position, and valuation.
What sector is Tiziana Life Sciences Ltd in?
Tiziana Life Sciences Ltd (TLSA) operates in the Healthcare sector, specifically the Biotechnology industry (United Kingdom).