LXEO

Strong SellSinker

Lexeo Therapeutics, Inc. · Healthcare · United States · $230M cap · $4.8M/day traded

$2.70 -3.6% · close 26 Oct · scored 27 Oct

Sinker: Weak, expensive and falling. Nothing here to keep it afloat.

10
StockRank
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Quality
31
Value
34
Momentum
19

As of 27 Oct 2026, MoatMap's StockRank for Lexeo Therapeutics, Inc. (LXEO) is 10/100, ranked against 24,000+ stocks in 35 markets (Quality 31, Value 34, Momentum 19, each scored against its sector).

Does StockRank work? Each month we publish how every decile did, whichever way it went. See the record →

P/E (TTM)
—
peers 27.2x
ROE
-46.8%
peers -30.1%
D/E
0.0x
peers 0.2x
Dividend %
—
trailing yield

ABOUT LEXEO THERAPEUTICS, INC.

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Lexeo Therapeutics, Inc. is a clinical-stage gene therapy company focused on developing therapies for genetically defined cardiovascular, CNS, and other rare diseases. It utilizes a proprietary AAV gene therapy platform to target specific genetic defects, aiming to deliver one-time corrective treatments. The company is a specialized biotech company innovating in the gene therapy space, focusing on precision medicine for serious and often debilitating conditions.

FINANCIAL SUMMARY (USD)

Year20212022202320242025CAGRTTM2026E2027EFwd CAGR
Revenue1.7M0.7M000-60.5%——6.1M56.4%
EPS-2.01-0.75-4.21-1.30-1.86—-1.02-1.20-1.37—
Shares25.2M78.5M78.5M78.5M73.0M+190.0%82.1M———
Debt013.5M11.6M9.9M7.9M-16.4%6.8M———
Equity-55.6M-113.0M113.5M116.8M246.7M47.4%————
Op CF-44.2M-54.6M-59.5M-81.2M-98.6M—-88.4M———
Inv CF-0.2M-0.9M-0.2M-94.1M-90.3M—————
Fin CF150.9M0.2M103.8M88.8M216.8M—————
Loading 1Y...
PRICE (1Y) · USD-34.6%
2.63.03.43.84.215 Sep6 Oct26 Oct
SMA 50SMA 200

Price checkStill fallingExperimental

Made a new 52-week low 5 trading days ago, 75% below its 52-week high. The fall has not stopped yet.

SwingsVery bumpy

Swung more than 83% of stocks we rank over the past year (71% a year).

How this is worked out

StockRank judges the business. The price check reads only the chart: it is the price side of the Momentum score, in words.

The rules: Still falling is a new 52-week low in the last two weeks, at least 25% below the high. Finding a floor is no new low since. Turning up is 20 or more trading days without a new low, at least 10% off it, and back above a rising 50-day average. In an uptrend is above the 200-day average and within 15% of the high.

In 2,112 US drawdowns since 2001, buying while the price was still falling was followed by a further 20% drop 42% of the time. Waiting for a turn like this one cut that to 33%, at about 7% higher prices and with no better returns. Part of that cut is simply not buying: 13% of falls never turned, and waiting kept those out. Among turns that were bought, 38% still fell another 20%, and 33% of turns were followed by a new low within six months. The benefit was largest in crashes such as 2008 and 2020.

What it measures: day-to-day price moves over the past year, as a yearly figure, ranked against every stock we cover. Very calm under 20% a year, Calm 20 to 30%, Average 30 to 40%, Bumpy 40 to 55%, Very bumpy above that.

What we found: across about 13,500 stocks in 34 markets (2002 to 2025), past swings were a good guide to the next year's, and bumpier stocks fell further. How much further changed too much between eras to put a number on it.

Calm is not safe: a calm stock can still slide steadily.

Rules fixed before any data was fetched. Describes the chart, not a recommendation.

