LGND

BuyPremium GrowerAI neutral

Ligand Pharmaceuticals Incorporated · Healthcare · United States · $6.1B cap · $78.2M/day traded

$303.53 -1.4% · close 23 Oct · scored 24 Oct

Premium Grower: Strong business with the market behind it, priced at a premium.

71
StockRank
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Report expected 5 Nov: the next-year EPS estimate has risen 3.1% over the last 14 weeks.

Quality
64
Value
23
Momentum
79

As of 24 Oct 2026, MoatMap's StockRank for Ligand Pharmaceuticals Incorporated (LGND) is 71/100, ranked against 24,000+ stocks in 35 markets (Quality 64, Value 23, Momentum 79, each scored against its sector).

Does StockRank work? Each month we publish how every decile did, whichever way it went. See the record →

P/E (TTM)
32.0x
peers 27.3x
ROE
22.0%
peers -31.5%
D/E
1.2x
peers 0.2x
Dividend %
—
trailing yield
AI CONVICTION THESIS

Ligand is a royalty aggregator that earns high-margin royalties on drugs developed by partners and keeps buying new royalty streams, such as its recent $23 million purchase tied to Santen's Ryjunea. It is an asset-light model with strong momentum. Much of that momentum appears reflected in the valuation, however, and the value of the portfolio depends on clinical and commercial outcomes that Ligand does not control. Insiders sold 0.28% of shares outstanding over 90 days.

ABOUT LIGAND PHARMACEUTICALS INCORPORATED

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Ligand Pharmaceuticals Incorporated operates a unique royalty-based business model, focusing on developing and licensing proprietary drug discovery and development platforms to pharmaceutical partners. Its primary competitive moat is built around its patented Captisol® technology, which significantly enhances drug solubility and stability, making it a crucial component in numerous approved and pipeline drug products. This intellectual property-centric approach generates revenue through royalties on partners' sales rather than costly direct drug development.

FINANCIAL SUMMARY (USD)

Year2022202320242025CAGRTTM2026E2027EFwd CAGR
Revenue196.2M131.3M167.1M268.1M11.0%290.5M288.9M381.7M19.3%
EPS-1.983.02-0.226.4446.0%9.497.409.4721.3%
Shares17.0M17.6M19.1M19.8M+16.7%19.9M———
Debt87.7M6.2M7.1M451.5M72.6%1.1B———
Equity597.5M700.9M830.4M1.0B19.4%————
Op CF137.8M49.6M97.0M49.4M-29.0%131.7M———
Inv CF163.6M-11.7M-143.7M-377.3M—————
Fin CF-276.0M-59.9M97.1M428.2M—————
Loading 1Y...
PRICE (1Y) · USD+8.2%
27528529530531514 Sep5 Oct23 Oct
SMA 50SMA 200

Price checkIn an uptrendExperimental

Above its 200-day average and 7% below its 52-week high.

SwingsAverage

Calmer than 59% of stocks we rank over the past year (37% a year).

How this is worked out

StockRank judges the business. The price check reads only the chart: it is the price side of the Momentum score, in words.

The rules: Still falling is a new 52-week low in the last two weeks, at least 25% below the high. Finding a floor is no new low since. Turning up is 20 or more trading days without a new low, at least 10% off it, and back above a rising 50-day average. In an uptrend is above the 200-day average and within 15% of the high.

In 2,112 US drawdowns since 2001, buying while the price was still falling was followed by a further 20% drop 42% of the time. Waiting for a turn like this one cut that to 33%, at about 7% higher prices and with no better returns. Part of that cut is simply not buying: 13% of falls never turned, and waiting kept those out. Among turns that were bought, 38% still fell another 20%, and 33% of turns were followed by a new low within six months. The benefit was largest in crashes such as 2008 and 2020.

What it measures: day-to-day price moves over the past year, as a yearly figure, ranked against every stock we cover. Very calm under 20% a year, Calm 20 to 30%, Average 30 to 40%, Bumpy 40 to 55%, Very bumpy above that.

What we found: across about 13,500 stocks in 34 markets (2002 to 2025), past swings were a good guide to the next year's, and bumpier stocks fell further. How much further changed too much between eras to put a number on it.

Calm is not safe: a calm stock can still slide steadily.

Rules fixed before any data was fetched. Describes the chart, not a recommendation.

