MGTX

HoldUnloved Quality

MeiraGTx Holdings plc · Healthcare · United States · $885M cap · $9.2M/day traded

$9.18 -0.3% · close 26 Oct · scored 27 Oct

Unloved Quality: Strong and cheap; the market has not turned yet.

56
StockRank
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Quality
59
Value
56
Momentum
35

As of 27 Oct 2026, MoatMap's StockRank for MeiraGTx Holdings plc (MGTX) is 56/100, ranked against 24,000+ stocks in 35 markets (Quality 59, Value 56, Momentum 35, each scored against its sector).

Does StockRank work? Each month we publish how every decile did, whichever way it went. See the record →

P/E (TTM)
10.7x
peers 27.3x
ROE
72.2%
peers -30.5%
D/E
0.5x
peers 0.2x
Dividend %
—
trailing yield

ABOUT MEIRAGTX HOLDINGS PLC

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MeiraGTx Holdings plc is a clinical-stage gene therapy company focused on developing and commercializing novel treatments for inherited diseases, with programs in ophthalmology, salivary gland disorders, and Parkinson's disease. The company differentiates itself with its proprietary gene therapy platforms and a vertically integrated approach, including its own GMP manufacturing facility. This strategic integration supports control over its development pipeline for high-unmet-need indications.

FINANCIAL SUMMARY (USD)

Year20212022202320242025CAGRTTM2026E2027EFwd CAGR
Revenue37.7M15.9M14.0M33.3M81.4M21.2%397.5M337.1M66.9M-9.4%
EPS-1.80-2.87-1.49-2.12-1.42—0.860.51-1.53—
Shares44.5M48.5M63.6M78.4M81.1M+82.1%96.0M———
Debt23.7M92.2M89.3M84.8M88.7M39.0%112.3M———
Equity185.4M117.7M138.2M67.8M-5.8M-28.5%————
Op CF-10.5M-73.1M-105.4M-104.5M-46.4M—13.7M———
Inv CF-61.7M-45.0M34.0M23.5M-4.1M—————
Fin CF1.7M95.2M84.0M54.5M12.3M—————
Loading 1Y...
PRICE (1Y) · USD-28.1%
9.210.211.212.213.315 Sep6 Oct26 Oct
SMA 50SMA 200

Price checkNo clear trendExperimental

No clear trend: not near its 52-week low, and not in a steady uptrend.

SwingsVery bumpy

Swung more than 72% of stocks we rank over the past year (58% a year).

How this is worked out

StockRank judges the business. The price check reads only the chart: it is the price side of the Momentum score, in words.

The rules: Still falling is a new 52-week low in the last two weeks, at least 25% below the high. Finding a floor is no new low since. Turning up is 20 or more trading days without a new low, at least 10% off it, and back above a rising 50-day average. In an uptrend is above the 200-day average and within 15% of the high.

In 2,112 US drawdowns since 2001, buying while the price was still falling was followed by a further 20% drop 42% of the time. Waiting for a turn like this one cut that to 33%, at about 7% higher prices and with no better returns. Part of that cut is simply not buying: 13% of falls never turned, and waiting kept those out. Among turns that were bought, 38% still fell another 20%, and 33% of turns were followed by a new low within six months. The benefit was largest in crashes such as 2008 and 2020.

What it measures: day-to-day price moves over the past year, as a yearly figure, ranked against every stock we cover. Very calm under 20% a year, Calm 20 to 30%, Average 30 to 40%, Bumpy 40 to 55%, Very bumpy above that.

What we found: across about 13,500 stocks in 34 markets (2002 to 2025), past swings were a good guide to the next year's, and bumpier stocks fell further. How much further changed too much between eras to put a number on it.

Calm is not safe: a calm stock can still slide steadily.

Rules fixed before any data was fetched. Describes the chart, not a recommendation.