Close
$2.70
RSI (14)
32.1
52-Week Range-75.4% from high
Low $2.55High $10.99

SCORE BREAKDOWN

Quality
31
ROIC
-34.6%21.7
ROE
-46.8%19.1
GP/Assets
-24.8%3.6
Op. Margin
0.0%38.6
FCF/Assets
-36.8%12.2
Piotroski
559.2
Int. Cover
-50.0x5.8
D/E Ratio
0.03x76.8
Current Ratio
13.89x92.0
Value
34
P/E (TTM)
—N/A
EV/EBITDA
-0.3x25.0
P/FCF
—N/A
P/B
0.9x84.6
P/S
—N/A
Div Yield
—N/A
Momentum
19
52W High %
25%6.7
RS 6M
-59%7.1
SMA 50/200
0.74x9.9
EPS Rev 4W
+0.3%74.3
EPS Rev 12W
-9.7%13.1
EPS Improve
-34%11.6
Q Growth
—N/A

FUNDAMENTALS

Market Cap
$230M
P/E (Forward)
-2.1x
Gross Margin
—

SECTOR PEERS

Closest peers in Healthcare, ranked by industry match, size, and score similarity. Cross-listings of LXEO are excluded.

TickerCompanyMkt CapStockRankSignal
LXEOLexeo Therapeutics, Inc.(you)$230M10Strong Sell
ZNTLZentalis Pharmaceuticals, Inc.$217M10Strong Sell
LRMRLarimar Therapeutics, Inc.$244M10Strong Sell
ALECAlector, Inc.$204M10Strong Sell
LYELLyell Immunopharma, Inc.$230M7Strong Sell
PYXSPyxis Oncology, Inc.$201M9Strong Sell
GLSIGreenwich LifeSciences, Inc.$235M7Strong Sell
CABACabaletta Bio, Inc.$249M13Strong Sell
RNACCartesian Therapeutics, Inc.$187M10Strong Sell
ELDNEledon Pharmaceuticals, Inc.$187M11Strong Sell

Peer medians: ROE -30.1% · P/E 27.2x · Gross margin 63.3%

Company Deep Dive

Business segments breakdown, earnings transcript analysis, management credibility scoring, competitive landscape, and scenario modelling.

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Lexeo Therapeutics, Inc. (LXEO): Stock Score Summary

Lexeo Therapeutics, Inc. (LXEO) has a MoatMap StockRank of 10/100 based on Quality (31/100), Value (34/100), and Momentum (19/100) factor scores. The current signal is STRONG SELL.

Lexeo Therapeutics, Inc. is a clinical-stage gene therapy company focused on developing therapies for genetically defined cardiovascular, CNS, and other rare diseases. It utilizes a proprietary AAV gene therapy platform to target specific genetic defects, aiming to deliver one-time corrective treatments. The company is a specialized biotech company innovating in the gene therapy space, focusing on precision medicine for serious and often debilitating conditions.

Key Financial Metrics

Price$2.70
Market Cap$230M
P/E (Forward)-2.05
Price/Book0.94
Return on Equity-46.8%
Return on Invested Capital-34.6%
Debt/Equity0.03x
Operating Margin0.0%
Free Cash Flow$-99M

Lexeo Therapeutics, Inc. operates in the Biotechnology industry, part of the Healthcare sector (United States).

Frequently Asked Questions

What is Lexeo Therapeutics, Inc.’s (LXEO) StockRank?
MoatMap’s StockRank for Lexeo Therapeutics, Inc. (LXEO) is 10/100, with a Strong Sell signal. It is a composite of Quality (31), Value (34), and Momentum (19), each scored against its sector. The composite is then ranked across MoatMap’s universe of 24,000+ stocks.
Does Lexeo Therapeutics, Inc. have an economic moat?
Lexeo Therapeutics, Inc. (LXEO) has a Quality factor score of 31/100. The Quality factor combines ROIC, Piotroski F-Score, and leverage: the financial fingerprints of a durable competitive advantage. A Quality score above 70 typically indicates a company with the characteristics of a moated business.
Is Lexeo Therapeutics, Inc. a buy, hold, or sell?
MoatMap’s current signal for Lexeo Therapeutics, Inc. (LXEO) is Strong Sell, based on a StockRank of 10/100. Signals are derived mechanically from the StockRank composite and should be one input among many; combine with your own thesis on management, competitive position, and valuation.
What sector is Lexeo Therapeutics, Inc. in?
Lexeo Therapeutics, Inc. (LXEO) operates in the Healthcare sector, specifically the Biotechnology industry (United States).