SNDX

Strong SellSinker

Syndax Pharmaceuticals, Inc. · Healthcare · United States · $1.2B cap · $31.6M/day traded

$13.22 -1.3% · close 26 Oct · scored 27 Oct

Sinker: Weak, expensive and falling. Nothing here to keep it afloat.

2
StockRank
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Quality
14
Value
23
Momentum
25

As of 27 Oct 2026, MoatMap's StockRank for Syndax Pharmaceuticals, Inc. (SNDX) is 2/100, ranked against 24,000+ stocks in 35 markets (Quality 14, Value 23, Momentum 25, each scored against its sector).

Does StockRank work? Each month we publish how every decile did, whichever way it went. See the record →

P/E (TTM)
—
peers 27.2x
ROE
-255.9%
peers -30.1%
D/E
39.0x
peers 0.2x
Dividend %
—
trailing yield

ABOUT SYNDAX PHARMACEUTICALS, INC.

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Syndax Pharmaceuticals, Inc. is a clinical-stage oncology company focused on developing and commercializing innovative therapies for cancer. Its pipeline includes differentiated small molecules and biologics targeting critical pathways in tumor biology and immune response, such as menin inhibition and CD73 blockade. Syndax's strong focus on unmet needs in difficult-to-treat cancers, coupled with its robust clinical development programs, positions it as a specialized player in the competitive oncology drug development landscape.

FINANCIAL SUMMARY (USD)

Year2022202320242025CAGRTTM2026E2027EFwd CAGR
Revenue0023.7M172.4M627.8%252.3M314.1M—82.3%
EPS-2.46-2.98-3.72-3.29—-2.52-1.98-0.84—
Shares68.1M84.8M85.7M87.4M+28.3%89.3M———
Debt1.2M1.6M345.7M345.4M567.6%589.4M———
Equity467.4M554.2M288.1M64.6M-48.3%————
Op CF-133.7M-160.6M-274.9M-323.0M—-220.6M———
Inv CF-186.2M117.6M-219.8M290.0M—————
Fin CF172.3M264.1M353.4M13.7M—————
Loading 1Y...
PRICE (1Y) · USD-26.9%
12.914.415.817.318.815 Sep6 Oct26 Oct
SMA 50SMA 200

Price checkStill fallingExperimental

Made a new 52-week low 5 trading days ago, 48% below its 52-week high. The fall has not stopped yet.

SwingsBumpy

Swung more than 66% of stocks we rank over the past year (52% a year).

How this is worked out

StockRank judges the business. The price check reads only the chart: it is the price side of the Momentum score, in words.

The rules: Still falling is a new 52-week low in the last two weeks, at least 25% below the high. Finding a floor is no new low since. Turning up is 20 or more trading days without a new low, at least 10% off it, and back above a rising 50-day average. In an uptrend is above the 200-day average and within 15% of the high.

In 2,112 US drawdowns since 2001, buying while the price was still falling was followed by a further 20% drop 42% of the time. Waiting for a turn like this one cut that to 33%, at about 7% higher prices and with no better returns. Part of that cut is simply not buying: 13% of falls never turned, and waiting kept those out. Among turns that were bought, 38% still fell another 20%, and 33% of turns were followed by a new low within six months. The benefit was largest in crashes such as 2008 and 2020.

What it measures: day-to-day price moves over the past year, as a yearly figure, ranked against every stock we cover. Very calm under 20% a year, Calm 20 to 30%, Average 30 to 40%, Bumpy 40 to 55%, Very bumpy above that.

What we found: across about 13,500 stocks in 34 markets (2002 to 2025), past swings were a good guide to the next year's, and bumpier stocks fell further. How much further changed too much between eras to put a number on it.

Calm is not safe: a calm stock can still slide steadily.

Rules fixed before any data was fetched. Describes the chart, not a recommendation.

