LYEL

Strong SellSinker

Lyell Immunopharma, Inc. · Healthcare · United States · $230M cap · $1.6M/day traded

$9.31 -0.9% · close 26 Oct · scored 27 Oct

Sinker: Weak, expensive and falling. Nothing here to keep it afloat.

7
StockRank
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Quality
18
Value
32
Momentum
27

As of 27 Oct 2026, MoatMap's StockRank for Lyell Immunopharma, Inc. (LYEL) is 7/100, ranked against 24,000+ stocks in 35 markets (Quality 18, Value 32, Momentum 27, each scored against its sector).

Does StockRank work? Each month we publish how every decile did, whichever way it went. See the record →

P/E (TTM)
—
peers 27.2x
ROE
-93.3%
peers -30.1%
D/E
0.2x
peers 0.2x
Dividend %
—
trailing yield

ABOUT LYELL IMMUNOPHARMA, INC.

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Lyell Immunopharma, Inc. is a clinical-stage T-cell reprogramming company developing novel cell therapies for cancer. It focuses on overcoming key challenges in cell therapy, such as T-cell exhaustion and poor trafficking, through innovative genetic and epigenetic reprogramming technologies. Lyell is a biotech innovator dedicated to enhancing the durability, potency, and localization of T-cells to improve cancer treatments.

FINANCIAL SUMMARY (USD)

Year2022202320242025CAGRTTM2026E2027EFwd CAGR
Revenue84.7M0.1M61.0K36.0K-92.5%27.0K11.9K9.9K-47.6%
EPS-14.80-18.70-23.26-12.91—-12.86-6.92-6.32—
Shares12.5M12.7M14.7M21.3M+70.3%24.5M———
Debt67.7M63.2M59.0M51.0M-9.0%46.6M———
Equity833.3M655.0M382.8M248.2M-33.2%————
Op CF-169.6M-163.7M-162.4M-150.0M—-133.3M———
Inv CF-11.5M184.0M122.4M54.1M—————
Fin CF10.6M1.7M1.3M50.4M—————
Loading 1Y...
PRICE (1Y) · USD-14.7%
7.58.49.310.211.115 Sep6 Oct26 Oct
SMA 50SMA 200

Price checkStill fallingExperimental

Made a new 52-week low 8 trading days ago, 79% below its 52-week high. The fall has not stopped yet.

SwingsVery bumpy

Swung more than 88% of stocks we rank over the past year (79% a year).

How this is worked out

StockRank judges the business. The price check reads only the chart: it is the price side of the Momentum score, in words.

The rules: Still falling is a new 52-week low in the last two weeks, at least 25% below the high. Finding a floor is no new low since. Turning up is 20 or more trading days without a new low, at least 10% off it, and back above a rising 50-day average. In an uptrend is above the 200-day average and within 15% of the high.

In 2,112 US drawdowns since 2001, buying while the price was still falling was followed by a further 20% drop 42% of the time. Waiting for a turn like this one cut that to 33%, at about 7% higher prices and with no better returns. Part of that cut is simply not buying: 13% of falls never turned, and waiting kept those out. Among turns that were bought, 38% still fell another 20%, and 33% of turns were followed by a new low within six months. The benefit was largest in crashes such as 2008 and 2020.

What it measures: day-to-day price moves over the past year, as a yearly figure, ranked against every stock we cover. Very calm under 20% a year, Calm 20 to 30%, Average 30 to 40%, Bumpy 40 to 55%, Very bumpy above that.

What we found: across about 13,500 stocks in 34 markets (2002 to 2025), past swings were a good guide to the next year's, and bumpier stocks fell further. How much further changed too much between eras to put a number on it.

Calm is not safe: a calm stock can still slide steadily.

Rules fixed before any data was fetched. Describes the chart, not a recommendation.

