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UPB

Strong SellSinker

Upstream Bio, Inc. · Healthcare · United States · $366M · Avg Vol: $4M/d

8
StockRank
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Q
28
V
32
M
18
P/E (TTM)
ROE
-46.1%
D/E
0.0x
Dividend %

COMPANY DESCRIPTION

Upstream Bio, Inc. is a biotechnology company focused on discovering and developing novel therapeutics for inflammatory and immunological diseases. The company's competitive moat is built upon its proprietary drug candidates, designed to target specific pathways involved in various immune-mediated conditions, addressing critical unmet needs in these therapeutic areas. Upstream Bio is an emerging biopharmaceutical firm committed to advancing immunology research.

FINANCIAL SUMMARY (USD)

Year2022202320242025CAGRTTM2026E2027EFwd CAGR
Revenue1.2M2.4M2.4M2.9M33.0%3.2M2.7M1.7M-23.6%
EPS-0.66-1.05-1.17-2.64-2.88-2.90-2.93
Shares51.3M51.3M53.6M54.2M+5.6%54.8M
Debt94.0K45.0K1.8M1.3M138.1%1.0M
Equity-106.2M-123.1M469.9M339.8M-27.7%
Op CF-19.0M-37.9M-59.2M-133.3M-136.3M
Inv CF-82.0K-82.8M-59.5M-93.5M
Fin CF10.0M129.6M418.9M2.4M
Loading 1Y...
PRICE (1Y)-12.5%
5.756.196.637.077.51Jul 30Aug 20Sep 10
SMA 50SMA 200

Close
$5.75
RSI (14)
30.6
52W High
$33.68
From 52W High
0.2%

SCORE BREAKDOWN

Quality
28
ROIC
-50.5%15.7
ROE
-46.1%19.7
GP/Assets
0.9%12.4
Op. Margin
-5481.0%3.4
FCF/Assets
-37.7%10.1
Piotroski
321.9
Int. Cover
N/A
D/E Ratio
0.00x90.3
Current Ratio
27.99x97.8
Value
32
P/E (TTM)
N/A
EV/EBITDA
-0.4x25.0
P/FCF
N/A
P/B
1.1x83.8
P/S
104.2x6.8
Div Yield
N/A
Momentum
18
52W High %
17%2.7
RS 6M
-51%12.3
SMA 50/200
0.51x2.2
EPS Rev 4W
-1.5%23.5
EPS Rev 12W
+3.2%74.9
EPS Improve
-2%21.8
Q Growth
N/A

FUNDAMENTALS

Market Cap
$366M
P/E (Forward)
-2.1x
Gross Margin
100.0%

SECTOR PEERS

Closest peers in Healthcare, ranked by industry match, size, and score similarity. Cross-listings of UPB are excluded.

TickerCompanyMkt CapStockRankSignal
UPBUpstream Bio, Inc.(you)$366M8Strong Sell
LYELLyell Immunopharma, Inc.$356M7Strong Sell
FHTXFoghorn Therapeutics Inc.$356M7Strong Sell
LXEOLexeo Therapeutics, Inc.$399M7Strong Sell
STROSutro Biopharma, Inc.$339M9Strong Sell
EVMNEvommune, Inc.$480M8Strong Sell
GALTGalectin Therapeutics Inc.$405M11Strong Sell
RCKTRocket Pharmaceuticals, Inc.$424M10Strong Sell
CMPXCompass Therapeutics, Inc.$432M5Strong Sell
EYPTEyePoint, Inc.$376M2Strong Sell

Peer medians: ROE -30.2% · P/E 27.0x · Gross margin 58.1%

Upstream Bio, Inc. (UPB): Stock Score Summary

Upstream Bio, Inc. (UPB) has a MoatMap StockRank of 8/100 based on Quality (28/100), Value (32/100), and Momentum (18/100) factor scores. The current signal is STRONG SELL.

Upstream Bio, Inc. is a biotechnology company focused on discovering and developing novel therapeutics for inflammatory and immunological diseases. The company's competitive moat is built upon its proprietary drug candidates, designed to target specific pathways involved in various immune-mediated conditions, addressing critical unmet needs in these therapeutic areas. Upstream Bio is an emerging biopharmaceutical firm committed to advancing immunology research.

Key Financial Metrics

Price$5.75
Market Cap$366M
P/E (Forward)-2.05
Price/Book1.08
Return on Equity-46.1%
Return on Invested Capital-50.5%
Debt/Equity0.00x
Gross Margin100.0%
Operating Margin-5481.0%
Revenue Growth-17.5%
Free Cash Flow$-133M

Upstream Bio, Inc. operates in the Biotechnology industry, part of the Healthcare sector (United States).

Frequently Asked Questions

What is Upstream Bio, Inc.’s (UPB) StockRank?
MoatMap’s StockRank for Upstream Bio, Inc. (UPB) is 8/100, with a Strong Sell signal. It is a composite of Quality (28), Value (32), and Momentum (18) factor ranks across MoatMap’s universe of 25,000+ stocks.
Does Upstream Bio, Inc. have an economic moat?
Upstream Bio, Inc. (UPB) has a Quality factor score of 28/100. The Quality factor combines ROIC, Piotroski F-Score, and leverage: the financial fingerprints of a durable competitive advantage. A Quality score above 70 typically indicates a company with the characteristics of a moated business.
Is Upstream Bio, Inc. a buy, hold, or sell?
MoatMap’s current signal for Upstream Bio, Inc. (UPB) is Strong Sell, based on a StockRank of 8/100. Signals are derived mechanically from the StockRank composite and should be one input among many; combine with your own thesis on management, competitive position, and valuation.
What sector is Upstream Bio, Inc. in?
Upstream Bio, Inc. (UPB) operates in the Healthcare sector, specifically the Biotechnology industry (United States).