Close
$13.22
RSI (14)
16.0
52-Week Range-48.3% from high
Low $12.80High $25.59

SCORE BREAKDOWN

Quality
14
ROIC
-43.5%17.9
ROE
-255.9%2.9
GP/Assets
-3.8%7.1
Op. Margin
-54.9%19.9
FCF/Assets
-61.0%5.7
Piotroski
10.8
Int. Cover
-4.2x28.1
D/E Ratio
39.03x0.2
Current Ratio
6.77x80.4
Value
23
P/E (TTM)
—N/A
EV/EBITDA
-6.3x25.0
P/FCF
—N/A
P/B
79.3x0.8
P/S
4.7x40.6
Div Yield
—N/A
Momentum
25
52W High %
52%29.1
RS 6M
-44%14.5
SMA 50/200
0.87x25.0
EPS Rev 4W
-2.8%8.3
EPS Rev 12W
-64.7%0.6
EPS Improve
+67%63.9
Q Growth
—N/A

FUNDAMENTALS

Market Cap
$1.2B
P/E (Forward)
-16.0x
Gross Margin
96.0%

SECTOR PEERS

Closest peers in Healthcare, ranked by industry match, size, and score similarity. Cross-listings of SNDX are excluded.

TickerCompanyMkt CapStockRankSignal
SNDXSyndax Pharmaceuticals, Inc.(you)$1.2B2Strong Sell
AVLNAvalyn Pharma Inc.$1.2B7Strong Sell
INBXInhibrx Biosciences, Inc.$1.4B5Strong Sell
TSHATaysha Gene Therapies, Inc.$1.3B8Strong Sell
CTYCity Therapeutics, Inc.$1.0B6Strong Sell
LTGOLatigo Biotherapeutics, Inc.$996M6Strong Sell
OCULOcular Therapeutix, Inc.$1.4B7Strong Sell
ALMSAlumis Inc.$878M5Strong Sell
OBXObsidian Therapeutics, Inc.$864M6Strong Sell
RAPPRapport Therapeutics, Inc.$1.2B12Strong Sell

Peer medians: ROE -30.1% · P/E 27.2x · Gross margin 63.3%

Company Deep Dive

Business segments breakdown, earnings transcript analysis, management credibility scoring, competitive landscape, and scenario modelling.

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Syndax Pharmaceuticals, Inc. (SNDX): Stock Score Summary

Syndax Pharmaceuticals, Inc. (SNDX) has a MoatMap StockRank of 2/100 based on Quality (14/100), Value (23/100), and Momentum (25/100) factor scores. The current signal is STRONG SELL.

Syndax Pharmaceuticals, Inc. is a clinical-stage oncology company focused on developing and commercializing innovative therapies for cancer. Its pipeline includes differentiated small molecules and biologics targeting critical pathways in tumor biology and immune response, such as menin inhibition and CD73 blockade. Syndax's strong focus on unmet needs in difficult-to-treat cancers, coupled with its robust clinical development programs, positions it as a specialized player in the competitive oncology drug development landscape.

Key Financial Metrics

Price$13.22
Market Cap$1.2B
P/E (Forward)-15.97
Price/Book79.29
Return on Equity-255.9%
Return on Invested Capital-43.5%
Debt/Equity39.03x
Gross Margin96.0%
Operating Margin-54.9%
Revenue Growth91.8%
Free Cash Flow$-323M

Syndax Pharmaceuticals, Inc. operates in the Biotechnology industry, part of the Healthcare sector (United States).

Frequently Asked Questions

What is Syndax Pharmaceuticals, Inc.’s (SNDX) StockRank?
MoatMap’s StockRank for Syndax Pharmaceuticals, Inc. (SNDX) is 2/100, with a Strong Sell signal. It is a composite of Quality (14), Value (23), and Momentum (25), each scored against its sector. The composite is then ranked across MoatMap’s universe of 24,000+ stocks.
Does Syndax Pharmaceuticals, Inc. have an economic moat?
Syndax Pharmaceuticals, Inc. (SNDX) has a Quality factor score of 14/100. The Quality factor combines ROIC, Piotroski F-Score, and leverage: the financial fingerprints of a durable competitive advantage. A Quality score above 70 typically indicates a company with the characteristics of a moated business.
Is Syndax Pharmaceuticals, Inc. a buy, hold, or sell?
MoatMap’s current signal for Syndax Pharmaceuticals, Inc. (SNDX) is Strong Sell, based on a StockRank of 2/100. Signals are derived mechanically from the StockRank composite and should be one input among many; combine with your own thesis on management, competitive position, and valuation.
What sector is Syndax Pharmaceuticals, Inc. in?
Syndax Pharmaceuticals, Inc. (SNDX) operates in the Healthcare sector, specifically the Biotechnology industry (United States).