ACIU

Sinker

AC Immune SA · Healthcare · Switzerland · $299M cap · $449K/day traded

$2.14 -5.3% · close 12 Nov · scored 13 Nov

Sinker: Weak business, rich price and weak momentum. Nothing here to keep it afloat.

12
Score
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Quality
17
Value
27
Momentum
44

As of 13 Nov 2026, the MoatMap Score for AC Immune SA (ACIU) is 12/100, ranked against 25,000+ stocks in 38 markets (Quality 17, Value 27, Momentum 44, each scored against its sector).

Does the score work? Each tenth of the ranking, tracked monthly. See the record →

P/E (TTM)
—
peers 37.4x
ROE
-78.5%
peers 10.7%
D/E
0.1x
peers 0.4x
Dividend %
—
trailing yield

ABOUT AC IMMUNE SA

Read

AC Immune SA is a clinical-stage biopharmaceutical company dedicated to discovering, developing, and commercializing precision medicines and diagnostics for neurodegenerative diseases, focusing on conditions like Alzheimer's and Parkinson's. The company leverages proprietary technology platforms like Morphomer and SupraAntigen to target misfolded proteins, a key pathological hallmark of these diseases. AC Immune's competitive edge is its specialized R&D in this complex field, aiming to bring innovative solutions to areas of high unmet medical need.

FINANCIAL SUMMARY (USD)

Reported in CHF

Year2022202320242025CAGRTTM2026E2027EFwd CAGR
Revenue4.1M16.5M31.0M4.3M1.5%21.5M43.6M105.5M395.6%
EPS-0.89-0.71-0.58-0.84—-0.44-0.500.60—
Shares83.6M99.2M100.4M101.7M+21.7%99.4M———
Debt3.0M4.1M6.0M5.7M23.6%5.0M———
Equity183.1M190.5M124.3M56.7M-32.4%————
Op CF-77.1M-67.3M74.8M-83.6M—-61.9M———
Inv CF24.9M73.1M-119.7M76.7M—————
Fin CF-1.4M48.2M-1.3M-1.2M—————
PRICE (1Y) · USD-21.5%
2.12.22.42.62.72 Oct23 Oct12 Nov
SMA 50SMA 200

Price checkStill fallingExperimental

Made a new 52-week low 8 trading days ago, 45% below its 52-week high. The fall has not stopped yet.

SwingsVery bumpy

Swung more than 80% of stocks we rank over the past year (volatility 67% a year).

How this is worked out

The Price check reads only the chart, the price side of the Momentum score in words; it is not the MoatMap Score.

  • Still falling (this stock): It set a new 52-week low in the last two weeks, after a deep fall.
  • Finding a floor: It fell hard, but has set no new low for more than two weeks.
  • Turning up: It has climbed off its low and is back above a rising 50-day average.
  • In an uptrend: It is near its 52-week high and above its 200-day average.
  • No clear trend: None of the above: no recent deep fall and no steady climb.
  • No read yet: Not enough price history yet: it needs a year of trading.

In past US falls, waiting for Turning up cut the chance of another 20% drop from 42% to 33%. Returns were no better, and 33% of turns failed.

The exact rules

Still falling is a new 52-week low in the last two weeks, at least 25% below the high, with the low set after the high. Finding a floor is the same fall with no new low in the last two weeks. Turning up is 20 or more trading days without a new low, at least 10% off it, and back above a rising 50-day average. In an uptrend is above the 200-day average, with the 50-day average above the 200-day, and within 15% of the high. No clear trend is everything else. No read yet is under 252 trading days of history, or missing data. A new state shows once it has held for three trading days.

In 2,112 US drawdowns since 2001, buying while the price was still falling was followed by a further 20% drop 42% of the time. Waiting for a turn (the Turning up rule above) cut that to 33%, at about 7% higher prices and with no better returns. Part of that cut is simply not buying: 13% of falls never turned, and waiting kept those out. Among turns that were bought, 38% still fell another 20%, and 33% of turns were followed by a new low within six months. The benefit was largest in crashes such as 2008 and 2020.

What it measures: how much the price moved day to day over the past year, scaled to a yearly figure (annualised volatility) and ranked against every stock we cover. Very calm under 20% a year, Calm 20 to 30%, Average 30 to 40%, Bumpy 40 to 55%, Very bumpy above that.

What we found: across about 13,500 stocks in 34 markets (2002 to 2025), past swings were a good guide to the next year's, and bumpier stocks fell further. How much further changed too much between eras to put a number on it.

Calm is not safe: a calm stock can still slide steadily.

Rules fixed before any data was fetched. Describes the chart, not a recommendation.