Close
$9.18
RSI (14)
34.5
52-Week Range-40.2% from high
Low $6.62High $15.35

SCORE BREAKDOWN

Quality
59
ROIC
-89.1%8.0
ROE
72.2%98.5
GP/Assets
159.3%99.7
Op. Margin
76.0%99.2
FCF/Assets
1.4%51.1
Piotroski
549.3
Int. Cover
-9.0x22.6
D/E Ratio
0.52x28.1
Current Ratio
3.76x63.9
Value
56
P/E (TTM)
10.7x86.3
EV/EBITDA
4.4x94.0
P/FCF
253.1x5.4
P/B
4.0x32.1
P/S
2.2x63.0
Div Yield
—N/A
Momentum
35
52W High %
60%40.1
RS 6M
-6%55.9
SMA 50/200
1.18x86.9
EPS Rev 4W
-9.7%4.0
EPS Rev 12W
-11.6%11.5
EPS Improve
-277%1.9
Q Growth
—N/A

FUNDAMENTALS

Market Cap
$885M
P/E (Forward)
-6.0x
Gross Margin
97.9%

SECTOR PEERS

Closest peers in Healthcare, ranked by industry match, size, and score similarity. Cross-listings of MGTX are excluded.

TickerCompanyMkt CapStockRankSignal
MGTXMeiraGTx Holdings plc(you)$885M56Hold
MDXGMiMedx Group, Inc.$571M62Hold
OABIOmniAb, Inc.$678M43Hold
SEPNSepterna, Inc.$1.9B52Hold
FENCFennec Pharmaceuticals Inc.$353M58Hold
VCELVericel Corporation$2.2B59Hold
FTREFortrea Holdings Inc.$2.2B60Hold
OMEROmeros Corporation$1.2B39Hold
SGMTSagimet Biosciences Inc.$679M37Hold
GYREGyre Therapeutics, Inc.$620M38Hold

Peer medians: ROE -30.5% · P/E 27.3x · Gross margin 63.3%

Company Deep Dive

Business segments breakdown, earnings transcript analysis, management credibility scoring, competitive landscape, and scenario modelling.

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MeiraGTx Holdings plc (MGTX): Stock Score Summary

MeiraGTx Holdings plc (MGTX) has a MoatMap StockRank of 56/100 based on Quality (59/100), Value (56/100), and Momentum (35/100) factor scores. The current signal is HOLD.

MeiraGTx Holdings plc is a clinical-stage gene therapy company focused on developing and commercializing novel treatments for inherited diseases, with programs in ophthalmology, salivary gland disorders, and Parkinson's disease. The company differentiates itself with its proprietary gene therapy platforms and a vertically integrated approach, including its own GMP manufacturing facility. This strategic integration supports control over its development pipeline for high-unmet-need indications.

Key Financial Metrics

Price$9.18
Market Cap$885M
P/E (TTM)10.71
P/E (Forward)-6.04
Price/Book4.02
Return on Equity72.2%
Return on Invested Capital-89.1%
Debt/Equity0.52x
Gross Margin97.9%
Operating Margin76.0%
Revenue Growth8608.6%
Free Cash Flow$3M

MeiraGTx Holdings plc operates in the Biotechnology industry, part of the Healthcare sector (United States).

Frequently Asked Questions

What is MeiraGTx Holdings plc’s (MGTX) StockRank?
MoatMap’s StockRank for MeiraGTx Holdings plc (MGTX) is 56/100, with a Hold signal. It is a composite of Quality (59), Value (56), and Momentum (35), each scored against its sector. The composite is then ranked across MoatMap’s universe of 24,000+ stocks.
Does MeiraGTx Holdings plc have an economic moat?
MeiraGTx Holdings plc (MGTX) has a Quality factor score of 59/100. The Quality factor combines ROIC, Piotroski F-Score, and leverage: the financial fingerprints of a durable competitive advantage. A Quality score above 70 typically indicates a company with the characteristics of a moated business.
Is MeiraGTx Holdings plc a buy, hold, or sell?
MoatMap’s current signal for MeiraGTx Holdings plc (MGTX) is Hold, based on a StockRank of 56/100. Signals are derived mechanically from the StockRank composite and should be one input among many; combine with your own thesis on management, competitive position, and valuation.
What sector is MeiraGTx Holdings plc in?
MeiraGTx Holdings plc (MGTX) operates in the Healthcare sector, specifically the Biotechnology industry (United States).