Close
$9.31
RSI (14)
58.1
52-Week Range-79.3% from high
Low $7.20High $45.00

SCORE BREAKDOWN

Quality
18
ROIC
-65.4%11.3
ROE
-93.3%10.0
GP/Assets
0.0%10.1
Op. Margin
-1183425.0%0.1
FCF/Assets
-39.4%10.9
Piotroski
12.3
Int. Cover
—N/A
D/E Ratio
0.20x50.2
Current Ratio
5.36x74.4
Value
32
P/E (TTM)
—N/A
EV/EBITDA
-0.4x25.0
P/FCF
—N/A
P/B
0.9x84.4
P/S
8522.3x0.6
Div Yield
—N/A
Momentum
27
52W High %
21%4.8
RS 6M
-66%4.6
SMA 50/200
0.66x6.1
EPS Rev 4W
0.0%51.1
EPS Rev 12W
+62.4%97.5
EPS Improve
+51%54.7
Q Growth
—N/A

FUNDAMENTALS

Market Cap
$230M
P/E (Forward)
-1.5x
Gross Margin
100.0%

SECTOR PEERS

Closest peers in Healthcare, ranked by industry match, size, and score similarity. Cross-listings of LYEL are excluded.

TickerCompanyMkt CapStockRankSignal
LYELLyell Immunopharma, Inc.(you)$230M7Strong Sell
GLSIGreenwich LifeSciences, Inc.$235M7Strong Sell
CAMPCAMP4 THERAPEUTICS CORPORATION$207M7Strong Sell
BBOTBridgeBio Oncology Therapeutics, Inc.$213M5Strong Sell
LXEOLexeo Therapeutics, Inc.$230M10Strong Sell
LCTXLineage Cell Therapeutics, Inc.$253M4Strong Sell
VOGXVogenx, Inc.$259M5Strong Sell
LRMRLarimar Therapeutics, Inc.$244M10Strong Sell
ZNTLZentalis Pharmaceuticals, Inc.$217M10Strong Sell
PYXSPyxis Oncology, Inc.$201M9Strong Sell

Peer medians: ROE -30.1% · P/E 27.2x · Gross margin 63.3%

Company Deep Dive

Business segments breakdown, earnings transcript analysis, management credibility scoring, competitive landscape, and scenario modelling.

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Lyell Immunopharma, Inc. (LYEL): Stock Score Summary

Lyell Immunopharma, Inc. (LYEL) has a MoatMap StockRank of 7/100 based on Quality (18/100), Value (32/100), and Momentum (27/100) factor scores. The current signal is STRONG SELL.

Lyell Immunopharma, Inc. is a clinical-stage T-cell reprogramming company developing novel cell therapies for cancer. It focuses on overcoming key challenges in cell therapy, such as T-cell exhaustion and poor trafficking, through innovative genetic and epigenetic reprogramming technologies. Lyell is a biotech innovator dedicated to enhancing the durability, potency, and localization of T-cells to improve cancer treatments.

Key Financial Metrics

Price$9.31
Market Cap$230M
P/E (Forward)-1.49
Price/Book0.94
Return on Equity-93.3%
Return on Invested Capital-65.4%
Debt/Equity0.20x
Gross Margin100.0%
Operating Margin-1183425.0%
Revenue Growth-50.0%
Free Cash Flow$-134M

Lyell Immunopharma, Inc. operates in the Biotechnology industry, part of the Healthcare sector (United States).

Frequently Asked Questions

What is Lyell Immunopharma, Inc.’s (LYEL) StockRank?
MoatMap’s StockRank for Lyell Immunopharma, Inc. (LYEL) is 7/100, with a Strong Sell signal. It is a composite of Quality (18), Value (32), and Momentum (27), each scored against its sector. The composite is then ranked across MoatMap’s universe of 24,000+ stocks.
Does Lyell Immunopharma, Inc. have an economic moat?
Lyell Immunopharma, Inc. (LYEL) has a Quality factor score of 18/100. The Quality factor combines ROIC, Piotroski F-Score, and leverage: the financial fingerprints of a durable competitive advantage. A Quality score above 70 typically indicates a company with the characteristics of a moated business.
Is Lyell Immunopharma, Inc. a buy, hold, or sell?
MoatMap’s current signal for Lyell Immunopharma, Inc. (LYEL) is Strong Sell, based on a StockRank of 7/100. Signals are derived mechanically from the StockRank composite and should be one input among many; combine with your own thesis on management, competitive position, and valuation.
What sector is Lyell Immunopharma, Inc. in?
Lyell Immunopharma, Inc. (LYEL) operates in the Healthcare sector, specifically the Biotechnology industry (United States).