CRSP

Sinker

CRISPR Therapeutics AG · Healthcare · Switzerland · $4.8B cap · $69.6M/day traded

$42.62 -6.8% · close 12 Nov · scored 13 Nov

Sinker: Weak business, rich price and weak momentum. Nothing here to keep it afloat.

11
Score
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Quality
23
Value
26
Momentum
36

As of 13 Nov 2026, the MoatMap Score for CRISPR Therapeutics AG (CRSP) is 11/100, ranked against 25,000+ stocks in 38 markets (Quality 23, Value 26, Momentum 36, each scored against its sector).

Does the score work? Each tenth of the ranking, tracked monthly. See the record →

P/E (TTM)
—
peers 37.4x
ROE
-25.6%
peers 10.7%
D/E
0.5x
peers 0.4x
Dividend %
—
trailing yield

ABOUT CRISPR THERAPEUTICS AG

Read

CRISPR Therapeutics AG is a leading gene editing company leveraging its proprietary CRISPR/Cas9 technology to develop transformative gene-based medicines for serious genetic diseases and cancers. As a pioneer in the field, it holds foundational intellectual property and has brought the first CRISPR-based gene therapy, Casgevy, to market, establishing a significant early competitive advantage.

FINANCIAL SUMMARY (USD)

Year2022202320242025CAGRTTM2026E2027EFwd CAGR
Revenue0.4M370.0M35.0M0796.0%25.2M35.4M133.4M56.2%
EPS-8.36-1.94-4.34-6.47—-4.73-4.54-3.69—
Shares78.5M80.0M85.7M95.9M+22.1%97.0M———
Debt244.0M238.6M223.7M206.7M-5.4%779.8M———
Equity1.9B1.9B1.9B1.9B0.8%————
Op CF-495.7M-260.4M-142.8M-345.0M—-374.6M———
Inv CF-258.7M374.6M-280.5M-31.8M—————
Fin CF38.6M62.7M332.0M426.0M—————
PRICE (1Y) · USD-23.1%
42.646.350.053.757.32 Oct23 Oct12 Nov
SMA 50SMA 200

Price checkNo clear trendExperimental

No clear trend: not near its 52-week low, and not in a steady uptrend.

SwingsVery bumpy

Swung more than 73% of stocks we rank over the past year (volatility 58% a year).

How this is worked out

The Price check reads only the chart, the price side of the Momentum score in words; it is not the MoatMap Score.

  • Still falling: It set a new 52-week low in the last two weeks, after a deep fall.
  • Finding a floor: It fell hard, but has set no new low for more than two weeks.
  • Turning up: It has climbed off its low and is back above a rising 50-day average.
  • In an uptrend: It is near its 52-week high and above its 200-day average.
  • No clear trend (this stock): None of the above: no recent deep fall and no steady climb.
  • No read yet: Not enough price history yet: it needs a year of trading.

In past US falls, waiting for Turning up cut the chance of another 20% drop from 42% to 33%. Returns were no better, and 33% of turns failed.

The exact rules

Still falling is a new 52-week low in the last two weeks, at least 25% below the high, with the low set after the high. Finding a floor is the same fall with no new low in the last two weeks. Turning up is 20 or more trading days without a new low, at least 10% off it, and back above a rising 50-day average. In an uptrend is above the 200-day average, with the 50-day average above the 200-day, and within 15% of the high. No clear trend is everything else. No read yet is under 252 trading days of history, or missing data. A new state shows once it has held for three trading days.

In 2,112 US drawdowns since 2001, buying while the price was still falling was followed by a further 20% drop 42% of the time. Waiting for a turn (the Turning up rule above) cut that to 33%, at about 7% higher prices and with no better returns. Part of that cut is simply not buying: 13% of falls never turned, and waiting kept those out. Among turns that were bought, 38% still fell another 20%, and 33% of turns were followed by a new low within six months. The benefit was largest in crashes such as 2008 and 2020.

What it measures: how much the price moved day to day over the past year, scaled to a yearly figure (annualised volatility) and ranked against every stock we cover. Very calm under 20% a year, Calm 20 to 30%, Average 30 to 40%, Bumpy 40 to 55%, Very bumpy above that.

What we found: across about 13,500 stocks in 34 markets (2002 to 2025), past swings were a good guide to the next year's, and bumpier stocks fell further. How much further changed too much between eras to put a number on it.

Calm is not safe: a calm stock can still slide steadily.

Rules fixed before any data was fetched. Describes the chart, not a recommendation.

