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KRYS

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Krystal Biotech, Inc. · Healthcare · United States · $10.4B · Avg Vol: $96M/d

74
StockRank
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Q
85
V
21
M
62
P/E (TTM)
44.8x
ROE
20.1%
D/E
0.0x
Dividend %
AI CONVICTION THESIS

Krystal Biotech has strong quality Q83 and momentum M76, but value at V16 is among the lowest scores in this run and far below the calibrated floor, so stage one fails. Insider selling is separately adverse.

COMPANY DESCRIPTION

Krystal Biotech, Inc. is a biotechnology company developing and commercializing gene therapies for patients with rare diseases, with an initial focus on serious dermatological conditions. Its proprietary "STAR-D" gene therapy platform provides a competitive moat by enabling repeat administration of gene therapies, distinguishing its approach in the rapidly evolving genetic medicine landscape. Krystal is a niche player with a lead product, Vyjuvek, now commercialized for Dystrophic Epidermolysis Bullosa (DEB).

FINANCIAL SUMMARY (USD)

Year2022202320242025CAGRTTM2026E2027EFwd CAGR
Revenue050.7M290.5M389.1M177.0%440.5M512.6M654.5M29.7%
EPS-5.490.403.127.08320.7%7.998.149.7317.2%
Shares25.8M28.2M28.8M29.2M+13.3%29.6M
Debt8.9M8.1M7.3M9.3M1.5%8.9M
Equity522.2M778.6M946.4M1.2B32.7%
Op CF-100.6M-88.8M123.4M200.9M62.7%272.3M
Inv CF-114.1M82.6M-163.4M-58.4M
Fin CF35.3M202.8M27.0M8.7M
Loading 1Y...
PRICE (1Y)-4.2%
313327342357371Jul 29Aug 19Sep 9
SMA 50SMA 200

Close
$348.09
RSI (14)
52.6
52W High
$382.54
From 52W High
0.9%

SCORE BREAKDOWN

Quality
85
ROIC
16.1%85.4
ROE
20.1%88.4
GP/Assets
31.3%65.9
Op. Margin
49.0%98.0
FCF/Assets
19.3%96.2
Piotroski
783.9
Int. Cover
50.0x89.2
D/E Ratio
0.01x87.3
Current Ratio
8.32x84.3
Value
21
P/E (TTM)
44.8x24.8
EV/EBITDA
51.0x11.3
P/FCF
40.4x35.2
P/B
7.8x16.2
P/S
24.1x14.3
Div Yield
N/A
Momentum
62
52W High %
91%86.9
RS 6M
20%81.2
SMA 50/200
1.20x87.6
EPS Rev 4W
-4.3%14.5
EPS Rev 12W
-6.8%15.6
EPS Improve
+18%32.5
Q Growth
43%71.6

FUNDAMENTALS

Market Cap
$10.4B
P/E (Forward)
38.1x
Gross Margin
94.6%

SECTOR PEERS

Closest peers in Healthcare, ranked by industry match, size, and score similarity. Cross-listings of KRYS are excluded.

TickerCompanyMkt CapStockRankSignal
KRYSKrystal Biotech, Inc.(you)$10.4B74Buy
TECHBio-Techne Corporation$11.3B76Buy
CORTCorcept Therapeutics Incorporated$12.3B71Buy
BMRNBioMarin Pharmaceutical Inc.$12.5B63Hold
LGNDLigand Pharmaceuticals Incorporated$5.6B67Buy
CAICaris Life Sciences, Inc.$7.2B60Hold
TGTXTG Therapeutics, Inc.$8.3B57Hold
ACADACADIA Pharmaceuticals Inc.$5.0B83Strong Buy
HALOHalozyme Therapeutics, Inc.$12.0B95Strong Buy
TVTXTravere Therapeutics, Inc.$6.2B54Hold

Peer medians: ROE -30.8% · P/E 26.9x · Gross margin 58.1%

Krystal Biotech, Inc. (KRYS): Stock Score Summary

Krystal Biotech, Inc. (KRYS) has a MoatMap StockRank of 74/100 based on Quality (85/100), Value (21/100), and Momentum (62/100) factor scores. The current signal is BUY. Krystal Biotech has strong quality Q83 and momentum M76, but value at V16 is among the lowest scores in this run and far below the calibrated floor, so stage one fails. Insider selling is separately adverse.

Krystal Biotech, Inc. is a biotechnology company developing and commercializing gene therapies for patients with rare diseases, with an initial focus on serious dermatological conditions. Its proprietary "STAR-D" gene therapy platform provides a competitive moat by enabling repeat administration of gene therapies, distinguishing its approach in the rapidly evolving genetic medicine landscape. Krystal is a niche player with a lead product, Vyjuvek, now commercialized for Dystrophic Epidermolysis Bullosa (DEB).

Key Financial Metrics

Price$348.09
Market Cap$10.4B
P/E (TTM)44.84
P/E (Forward)38.12
Price/Book7.80
Return on Equity20.1%
Return on Invested Capital16.1%
Debt/Equity0.01x
Gross Margin94.6%
Operating Margin49.0%
Revenue Growth24.1%
Free Cash Flow$258M

Krystal Biotech, Inc. operates in the Biotechnology industry, part of the Healthcare sector (United States).

Frequently Asked Questions

What is Krystal Biotech, Inc.’s (KRYS) StockRank?
MoatMap’s StockRank for Krystal Biotech, Inc. (KRYS) is 74/100, with a Buy signal. It is a composite of Quality (85), Value (21), and Momentum (62) factor ranks across MoatMap’s universe of 25,000+ stocks.
Does Krystal Biotech, Inc. have an economic moat?
Krystal Biotech, Inc. (KRYS) has a Quality factor score of 85/100. The Quality factor combines ROIC, Piotroski F-Score, and leverage: the financial fingerprints of a durable competitive advantage. A Quality score above 70 typically indicates a company with the characteristics of a moated business.
Is Krystal Biotech, Inc. a buy, hold, or sell?
MoatMap’s current signal for Krystal Biotech, Inc. (KRYS) is Buy, based on a StockRank of 74/100. Signals are derived mechanically from the StockRank composite and should be one input among many; combine with your own thesis on management, competitive position, and valuation.
What sector is Krystal Biotech, Inc. in?
Krystal Biotech, Inc. (KRYS) operates in the Healthcare sector, specifically the Biotechnology industry (United States).