ENGN

Sinker

enGene Therapeutics Inc. · Healthcare · Canada · $105M cap · $2.9M/day traded

$2.28 +26.7% · close 12 Nov · scored 13 Nov

Score up 1.1 since 12 Nov.

Sinker: Weak business, rich price and weak momentum. Nothing here to keep it afloat.

13
Score
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Quality
25
Value
35
Momentum
30

As of 13 Nov 2026, the MoatMap Score for enGene Therapeutics Inc. (ENGN) is 13/100, ranked against 25,000+ stocks in 38 markets (Quality 25, Value 35, Momentum 30, each scored against its sector).

Does the score work? Each tenth of the ranking, tracked monthly. See the record →

P/E (TTM)
—
peers 19.0x
ROE
-60.5%
peers -27.0%
D/E
0.1x
peers 0.1x
Dividend %
—
trailing yield

ABOUT ENGENE THERAPEUTICS INC.

Read

enGene Therapeutics Inc. is a clinical-stage biotechnology company developing a novel gene therapy platform for the localized delivery of therapeutics, particularly in oncology and immunology. The company's proprietary non-viral DDX platform is designed for sustained, targeted protein expression directly at the disease site, potentially offering improved safety and efficacy. It positions itself as an innovator in gene therapy, initially focusing on addressing high unmet needs in bladder cancer treatment.

FINANCIAL SUMMARY (USD)

Year2022202320242025CAGRTTM2026E2027EFwd CAGR
Revenue0000———5.6M—
EPS-0.43-1.56-1.46-2.29—-2.07-1.81-1.51—
Shares67.0M67.0M51.0M52.0M-22.4%67.0M———
Debt32.1M9.8M25.0M31.8M-0.3%33.3M———
Equity-23.5M72.5M272.6M167.7M52.1%————
Op CF-17.6M-24.7M-48.3M-99.2M—-103.3M———
Inv CF-0.2M-0.3M-126.0M-25.1M—————
Fin CF28.0M86.1M265.7M1.5M—————
PRICE (1Y) · USD+17.5%
1.51.71.92.12.32 Oct23 Oct12 Nov
SMA 50SMA 200

Price checkFinding a floorExperimental

No new 52-week low for 25 weeks, 63% above that low, but not back above a rising 50-day average.

SwingsVery bumpy

Swung more than 97% of stocks we rank over the past year (volatility 112% a year).

How this is worked out

The Price check reads only the chart, the price side of the Momentum score in words; it is not the MoatMap Score.

  • Still falling: It set a new 52-week low in the last two weeks, after a deep fall.
  • Finding a floor (this stock): It fell hard, but has set no new low for more than two weeks.
  • Turning up: It has climbed off its low and is back above a rising 50-day average.
  • In an uptrend: It is near its 52-week high and above its 200-day average.
  • No clear trend: None of the above: no recent deep fall and no steady climb.
  • No read yet: Not enough price history yet: it needs a year of trading.

In past US falls, waiting for Turning up cut the chance of another 20% drop from 42% to 33%. Returns were no better, and 33% of turns failed.

The exact rules

Still falling is a new 52-week low in the last two weeks, at least 25% below the high, with the low set after the high. Finding a floor is the same fall with no new low in the last two weeks. Turning up is 20 or more trading days without a new low, at least 10% off it, and back above a rising 50-day average. In an uptrend is above the 200-day average, with the 50-day average above the 200-day, and within 15% of the high. No clear trend is everything else. No read yet is under 252 trading days of history, or missing data. A new state shows once it has held for three trading days.

In 2,112 US drawdowns since 2001, buying while the price was still falling was followed by a further 20% drop 42% of the time. Waiting for a turn (the Turning up rule above) cut that to 33%, at about 7% higher prices and with no better returns. Part of that cut is simply not buying: 13% of falls never turned, and waiting kept those out. Among turns that were bought, 38% still fell another 20%, and 33% of turns were followed by a new low within six months. The benefit was largest in crashes such as 2008 and 2020.

What it measures: how much the price moved day to day over the past year, scaled to a yearly figure (annualised volatility) and ranked against every stock we cover. Very calm under 20% a year, Calm 20 to 30%, Average 30 to 40%, Bumpy 40 to 55%, Very bumpy above that.

What we found: across about 13,500 stocks in 34 markets (2002 to 2025), past swings were a good guide to the next year's, and bumpier stocks fell further. How much further changed too much between eras to put a number on it.

