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SION

SELL

Sionna Therapeutics, Inc. · Healthcare · United States · $2.1B · Avg Vol: $25M/d

28
StockRank
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Q
38
V
24
M
55
P/E (TTM)
ROE
-26.7%
D/E
0.0x
Dividend %

COMPANY DESCRIPTION

Sionna Therapeutics, Inc. is a clinical-stage biotechnology company dedicated to developing novel small molecule therapeutics for cystic fibrosis (CF), aiming to restore function to the critical CFTR protein. Its competitive moat lies in an innovative scientific approach that targets distinct mechanisms to restore CFTR function, potentially offering superior benefits or reaching patient populations underserved by current therapies. Sionna is focused on delivering best-in-class or first-in-class treatments for this specific genetic disorder.

FINANCIAL SUMMARY (USD)

Year2022202320242025CAGRTTM2026E2027EFwd CAGR
Revenue00003.0M
EPS-2.32-1.70-1.45-1.88-1.72-2.54-2.80
Shares42.4M42.4M42.4M44.7M+5.4%45.2M
Debt010.5M9.7M8.7M-9.0%8.4M
Equity-69.9M-114.9M-163.7M306.8M
Op CF-36.1M-43.7M-52.8M-66.3M-71.8M
Inv CF-29.3M27.4M-126.9M-118.7M
Fin CF110.9M31.0K179.0M205.7M
Loading 1Y...
PRICE (1Y)+26.3%
34.7538.4142.0845.7449.41Jun 12Jul 7Jul 27
SMA 50SMA 200
Close
$45.38
RSI (14)
51.0
52W High
$51.56
From 52W High
0.9%

SCORE BREAKDOWN

Quality
38
ROIC
-28.3%25.5
ROE
-26.7%28.4
GP/Assets
N/A
Op. Margin
0.0%41.3
FCF/Assets
-14.0%24.9
Piotroski
439.0
Int. Cover
N/A
D/E Ratio
0.03x76.0
Current Ratio
22.60x96.5
Value
24
P/E (TTM)
N/A
EV/EBITDA
-18.9x25.0
P/FCF
N/A
P/B
7.1x17.7
P/S
N/A
Div Yield
N/A
Momentum
55
52W High %
88%83.2
RS 6M
-1%72.4
SMA 50/200
1.04x73.6
EPS Rev 4W
0.0%62.6
EPS Rev 12W
-8.6%14.7
EPS Improve
-63%8.0
Q Growth
N/A

FUNDAMENTALS

Market Cap
$2.1B
P/E (Forward)
-16.3x
Gross Margin
0.0%

SECTOR PEERS

Closest peers in Healthcare, ranked by industry match, size, and score similarity. Cross-listings of SION are excluded.

TickerCompanyMkt CapStockRankSignal
SIONSionna Therapeutics, Inc.(you)$2.1B28SELL
NUVBNuvation Bio Inc.$2.2B28SELL
PVLAPalvella Therapeutics, Inc.$2.0B30SELL
STOKStoke Therapeutics, Inc.$1.8B27SELL
GLUEMonte Rosa Therapeutics, Inc.$1.9B24SELL
TARSTarsus Pharmaceuticals, Inc.$2.6B28SELL
NRIXNurix Therapeutics, Inc.$2.4B30SELL
KODKodiak Sciences Inc.$2.6B27SELL
RAPPRapport Therapeutics, Inc.$1.9B33SELL
AGIOAgios Pharmaceuticals, Inc.$2.2B34SELL

Peer medians: ROE -25.5% · P/E 27.6x · Gross margin 50.6%

Sionna Therapeutics, Inc. (SION) — Stock Score Summary

Sionna Therapeutics, Inc. (SION) has a MoatMap StockRank of 28/100 based on Quality (38/100), Value (24/100), and Momentum (55/100) factor scores. The current signal is SELL.

Sionna Therapeutics, Inc. is a clinical-stage biotechnology company dedicated to developing novel small molecule therapeutics for cystic fibrosis (CF), aiming to restore function to the critical CFTR protein. Its competitive moat lies in an innovative scientific approach that targets distinct mechanisms to restore CFTR function, potentially offering superior benefits or reaching patient populations underserved by current therapies. Sionna is focused on delivering best-in-class or first-in-class treatments for this specific genetic disorder.

Key Financial Metrics

Price$45.38
Market Cap$2.1B
P/E (Forward)-16.30
Price/Book7.15
Return on Equity-26.7%
Return on Invested Capital-28.3%
Debt/Equity0.03x
Gross Margin0.0%
Operating Margin0.0%
Free Cash Flow$-46M

Sionna Therapeutics, Inc. operates in the Biotechnology industry, part of the Healthcare sector (United States).

Frequently Asked Questions

What is Sionna Therapeutics, Inc.’s (SION) StockRank?
MoatMap’s StockRank for Sionna Therapeutics, Inc. (SION) is 28/100, with a Sell signal. It is a composite of Quality (38), Value (24), and Momentum (55) factor ranks across MoatMap’s 20,000+ stock universe.
Does Sionna Therapeutics, Inc. have an economic moat?
Sionna Therapeutics, Inc. (SION) has a Quality factor score of 38/100. The Quality factor combines ROIC, Piotroski F-Score, and leverage — the financial fingerprints of a durable competitive advantage. A Quality score above 70 typically indicates a company with the characteristics of a moated business.
Is Sionna Therapeutics, Inc. a buy, hold, or sell?
MoatMap’s current signal for Sionna Therapeutics, Inc. (SION) is Sell, based on a StockRank of 28/100. Signals are derived mechanically from the StockRank composite and should be one input among many — combine with your own thesis on management, competitive position, and valuation.
What sector is Sionna Therapeutics, Inc. in?
Sionna Therapeutics, Inc. (SION) operates in the Healthcare sector, specifically the Biotechnology industry (United States).