Close
$303.53
RSI (14)
48.1
52-Week Range-7.1% from high
Low $175.89High $326.63

SCORE BREAKDOWN

Quality
64
ROIC
16.0%84.3
ROE
22.0%89.7
GP/Assets
15.1%34.8
Op. Margin
13.5%70.8
FCF/Assets
7.7%79.1
Piotroski
549.0
Int. Cover
39.4x77.1
D/E Ratio
1.17x11.8
Current Ratio
31.18x98.0
Value
23
P/E (TTM)
32.0x37.0
EV/EBITDA
43.8x12.7
P/FCF
50.5x26.1
P/B
6.2x20.0
P/S
20.8x14.4
Div Yield
—N/A
Momentum
79
52W High %
93%89.8
RS 6M
24%82.7
SMA 50/200
1.18x87.0
EPS Rev 4W
+0.1%71.0
EPS Rev 12W
+3.0%74.9
EPS Improve
+26%37.4
Q Growth
901%97.9

FUNDAMENTALS

Market Cap
$6.1B
P/E (Forward)
25.4x
Gross Margin
81.2%

SECTOR PEERS

Closest peers in Healthcare, ranked by industry match, size, and score similarity. Cross-listings of LGND are excluded.

TickerCompanyMkt CapStockRankSignal
LGNDLigand Pharmaceuticals Incorporated(you)$6.1B71Buy
CAICaris Life Sciences, Inc.$9.0B68Buy
CORTCorcept Therapeutics Incorporated$9.3B67Buy
KRYSKrystal Biotech, Inc.$9.2B67Buy
PTGXProtagonist Therapeutics, Inc.$9.0B66Buy
TECHBio-Techne Corporation$11.4B73Buy
ACADAcadia Pharmaceuticals Inc.$3.4B79Buy
ADMAADMA Biologics, Inc.$2.4B77Buy
BMRNBioMarin Pharmaceutical Inc.$10.8B57Hold
ARQTArcutis Biotherapeutics, Inc.$3.9B53Hold

Peer medians: ROE -31.5% · P/E 27.3x · Gross margin 62.6%

Company Deep Dive

Business segments breakdown, earnings transcript analysis, management credibility scoring, competitive landscape, and scenario modelling.

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Ligand Pharmaceuticals Incorporated (LGND): Stock Score Summary

Ligand Pharmaceuticals Incorporated (LGND) has a MoatMap StockRank of 71/100 based on Quality (64/100), Value (23/100), and Momentum (79/100) factor scores. The current signal is BUY. Ligand is a royalty aggregator that earns high-margin royalties on drugs developed by partners and keeps buying new royalty streams, such as its recent $23 million purchase tied to Santen's Ryjunea. It is an asset-light model with strong momentum. Much of that momentum appears reflected in the valuation, however, and the value of the portfolio depends on clinical and commercial outcomes that Ligand does not control. Insiders sold 0.28% of shares outstanding over 90 days.

Ligand Pharmaceuticals Incorporated operates a unique royalty-based business model, focusing on developing and licensing proprietary drug discovery and development platforms to pharmaceutical partners. Its primary competitive moat is built around its patented Captisol® technology, which significantly enhances drug solubility and stability, making it a crucial component in numerous approved and pipeline drug products. This intellectual property-centric approach generates revenue through royalties on partners' sales rather than costly direct drug development.

Key Financial Metrics

Price$303.53
Market Cap$6.1B
P/E (TTM)31.98
P/E (Forward)25.38
Price/Book6.25
Return on Equity22.0%
Return on Invested Capital16.0%
Debt/Equity1.17x
Gross Margin81.2%
Operating Margin13.5%
Revenue Growth33.7%
Free Cash Flow$120M

Ligand Pharmaceuticals Incorporated operates in the Biotechnology industry, part of the Healthcare sector (United States).

Frequently Asked Questions

What is Ligand Pharmaceuticals Incorporated’s (LGND) StockRank?
MoatMap’s StockRank for Ligand Pharmaceuticals Incorporated (LGND) is 71/100, with a Buy signal. It is a composite of Quality (64), Value (23), and Momentum (79), each scored against its sector. The composite is then ranked across MoatMap’s universe of 24,000+ stocks.
Does Ligand Pharmaceuticals Incorporated have an economic moat?
Ligand Pharmaceuticals Incorporated (LGND) has a Quality factor score of 64/100. The Quality factor combines ROIC, Piotroski F-Score, and leverage: the financial fingerprints of a durable competitive advantage. A Quality score above 70 typically indicates a company with the characteristics of a moated business.
Is Ligand Pharmaceuticals Incorporated a buy, hold, or sell?
MoatMap’s current signal for Ligand Pharmaceuticals Incorporated (LGND) is Buy, based on a StockRank of 71/100. Signals are derived mechanically from the StockRank composite and should be one input among many; combine with your own thesis on management, competitive position, and valuation.
What sector is Ligand Pharmaceuticals Incorporated in?
Ligand Pharmaceuticals Incorporated (LGND) operates in the Healthcare sector, specifically the Biotechnology industry (United States).