Close
$42.62
RSI (14)
36.5
52-Week Range-32.8% from high
Low $42.38High $63.45

SCORE BREAKDOWN

Quality
23
ROIC
-25.3%26.4
ROE
-25.6%26.7
GP/Assets
-19.7%4.5
Op. Margin
-934.3%6.9
FCF/Assets
-16.5%25.0
Piotroski
29.3
Int. Cover
—N/A
D/E Ratio
0.47x30.0
Current Ratio
16.21x94.3
Value
26
P/E (TTM)
—N/A
EV/EBITDA
-6.7x25.0
P/FCF
—N/A
P/B
2.9x42.2
P/S
192.9x4.8
Div Yield
—N/A
Momentum
36
52W High %
67%51.9
RS 6M
-17%32.9
SMA 50/200
1.00x60.4
EPS Rev 4W
-5.0%7.7
EPS Rev 12W
-5.3%17.0
EPS Improve
+22%37.6
Q Growth
—N/A

FUNDAMENTALS

Market Cap
$4.8B
P/E (Forward)
-13.6x
Gross Margin
—

SECTOR PEERS

Closest peers in Healthcare, ranked by industry match, size, and score similarity. Cross-listings of CRSP are excluded.

TickerCompanyMkt CapScore
CRSPCRISPR Therapeutics AG(you)$4.8B11
PHVSPharvaris N.V.$2.2B19
IDIA.SWIdorsia Ltd$1.4B15
MLTXMoonLake Immunotherapeutics$1.0B8
OCSOculis Holding AG$487M8
BANB.SWBachem Holding AG$7.5B50
ACIUAC Immune SA$299M12
BIOV.SWBioVersys AG$175M13
SANN.SWSanthera Pharmaceuticals Holding AG$257M25
MOLNMolecular Partners AG$165M17

Peer medians: ROE 10.7% · P/E 37.4x · Gross margin 59.2%

Company Deep Dive

A 10,000-word report: the business and its segments, what management promised on earnings calls and whether it delivered, the competition, and how things could turn out.

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CRISPR Therapeutics AG (CRSP): Stock Score Summary

CRISPR Therapeutics AG (CRSP) has a MoatMap Score of 11/100 based on Quality (23/100), Value (26/100), and Momentum (36/100) factor scores.

CRISPR Therapeutics AG is a leading gene editing company leveraging its proprietary CRISPR/Cas9 technology to develop transformative gene-based medicines for serious genetic diseases and cancers. As a pioneer in the field, it holds foundational intellectual property and has brought the first CRISPR-based gene therapy, Casgevy, to market, establishing a significant early competitive advantage.

Director dealings

From 2 Jan 2026 to 12 Nov 2026, MoatMap's records hold 23 sales and no purchases of CRISPR Therapeutics AG (CRSP) shares by its directors. The largest: Kulkarni Samarth sold 60,000 shares at $60.23 on 22 Jan 2026 (about $3.6M).

  • 19 Oct 2026: Kulkarni Samarth sold 47,837 shares at $49.78 (about $2.4M)
  • 14 Oct 2026: George Simeon sold 14,514 shares at $49.63 (about $720K)
  • 14 Oct 2026: KASINGER JAMES R. sold 1,040 shares at $49.26 (about $51K)
  • 14 Oct 2026: Kulkarni Samarth sold 4,098 shares at $49.26 (about $202K)
  • 6 Oct 2026: KASINGER JAMES R. sold 1,990 shares at $60.04 (about $119K)
CRSP insider filings, last 180 days

Key Financial Metrics

Price$42.62
Market Cap$4.8B
P/E (Forward)-13.56
Price/Book2.94
Return on Equity-25.6%
Return on Invested Capital-25.3%
Debt/Equity0.47x
Operating Margin-934.3%
Revenue Growth1325.1%
Free Cash Flow$-374M

CRISPR Therapeutics AG operates in the Biotechnology industry, part of the Healthcare sector (Switzerland).

Frequently Asked Questions

What is CRISPR Therapeutics AG’s (CRSP) MoatMap Score?
The MoatMap Score for CRISPR Therapeutics AG (CRSP) is 11/100. It is a composite of Quality (23), Value (26), and Momentum (36), each scored against its sector. The composite is then ranked across MoatMap’s universe of 25,000+ stocks.
Does CRISPR Therapeutics AG have an economic moat?
CRISPR Therapeutics AG (CRSP) has a Quality factor score of 23/100. Quality blends several measures of profitability and financial strength, led by gross profit to assets, return on invested capital and free cash flow to assets. A high score describes the financial record a durable advantage tends to leave; it does not prove a moat.
What sector is CRISPR Therapeutics AG in?
CRISPR Therapeutics AG (CRSP) operates in the Healthcare sector, specifically the Biotechnology industry (Switzerland).