Close
$2.14
RSI (14)
41.5
52-Week Range-45.1% from high
Low $2.02High $3.90

SCORE BREAKDOWN

Quality
17
ROIC
-60.1%12.8
ROE
-78.5%11.8
GP/Assets
-18.4%4.6
Op. Margin
7.9%57.3
FCF/Assets
-45.5%9.0
Piotroski
12.3
Int. Cover
-50.0x5.8
D/E Ratio
0.12x59.8
Current Ratio
0.93x8.9
Value
27
P/E (TTM)
—N/A
EV/EBITDA
-3.0x25.0
P/FCF
—N/A
P/B
3.4x36.9
P/S
10.3x22.6
Div Yield
—N/A
Momentum
44
52W High %
55%33.4
RS 6M
-25%23.9
SMA 50/200
0.94x45.4
EPS Rev 4W
+0.8%81.8
EPS Rev 12W
-1.9%25.1
EPS Improve
+237%90.3
Q Growth
—N/A

FUNDAMENTALS

Market Cap
$299M
P/E (Forward)
3.7x
Gross Margin
—

SECTOR PEERS

Closest peers in Healthcare, ranked by industry match, size, and score similarity. Cross-listings of ACIU are excluded.

TickerCompanyMkt CapScore
ACIUAC Immune SA(you)$299M12
BIOV.SWBioVersys AG$175M13
OCSOculis Holding AG$487M8
SANN.SWSanthera Pharmaceuticals Holding AG$257M25
MOLNMolecular Partners AG$165M17
MLTXMoonLake Immunotherapeutics$1.0B8
IDIA.SWIdorsia Ltd$1.4B15
XLS.SWXlife Sciences AG$61M7
PHVSPharvaris N.V.$2.2B19
CRSPCRISPR Therapeutics AG$4.8B11

Peer medians: ROE 10.7% · P/E 37.4x · Gross margin 59.2%

Company Deep Dive

A 10,000-word report: the business and its segments, what management promised on earnings calls and whether it delivered, the competition, and how things could turn out.

Request Deep Dive(50 Feathers)

AC Immune SA (ACIU): Stock Score Summary

AC Immune SA (ACIU) has a MoatMap Score of 12/100 based on Quality (17/100), Value (27/100), and Momentum (44/100) factor scores.

AC Immune SA is a clinical-stage biopharmaceutical company dedicated to discovering, developing, and commercializing precision medicines and diagnostics for neurodegenerative diseases, focusing on conditions like Alzheimer's and Parkinson's. The company leverages proprietary technology platforms like Morphomer and SupraAntigen to target misfolded proteins, a key pathological hallmark of these diseases. AC Immune's competitive edge is its specialized R&D in this complex field, aiming to bring innovative solutions to areas of high unmet medical need.

Director dealings

From 2 Jan 2026 to 12 Nov 2026, MoatMap's records hold 2 sales and 1 purchase of AC Immune SA (ACIU) shares by its directors. The largest: Pfeifer Andrea bought 10,000 shares at $3.14 on 15 Apr 2026 (about $31K).

  • 15 May 2026: Pfeifer Andrea sold 10,000 shares at $2.79 (about $28K)
  • 15 Apr 2026: Pfeifer Andrea bought 10,000 shares at $3.14 (about $31K)
  • 15 Apr 2026: Pfeifer Andrea sold 10,000 shares at $3.14 (about $31K)
ACIU insider filings, last 180 days

Key Financial Metrics

Price$2.14
Market Cap$299M
P/E (Forward)3.71
Price/Book3.40
Return on Equity-78.5%
Return on Invested Capital-60.1%
Debt/Equity0.12x
Operating Margin7.9%
Revenue Growth1057.2%
Free Cash Flow$-86M

AC Immune SA operates in the Biotechnology industry, part of the Healthcare sector (Switzerland).

Frequently Asked Questions

What is AC Immune SA’s (ACIU) MoatMap Score?
The MoatMap Score for AC Immune SA (ACIU) is 12/100. It is a composite of Quality (17), Value (27), and Momentum (44), each scored against its sector. The composite is then ranked across MoatMap’s universe of 25,000+ stocks.
Does AC Immune SA have an economic moat?
AC Immune SA (ACIU) has a Quality factor score of 17/100. Quality blends several measures of profitability and financial strength, led by gross profit to assets, return on invested capital and free cash flow to assets. A high score describes the financial record a durable advantage tends to leave; it does not prove a moat.
What sector is AC Immune SA in?
AC Immune SA (ACIU) operates in the Healthcare sector, specifically the Biotechnology industry (Switzerland).