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ZYME

HOLDREMOVE

Zymeworks Inc. · Healthcare · United States · $1.9B · Avg Vol: $17M/d

40
StockRank
Q
33
V
35
M
64
P/E (TTM)
ROE
-42.0%
D/E
0.1x
Dividend %
AI CONVICTION THESIS

A clinical-stage biopharmaceutical company with volatile earnings and high R&D expenses. It does not possess the predictable cash flows, high ROIC, or established commercial moats required for our concentrated portfolio.

COMPANY DESCRIPTION

Zymeworks Inc. is a clinical-stage biopharmaceutical company dedicated to the development of next-generation, multifunctional biotherapeutics, with a primary focus on antibody-drug conjugates (ADCs) and multispecific antibodies for oncology. The company's competitive moat is established by its proprietary therapeutic platforms, including Azymetric and EFECT, which have been validated through lucrative licensing agreements with global pharmaceutical giants. These strategic collaborations provide Zymeworks with substantial non-dilutive funding while accelerating the clinical development of its diverse oncology pipeline.

FINANCIAL SUMMARY (USD)

Year2022202320242025CAGR
Revenue412.5M76.0M76.3M106.0M-36.4%
EPS1.91-1.72-1.62-1.08
Shares63.1M70.1M69.0M75.2M+19.2%
Debt28.1M26.7M18.5M18.3M-13.4%
Equity493.0M464.8M338.8M268.5M-18.3%
Op CF144.1M-118.3M-110.1M-33.0M
Inv CF-53.8M-207.3M38.8M26.7M
Fin CF108.6M81.9M-20.4M-18.6M
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PRICE (1Y)-13.0%
22.4923.5224.5525.5726.60May 7May 29Jun 18
SMA 50SMA 200
Close
$23.14
RSI (14)
34.1
52W High
$29.75
From 52W High
0.8%

SCORE BREAKDOWN

Quality
33
ROIC
-30.4%22.7
ROE
-42.0%20.3
GP/Assets
-15.7%5.6
Op. Margin
-1956.7%5.0
FCF/Assets
-13.1%24.2
Piotroski
439.0
Int. Cover
N/A
D/E Ratio
0.10x65.2
Current Ratio
10.82x88.2
Value
35
P/E (TTM)
N/A
EV/EBITDA
-12.3x83.4
P/FCF
N/A
P/B
6.4x18.5
P/S
20.7x16.8
Div Yield
N/A
Momentum
64
52W High %
78%69.9
RS 6M
-21%55.0
SMA 50/200
1.12x82.6
EPS Rev 4W
+48.1%98.1
EPS Rev 12W
N/A
EPS Improve
+150%82.3
Q Growth
N/A

FUNDAMENTALS

Market Cap
$1.9B
P/E (Forward)
33.5x
Gross Margin
-67.0%

SECTOR PEERS

Closest peers in Healthcare, ranked by industry match, size, and score similarity. Cross-listings of ZYME are excluded.

TickerCompanyMkt CapStockRankSignal
ZYMEZymeworks Inc.(you)$1.9B40HOLD
CAPRCapricor Therapeutics, Inc.$1.7B40HOLD
TYRATyra Biosciences, Inc.$1.9B38HOLD
SIONSionna Therapeutics, Inc.$1.9B36HOLD
STOKStoke Therapeutics, Inc.$2.0B36HOLD
RAPPRapport Therapeutics, Inc.$1.9B45HOLD
AGIOAgios Pharmaceuticals, Inc.$1.8B35SELL
IOVAIovance Biotherapeutics, Inc.$1.9B47HOLD
ADMAADMA Biologics, Inc.$1.8B33SELL
DFTXDefinium Therapeutics, Inc.$2.6B38HOLD

Peer medians: ROE -22.4% · P/E 25.3x · Gross margin 44.3%

Zymeworks Inc. (ZYME) — Stock Score Summary

Zymeworks Inc. (ZYME) has a MoatMap StockRank of 40/100 based on Quality (33/100), Value (35/100), and Momentum (64/100) factor scores. The current signal is HOLD. A clinical-stage biopharmaceutical company with volatile earnings and high R&D expenses. It does not possess the predictable cash flows, high ROIC, or established commercial moats required for our concentrated portfolio.

Zymeworks Inc. is a clinical-stage biopharmaceutical company dedicated to the development of next-generation, multifunctional biotherapeutics, with a primary focus on antibody-drug conjugates (ADCs) and multispecific antibodies for oncology. The company's competitive moat is established by its proprietary therapeutic platforms, including Azymetric and EFECT, which have been validated through lucrative licensing agreements with global pharmaceutical giants. These strategic collaborations provide Zymeworks with substantial non-dilutive funding while accelerating the clinical development of its diverse oncology pipeline.

Key Financial Metrics

Price$23.14
Market Cap$1.9B
P/E (Forward)33.48
Price/Book6.36
Return on Equity-42.0%
Return on Invested Capital-30.4%
Debt/Equity10.42
Gross Margin-67.0%
Operating Margin-1956.7%
Revenue Growth-91.1%
Free Cash Flow$-46M

Zymeworks Inc. operates in the Biotechnology industry, part of the Healthcare sector (United States).

Frequently Asked Questions

What is Zymeworks Inc.’s (ZYME) StockRank?
MoatMap’s StockRank for Zymeworks Inc. (ZYME) is 40/100, with a Hold signal. It is a composite of Quality (33), Value (35), and Momentum (64) factor ranks across MoatMap’s 20,000+ stock universe.
Does Zymeworks Inc. have an economic moat?
Zymeworks Inc. (ZYME) has a Quality factor score of 33/100. The Quality factor combines ROIC, Piotroski F-Score, and leverage — the financial fingerprints of a durable competitive advantage. A Quality score above 70 typically indicates a company with the characteristics of a moated business.
Is Zymeworks Inc. a buy, hold, or sell?
MoatMap’s current signal for Zymeworks Inc. (ZYME) is Hold, based on a StockRank of 40/100. Signals are derived mechanically from the StockRank composite and should be one input among many — combine with your own thesis on management, competitive position, and valuation.
What sector is Zymeworks Inc. in?
Zymeworks Inc. (ZYME) operates in the Healthcare sector, specifically the Biotechnology industry (United States).