Calm is not safe: a calm stock can still slide steadily.

Rules fixed before any data was fetched. Describes the chart, not a recommendation.

Close
$2.28
RSI (14)
77.3
52-Week Range-81.4% from high
Low $1.40High $12.25

SCORE BREAKDOWN

Quality
25
ROIC
-67.4%11.1
ROE
-60.5%15.2
GP/Assets
—N/A
Op. Margin
0.0%36.8
FCF/Assets
-45.5%9.1
Piotroski
29.3
Int. Cover
-41.6x12.9
D/E Ratio
0.14x56.3
Current Ratio
10.21x87.8
Value
35
P/E (TTM)
—N/A
EV/EBITDA
0.9x25.0
P/FCF
—N/A
P/B
0.5x94.3
P/S
—N/A
Div Yield
—N/A
Momentum
30
52W High %
19%4.4
RS 6M
24%81.5
SMA 50/200
0.45x2.0
EPS Rev 4W
-3.9%8.9
EPS Rev 12W
-7.5%13.4
EPS Improve
+27%41.2
Q Growth
—N/A

FUNDAMENTALS

Market Cap
$105M
P/E (Forward)
-1.2x
Gross Margin
—

SECTOR PEERS

Closest peers in Healthcare, ranked by industry match, size, and score similarity. Cross-listings of ENGN are excluded.

TickerCompanyMkt CapScore
ENGNenGene Therapeutics Inc.(you)$105M13
MSCL.TOSatellos Bioscience Inc.$138M12
BETR.CNBetterLife Pharma Inc.$99M23
OBI.LOndine Biomedical Inc.$73M5
PMNProMIS Neurosciences, Inc.$75M3
NGENNervGen Pharma Corp.$154M4
MISTMilestone Pharmaceuticals Inc.$81M1
EDSAEdesa Biotech, Inc.$51M2
ARCH.VArch Biopartners Inc.$42M21
BCT.TOBriaCell Therapeutics Corp.$30M11

Peer medians: ROE -27.0% · P/E 19.0x · Gross margin 51.7%

Company Deep Dive

A 10,000-word report: the business and its segments, what management promised on earnings calls and whether it delivered, the competition, and how things could turn out.

Request Deep Dive(50 Feathers)

enGene Therapeutics Inc. (ENGN): Stock Score Summary

enGene Therapeutics Inc. (ENGN) has a MoatMap Score of 13/100 based on Quality (25/100), Value (35/100), and Momentum (30/100) factor scores.

enGene Therapeutics Inc. is a clinical-stage biotechnology company developing a novel gene therapy platform for the localized delivery of therapeutics, particularly in oncology and immunology. The company's proprietary non-viral DDX platform is designed for sustained, targeted protein expression directly at the disease site, potentially offering improved safety and efficacy. It positions itself as an innovator in gene therapy, initially focusing on addressing high unmet needs in bladder cancer treatment.

Director dealings

From 2 Jan 2026 to 12 Nov 2026, MoatMap's records hold no sales and 1 purchase of enGene Therapeutics Inc. (ENGN) shares by its directors. The largest: Grossman William bought 5,102 shares at $1.97 on 22 Sep 2026 (about $10K).

ENGN insider filings, last 180 days

Key Financial Metrics

Price$2.28
Market Cap$105M
P/E (Forward)-1.16
Price/Book0.51
Return on Equity-60.5%
Return on Invested Capital-67.4%
Debt/Equity0.14x
Operating Margin0.0%
Free Cash Flow$-101M

enGene Therapeutics Inc. operates in the Biotechnology industry, part of the Healthcare sector (Canada).

Frequently Asked Questions

What is enGene Therapeutics Inc.’s (ENGN) MoatMap Score?
The MoatMap Score for enGene Therapeutics Inc. (ENGN) is 13/100. It is a composite of Quality (25), Value (35), and Momentum (30), each scored against its sector. The composite is then ranked across MoatMap’s universe of 25,000+ stocks.
Does enGene Therapeutics Inc. have an economic moat?
enGene Therapeutics Inc. (ENGN) has a Quality factor score of 25/100. Quality blends several measures of profitability and financial strength, led by gross profit to assets, return on invested capital and free cash flow to assets. A high score describes the financial record a durable advantage tends to leave; it does not prove a moat.
What sector is enGene Therapeutics Inc. in?
enGene Therapeutics Inc. (ENGN) operates in the Healthcare sector, specifically the Biotechnology industry (Canada).