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KPTI

SELL

Karyopharm Therapeutics Inc. · Healthcare · United States · $168M · Avg Vol: $4M/d

24
StockRank
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Q
24
V
31
M
57
P/E (TTM)
ROE
D/E
Dividend %

COMPANY DESCRIPTION

Karyopharm Therapeutics Inc. is a commercial-stage pharmaceutical company dedicated to developing and commercializing novel cancer therapies, primarily focusing on its proprietary nuclear export inhibitors, with XPOVIO as its lead approved product. The company's competitive moat lies in its unique drug class and intellectual property in nuclear export modulation, addressing significant unmet needs in oncology. Karyopharm operates as an innovative biotech, expanding the indications for its approved drug and advancing its pipeline.

FINANCIAL SUMMARY (USD)

Year2022202320242025CAGRTTM2026E2027EFwd CAGR
Revenue157.1M146.0M145.2M146.1M-2.4%151.1M138.2M149.0M1.0%
EPS-10.09-6.35-3.51-17.93-12.91
Shares22.7M22.7M22.7M18.3M-19.2%22.7M
Debt179.1M177.0M194.5M233.6M9.3%303.2M
Equity-16.7M-136.2M-186.0M-292.9M
Op CF-149.6M-92.7M-127.5M-75.4M-59.1M
Inv CF-104.3M7.9M95.5M43.4M
Fin CF193.7M1.1M41.6M30.0M
Loading 1Y...
PRICE (1Y)-17.7%
7.097.998.889.7810.67Jun 11Jul 6Jul 24
SMA 50SMA 200
Close
$7.41
RSI (14)
32.4
52W High
$10.99
From 52W High
0.7%

SCORE BREAKDOWN

Quality
24
ROIC
-902.1%0.3
ROE
N/A
GP/Assets
18.8%45.1
Op. Margin
-76.3%19.1
FCF/Assets
-22.4%16.4
Piotroski
430.1
Int. Cover
-3.1x30.9
D/E Ratio
N/A
Current Ratio
1.08x13.1
Value
31
P/E (TTM)
N/A
EV/EBITDA
-4.5x25.0
P/FCF
N/A
P/B
-0.6x25.0
P/S
1.1x81.3
Div Yield
N/A
Momentum
57
52W High %
67%49.8
RS 6M
4%77.5
SMA 50/200
1.18x88.2
EPS Rev 4W
0.0%62.5
EPS Rev 12W
-12.0%12.0
EPS Improve
+62%60.8
Q Growth
N/A

FUNDAMENTALS

Market Cap
$168M
P/E (Forward)
-1.5x
Gross Margin
13.5%

SECTOR PEERS

Closest peers in Healthcare, ranked by industry match, size, and score similarity. Cross-listings of KPTI are excluded.

TickerCompanyMkt CapStockRankSignal
KPTIKaryopharm Therapeutics Inc.(you)$168M24SELL
ACOGAlpha Cognition Inc. Common Stock$172M26SELL
EQEquillium, Inc.$157M23SELL
NRXPNRx Pharmaceuticals, Inc.$161M27SELL
NKTXNkarta, Inc.$162M29SELL
MGNXMacroGenics, Inc.$235M25SELL
OBIOOrchestra BioMed Holdings, Inc.$224M21SELL
HURATuHURA Biosciences, Inc.$134M20SELL
CRBPCorbus Pharmaceuticals Holdings, Inc.$170M15STRONG SELL
WHWKWhitehawk Therapeutics, Inc.$183M31SELL

Peer medians: ROE -25.5% · P/E 27.7x · Gross margin 50.7%

Karyopharm Therapeutics Inc. (KPTI) — Stock Score Summary

Karyopharm Therapeutics Inc. (KPTI) has a MoatMap StockRank of 24/100 based on Quality (24/100), Value (31/100), and Momentum (57/100) factor scores. The current signal is SELL.

Karyopharm Therapeutics Inc. is a commercial-stage pharmaceutical company dedicated to developing and commercializing novel cancer therapies, primarily focusing on its proprietary nuclear export inhibitors, with XPOVIO as its lead approved product. The company's competitive moat lies in its unique drug class and intellectual property in nuclear export modulation, addressing significant unmet needs in oncology. Karyopharm operates as an innovative biotech, expanding the indications for its approved drug and advancing its pipeline.

Key Financial Metrics

Price$7.41
Market Cap$168M
P/E (Forward)-1.53
Price/Book-0.63
Return on Invested Capital-902.1%
Gross Margin13.5%
Operating Margin-76.3%
Revenue Growth16.8%
Free Cash Flow$-24M

Karyopharm Therapeutics Inc. operates in the Biotechnology industry, part of the Healthcare sector (United States).

Frequently Asked Questions

What is Karyopharm Therapeutics Inc.’s (KPTI) StockRank?
MoatMap’s StockRank for Karyopharm Therapeutics Inc. (KPTI) is 24/100, with a Sell signal. It is a composite of Quality (24), Value (31), and Momentum (57) factor ranks across MoatMap’s 20,000+ stock universe.
Does Karyopharm Therapeutics Inc. have an economic moat?
Karyopharm Therapeutics Inc. (KPTI) has a Quality factor score of 24/100. The Quality factor combines ROIC, Piotroski F-Score, and leverage — the financial fingerprints of a durable competitive advantage. A Quality score above 70 typically indicates a company with the characteristics of a moated business.
Is Karyopharm Therapeutics Inc. a buy, hold, or sell?
MoatMap’s current signal for Karyopharm Therapeutics Inc. (KPTI) is Sell, based on a StockRank of 24/100. Signals are derived mechanically from the StockRank composite and should be one input among many — combine with your own thesis on management, competitive position, and valuation.
What sector is Karyopharm Therapeutics Inc. in?
Karyopharm Therapeutics Inc. (KPTI) operates in the Healthcare sector, specifically the Biotechnology industry (United States).