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SEPN

HOLD

Septerna, Inc. · Healthcare · United States · $1.5B · Avg Vol: $17M/d

36
StockRank
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Q
45
V
25
M
58
P/E (TTM)
ROE
-9.3%
D/E
0.1x
Dividend %

COMPANY DESCRIPTION

Septerna, Inc. is a biotechnology company focused on discovering and developing novel small molecule medicines targeting G protein-coupled receptors (GPCRs). It leverages a proprietary drug discovery platform designed to identify new small molecule candidates for challenging GPCR targets, aiming to address unmet medical needs. Septerna is a clinical-stage biotechnology company with a specialized focus on GPCR drug discovery, utilizing a unique platform to unlock new therapeutic avenues.

FINANCIAL SUMMARY (USD)

Year2022202320242025CAGRTTM2026E2027EFwd CAGR
Revenue00.2M1.1M46.0M1644.5%72.3M76.9M65.8M19.7%
EPS-1.420.03-7.26-1.10-0.77-1.84-2.66
Shares42.0M42.0M44.4M44.8M+6.7%45.1M
Debt0.7M12.6M25.5M23.6M221.6%23.1M
Equity-44.2M-38.4M420.0M381.9M-9.1%
Op CF-23.3M-38.7M-67.5M110.2M107.9M
Inv CF-1.3M22.1M-160.6M-229.4M
Fin CF30.1M74.5M377.8M1.7M
Loading 1Y...
PRICE (1Y)-6.8%
31.5633.1334.7036.2737.84Jun 12Jul 7Jul 27
SMA 50SMA 200
Close
$33.49
RSI (14)
50.1
52W High
$38.04
From 52W High
0.9%

SCORE BREAKDOWN

Quality
45
ROIC
-15.9%32.1
ROE
-9.3%37.1
GP/Assets
12.1%31.1
Op. Margin
-50.1%21.5
FCF/Assets
4.0%64.8
Piotroski
559.8
Int. Cover
N/A
D/E Ratio
0.06x69.6
Current Ratio
4.71x68.9
Value
25
P/E (TTM)
N/A
EV/EBITDA
-16.9x25.0
P/FCF
62.1x20.9
P/B
3.8x35.3
P/S
20.1x17.2
Div Yield
N/A
Momentum
58
52W High %
88%83.2
RS 6M
18%85.4
SMA 50/200
1.21x89.4
EPS Rev 4W
0.0%62.6
EPS Rev 12W
-36.7%4.3
EPS Improve
-245%1.9
Q Growth
N/A

FUNDAMENTALS

Market Cap
$1.5B
P/E (Forward)
-12.1x
Gross Margin
100.0%

SECTOR PEERS

Closest peers in Healthcare, ranked by industry match, size, and score similarity. Cross-listings of SEPN are excluded.

TickerCompanyMkt CapStockRankSignal
SEPNSepterna, Inc.(you)$1.5B36HOLD
SRPTSarepta Therapeutics, Inc.$1.7B36HOLD
VIRVir Biotechnology, Inc.$1.5B32SELL
NVAXNovavax, Inc.$1.2B37HOLD
DMRADamora Therapeutics, Inc.$1.8B34SELL
ADMAADMA Biologics, Inc.$1.9B35HOLD
XNCRXencor, Inc.$1.4B30SELL
JBIOJade Biosciences, Inc.$1.2B33SELL
BCAXBicara Therapeutics Inc.$1.8B32SELL
AVBPArriVent BioPharma, Inc.$1.5B29SELL

Peer medians: ROE -25.6% · P/E 27.6x · Gross margin 50.5%

Septerna, Inc. (SEPN) — Stock Score Summary

Septerna, Inc. (SEPN) has a MoatMap StockRank of 36/100 based on Quality (45/100), Value (25/100), and Momentum (58/100) factor scores. The current signal is HOLD.

Septerna, Inc. is a biotechnology company focused on discovering and developing novel small molecule medicines targeting G protein-coupled receptors (GPCRs). It leverages a proprietary drug discovery platform designed to identify new small molecule candidates for challenging GPCR targets, aiming to address unmet medical needs. Septerna is a clinical-stage biotechnology company with a specialized focus on GPCR drug discovery, utilizing a unique platform to unlock new therapeutic avenues.

Key Financial Metrics

Price$33.49
Market Cap$1.5B
P/E (Forward)-12.11
Price/Book3.82
Return on Equity-9.3%
Return on Invested Capital-15.9%
Debt/Equity0.06x
Gross Margin100.0%
Operating Margin-50.1%
Revenue Growth12011.0%
Free Cash Flow$24M

Septerna, Inc. operates in the Biotechnology industry, part of the Healthcare sector (United States).

Frequently Asked Questions

What is Septerna, Inc.’s (SEPN) StockRank?
MoatMap’s StockRank for Septerna, Inc. (SEPN) is 36/100, with a Hold signal. It is a composite of Quality (45), Value (25), and Momentum (58) factor ranks across MoatMap’s 20,000+ stock universe.
Does Septerna, Inc. have an economic moat?
Septerna, Inc. (SEPN) has a Quality factor score of 45/100. The Quality factor combines ROIC, Piotroski F-Score, and leverage — the financial fingerprints of a durable competitive advantage. A Quality score above 70 typically indicates a company with the characteristics of a moated business.
Is Septerna, Inc. a buy, hold, or sell?
MoatMap’s current signal for Septerna, Inc. (SEPN) is Hold, based on a StockRank of 36/100. Signals are derived mechanically from the StockRank composite and should be one input among many — combine with your own thesis on management, competitive position, and valuation.
What sector is Septerna, Inc. in?
Septerna, Inc. (SEPN) operates in the Healthcare sector, specifically the Biotechnology industry (United States).