RARE

Strong SellSinker

Ultragenyx Pharmaceutical Inc. · Healthcare · United States · $1.5B cap · $75.9M/day traded

$16.08 +2.7% · close 26 Oct · scored 27 Oct

Sinker: Weak, expensive and falling. Nothing here to keep it afloat.

11
StockRank
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Report expected 3 Nov: the next-year EPS estimate has fallen 85.4% over the last 14 weeks.

Quality
22
Value
29
Momentum
33

As of 27 Oct 2026, MoatMap's StockRank for Ultragenyx Pharmaceutical Inc. (RARE) is 11/100, ranked against 24,000+ stocks in 35 markets (Quality 22, Value 29, Momentum 33, each scored against its sector).

Does StockRank work? Each month we publish how every decile did, whichever way it went. See the record →

P/E (TTM)
—
peers 27.2x
ROE
—
peers -30.2%
D/E
—
peers 0.2x
Dividend %
—
trailing yield

ABOUT ULTRAGENYX PHARMACEUTICAL INC.

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Ultragenyx Pharmaceutical Inc. is a biopharmaceutical company dedicated to developing and commercializing novel therapies for rare and ultra-rare genetic diseases. The company boasts a diversified pipeline spanning multiple therapeutic areas, with approved products addressing diseases like XLH and GNE myopathy. Ultragenyx's focus on orphan diseases and its integrated approach from research to commercialization gives it a strong competitive position in this high-barrier-to-entry market segment.

FINANCIAL SUMMARY (USD)

Year2022202320242025CAGRTTM2026E2027EFwd CAGR
Revenue363.3M434.0M560.0M673.0M22.8%717.0M760.2M997.0M21.7%
EPS-10.12-8.25-6.29-5.83—-5.82-4.080.23—
Shares70.2M82.3M92.5M96.5M+37.4%98.6M———
Debt31.6M43.2M40.0M36.0M4.4%————
Equity352.5M275.4M255.0M-80.0M-14.9%————
Op CF-380.5M-475.0M-414.0M-466.0M—-485.0M———
Inv CF-291.7M168.0M-18.0M236.0M—————
Fin CF501.2M388.0M399.0M478.0M—————
Loading 1Y...
PRICE (1Y) · USD+23.0%
12.913.714.515.316.115 Sep6 Oct26 Oct
SMA 50SMA 200

Price checkFinding a floorExperimental

No new 52-week low for 5 weeks, 26% above that low, but not back above a rising 50-day average.

SwingsVery bumpy

Swung more than 89% of stocks we rank over the past year (82% a year).

How this is worked out

StockRank judges the business. The price check reads only the chart: it is the price side of the Momentum score, in words.

The rules: Still falling is a new 52-week low in the last two weeks, at least 25% below the high. Finding a floor is no new low since. Turning up is 20 or more trading days without a new low, at least 10% off it, and back above a rising 50-day average. In an uptrend is above the 200-day average and within 15% of the high.

In 2,112 US drawdowns since 2001, buying while the price was still falling was followed by a further 20% drop 42% of the time. Waiting for a turn like this one cut that to 33%, at about 7% higher prices and with no better returns. Part of that cut is simply not buying: 13% of falls never turned, and waiting kept those out. Among turns that were bought, 38% still fell another 20%, and 33% of turns were followed by a new low within six months. The benefit was largest in crashes such as 2008 and 2020.

What it measures: day-to-day price moves over the past year, as a yearly figure, ranked against every stock we cover. Very calm under 20% a year, Calm 20 to 30%, Average 30 to 40%, Bumpy 40 to 55%, Very bumpy above that.

What we found: across about 13,500 stocks in 34 markets (2002 to 2025), past swings were a good guide to the next year's, and bumpier stocks fell further. How much further changed too much between eras to put a number on it.

Calm is not safe: a calm stock can still slide steadily.

Rules fixed before any data was fetched. Describes the chart, not a recommendation.

