MAZE

Strong SellSinker

Maze Therapeutics, Inc. · Healthcare · United States · $1.7B cap · $28.7M/day traded

$31.07 +0.2% · close 26 Oct · scored 27 Oct

StockRank up 1.3 since 24 Oct.

Sinker: Weak, expensive and falling. Nothing here to keep it afloat.

13
StockRank
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Quality
27
Value
25
Momentum
37

As of 27 Oct 2026, MoatMap's StockRank for Maze Therapeutics, Inc. (MAZE) is 13/100, ranked against 24,000+ stocks in 35 markets (Quality 27, Value 25, Momentum 37, each scored against its sector).

Does StockRank work? Each month we publish how every decile did, whichever way it went. See the record →

P/E (TTM)
—
peers 27.2x
ROE
-37.3%
peers -30.1%
D/E
0.1x
peers 0.2x
Dividend %
—
trailing yield

ABOUT MAZE THERAPEUTICS, INC.

Read

Maze Therapeutics, Inc. is a clinical-stage biopharmaceutical company leveraging its proprietary "human genetic discovery engine" to identify and validate novel drug targets for common diseases. By integrating human genetics and functional genomics, the company aims to develop precision medicines that modulate disease-modifying genes. Its competitive advantage lies in its unique platform for identifying genetically-driven therapeutic opportunities and its focus on developing highly targeted treatments for underserved patient populations.

FINANCIAL SUMMARY (USD)

Year2022202320242025CAGRTTM2026E2027EFwd CAGR
Revenue00167.5M0——20.0M7.5M-64.5%
EPS-3.29-2.870.08-3.05—-2.48-2.73-3.19—
Shares43.8M43.8M43.8M49.3M+12.7%55.5M———
Debt32.1M49.6M26.6M23.3M-10.1%60.4M———
Equity-282.5M-373.8M-311.2M355.0M—————
Op CF-99.2M-86.8M76.0M-111.9M—-106.5M———
Inv CF-3.2M-0.4M-1.1M-171.0M—————
Fin CF1.7M16.4M92.8M275.3M—————
Loading 1Y...
PRICE (1Y) · USD+28.2%
22.424.927.530.032.615 Sep6 Oct26 Oct
SMA 50SMA 200

Price checkTurning upExperimental

41% above its 52-week low and back above a rising 50-day average since 22 Oct 2026.

The Momentum score still reads 37: it weighs six months of price and earnings revisions, so it trails a turn like this.

SwingsVery bumpy

Swung more than 81% of stocks we rank over the past year (68% a year).

How this is worked out

StockRank judges the business. The price check reads only the chart: it is the price side of the Momentum score, in words.

The rules: Still falling is a new 52-week low in the last two weeks, at least 25% below the high. Finding a floor is no new low since. Turning up is 20 or more trading days without a new low, at least 10% off it, and back above a rising 50-day average. In an uptrend is above the 200-day average and within 15% of the high.

In 2,112 US drawdowns since 2001, buying while the price was still falling was followed by a further 20% drop 42% of the time. Waiting for a turn like this one cut that to 33%, at about 7% higher prices and with no better returns. Part of that cut is simply not buying: 13% of falls never turned, and waiting kept those out. Among turns that were bought, 38% still fell another 20%, and 33% of turns were followed by a new low within six months. The benefit was largest in crashes such as 2008 and 2020.

What it measures: day-to-day price moves over the past year, as a yearly figure, ranked against every stock we cover. Very calm under 20% a year, Calm 20 to 30%, Average 30 to 40%, Bumpy 40 to 55%, Very bumpy above that.

What we found: across about 13,500 stocks in 34 markets (2002 to 2025), past swings were a good guide to the next year's, and bumpier stocks fell further. How much further changed too much between eras to put a number on it.

Calm is not safe: a calm stock can still slide steadily.

Rules fixed before any data was fetched. Describes the chart, not a recommendation.