Close
$16.08
RSI (14)
66.7
52-Week Range-59.7% from high
Low $12.73High $39.89

SCORE BREAKDOWN

Quality
22
ROIC
-44.0%17.6
ROE
—N/A
GP/Assets
-9.7%6.0
Op. Margin
-35.0%22.0
FCF/Assets
-32.2%13.6
Piotroski
549.3
Int. Cover
-6.6x25.2
D/E Ratio
—N/A
Current Ratio
1.73x33.4
Value
29
P/E (TTM)
—N/A
EV/EBITDA
-5.3x25.0
P/FCF
—N/A
P/B
-5.3x25.0
P/S
2.2x64.2
Div Yield
—N/A
Momentum
33
52W High %
40%17.2
RS 6M
-40%17.5
SMA 50/200
0.77x12.7
EPS Rev 4W
+11.8%97.1
EPS Rev 12W
-85.5%0.2
EPS Improve
+104%74.9
Q Growth
—N/A

FUNDAMENTALS

Market Cap
$1.5B
P/E (Forward)
69.4x
Gross Margin
83.8%

SECTOR PEERS

Closest peers in Healthcare, ranked by industry match, size, and score similarity. Cross-listings of RARE are excluded.

TickerCompanyMkt CapStockRankSignal
RAREUltragenyx Pharmaceutical Inc.(you)$1.5B11Strong Sell
NTLAIntellia Therapeutics, Inc.$1.6B11Strong Sell
LYCALycia Therapeutics, Inc.$1.6B10Strong Sell
STOKStoke Therapeutics, Inc.$1.6B9Strong Sell
TYRATyra Biosciences, Inc.$1.4B12Strong Sell
GENBGenerate Biomedicines, Inc.$1.6B8Strong Sell
GPCRStructure Therapeutics Inc.$1.5B15Strong Sell
MAZEMaze Therapeutics, Inc.$1.7B13Strong Sell
COAGHemab Therapeutics Holdings, Inc.$1.6B15Strong Sell
OCULOcular Therapeutix, Inc.$1.4B7Strong Sell

Peer medians: ROE -30.2% · P/E 27.2x · Gross margin 63.3%

Company Deep Dive

Business segments breakdown, earnings transcript analysis, management credibility scoring, competitive landscape, and scenario modelling.

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Ultragenyx Pharmaceutical Inc. (RARE): Stock Score Summary

Ultragenyx Pharmaceutical Inc. (RARE) has a MoatMap StockRank of 11/100 based on Quality (22/100), Value (29/100), and Momentum (33/100) factor scores. The current signal is STRONG SELL.

Ultragenyx Pharmaceutical Inc. is a biopharmaceutical company dedicated to developing and commercializing novel therapies for rare and ultra-rare genetic diseases. The company boasts a diversified pipeline spanning multiple therapeutic areas, with approved products addressing diseases like XLH and GNE myopathy. Ultragenyx's focus on orphan diseases and its integrated approach from research to commercialization gives it a strong competitive position in this high-barrier-to-entry market segment.

Key Financial Metrics

Price$16.08
Market Cap$1.5B
P/E (Forward)69.37
Price/Book-5.29
Return on Invested Capital-44.0%
Gross Margin83.8%
Operating Margin-35.0%
Revenue Growth28.1%
Free Cash Flow$-494M

Ultragenyx Pharmaceutical Inc. operates in the Biotechnology industry, part of the Healthcare sector (United States).

Frequently Asked Questions

What is Ultragenyx Pharmaceutical Inc.’s (RARE) StockRank?
MoatMap’s StockRank for Ultragenyx Pharmaceutical Inc. (RARE) is 11/100, with a Strong Sell signal. It is a composite of Quality (22), Value (29), and Momentum (33), each scored against its sector. The composite is then ranked across MoatMap’s universe of 24,000+ stocks.
Does Ultragenyx Pharmaceutical Inc. have an economic moat?
Ultragenyx Pharmaceutical Inc. (RARE) has a Quality factor score of 22/100. The Quality factor combines ROIC, Piotroski F-Score, and leverage: the financial fingerprints of a durable competitive advantage. A Quality score above 70 typically indicates a company with the characteristics of a moated business.
Is Ultragenyx Pharmaceutical Inc. a buy, hold, or sell?
MoatMap’s current signal for Ultragenyx Pharmaceutical Inc. (RARE) is Strong Sell, based on a StockRank of 11/100. Signals are derived mechanically from the StockRank composite and should be one input among many; combine with your own thesis on management, competitive position, and valuation.
What sector is Ultragenyx Pharmaceutical Inc. in?
Ultragenyx Pharmaceutical Inc. (RARE) operates in the Healthcare sector, specifically the Biotechnology industry (United States).