Close
$31.07
RSI (14)
69.6
52-Week Range-42.1% from high
Low $21.95High $53.65

SCORE BREAKDOWN

Quality
27
ROIC
-34.9%21.5
ROE
-37.3%22.4
GP/Assets
5.0%18.5
Op. Margin
-728.1%8.4
FCF/Assets
-30.8%14.6
Piotroski
321.4
Int. Cover
—N/A
D/E Ratio
0.13x58.3
Current Ratio
18.31x95.0
Value
25
P/E (TTM)
—N/A
EV/EBITDA
-9.5x25.0
P/FCF
—N/A
P/B
3.8x33.8
P/S
86.1x6.6
Div Yield
—N/A
Momentum
37
52W High %
58%37.5
RS 6M
11%73.5
SMA 50/200
0.85x22.0
EPS Rev 4W
-0.4%17.3
EPS Rev 12W
+0.0%48.0
EPS Improve
-29%12.7
Q Growth
—N/A

FUNDAMENTALS

Market Cap
$1.7B
P/E (Forward)
-9.7x
Gross Margin
100.0%

SECTOR PEERS

Closest peers in Healthcare, ranked by industry match, size, and score similarity. Cross-listings of MAZE are excluded.

TickerCompanyMkt CapStockRankSignal
MAZEMaze Therapeutics, Inc.(you)$1.7B13Strong Sell
PVLAPalvella Therapeutics, Inc.$1.8B14Strong Sell
ZBIOZenas BioPharma, Inc.$1.8B15Strong Sell
MLYSMineralys Therapeutics, Inc.$1.8B14Strong Sell
KLRAKailera Therapeutics, Inc.$1.7B15Strong Sell
COAGHemab Therapeutics Holdings, Inc.$1.6B15Strong Sell
NTLAIntellia Therapeutics, Inc.$1.6B11Strong Sell
GPCRStructure Therapeutics Inc.$1.5B15Strong Sell
RAREUltragenyx Pharmaceutical Inc.$1.5B11Strong Sell
TYRATyra Biosciences, Inc.$1.4B12Strong Sell

Peer medians: ROE -30.1% · P/E 27.2x · Gross margin 63.3%

Company Deep Dive

Business segments breakdown, earnings transcript analysis, management credibility scoring, competitive landscape, and scenario modelling.

Request Deep Dive(50 Feathers)

Maze Therapeutics, Inc. (MAZE): Stock Score Summary

Maze Therapeutics, Inc. (MAZE) has a MoatMap StockRank of 13/100 based on Quality (27/100), Value (25/100), and Momentum (37/100) factor scores. The current signal is STRONG SELL.

Maze Therapeutics, Inc. is a clinical-stage biopharmaceutical company leveraging its proprietary "human genetic discovery engine" to identify and validate novel drug targets for common diseases. By integrating human genetics and functional genomics, the company aims to develop precision medicines that modulate disease-modifying genes. Its competitive advantage lies in its unique platform for identifying genetically-driven therapeutic opportunities and its focus on developing highly targeted treatments for underserved patient populations.

Key Financial Metrics

Price$31.07
Market Cap$1.7B
P/E (Forward)-9.73
Price/Book3.80
Return on Equity-37.3%
Return on Invested Capital-34.9%
Debt/Equity0.13x
Gross Margin100.0%
Operating Margin-728.1%
Free Cash Flow$-122M

Maze Therapeutics, Inc. operates in the Biotechnology industry, part of the Healthcare sector (United States).

Frequently Asked Questions

What is Maze Therapeutics, Inc.’s (MAZE) StockRank?
MoatMap’s StockRank for Maze Therapeutics, Inc. (MAZE) is 13/100, with a Strong Sell signal. It is a composite of Quality (27), Value (25), and Momentum (37), each scored against its sector. The composite is then ranked across MoatMap’s universe of 24,000+ stocks.
Does Maze Therapeutics, Inc. have an economic moat?
Maze Therapeutics, Inc. (MAZE) has a Quality factor score of 27/100. The Quality factor combines ROIC, Piotroski F-Score, and leverage: the financial fingerprints of a durable competitive advantage. A Quality score above 70 typically indicates a company with the characteristics of a moated business.
Is Maze Therapeutics, Inc. a buy, hold, or sell?
MoatMap’s current signal for Maze Therapeutics, Inc. (MAZE) is Strong Sell, based on a StockRank of 13/100. Signals are derived mechanically from the StockRank composite and should be one input among many; combine with your own thesis on management, competitive position, and valuation.
What sector is Maze Therapeutics, Inc. in?
Maze Therapeutics, Inc. (MAZE) operates in the Healthcare sector, specifically the Biotechnology industry (United States).