HALO

Strong BuyPremium GrowerAI neutral

Halozyme Therapeutics, Inc. · Healthcare · United States · $14.3B cap · $328.9M/day traded

$125.63 +0.9% · close 23 Oct · scored 24 Oct

Premium Grower: Strong business with the market behind it, priced at a premium.

Read our full research report on HALO (Jun 2026), free
94
StockRank
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Report expected 2 Nov: the next-year EPS estimate has risen 7.7% over the last 14 weeks.

Quality
77
Value
33
Momentum
91

As of 24 Oct 2026, MoatMap's StockRank for Halozyme Therapeutics, Inc. (HALO) is 94/100, ranked against 24,000+ stocks in 35 markets (Quality 77, Value 33, Momentum 91, each scored against its sector).

Does StockRank work? Each month we publish how every decile did, whichever way it went. See the record →

P/E (TTM)
36.7x
peers 27.3x
ROE
173.7%
peers -31.5%
D/E
15.2x
peers 0.2x
Dividend %
—
trailing yield
AI CONVICTION THESIS

Halozyme earns high-margin royalties from its ENHANZE drug-delivery technology, which lets partners such as Roche, J&J and Bristol Myers convert intravenous drugs to subcutaneous injections. This asset-light model produces high returns on capital. The company recently raised full-year guidance, has an active buyback and is broadening into other drug-delivery platforms. It just priced an upsized $1.3 billion convertible note offering due 2033, adding leverage and potential dilution. The main uncertainty is how durable ENHANZE royalties are as key patents approach expiry later this decade.

ABOUT HALOZYME THERAPEUTICS, INC.

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Halozyme Therapeutics, Inc. is a biotechnology company focused on its proprietary ENHANZE® drug delivery technology, utilizing recombinant human hyaluronidase enzyme (rHuPH20). This innovative platform facilitates subcutaneous administration of biologics, thereby improving patient convenience and reducing healthcare costs. Halozyme operates primarily through a high-margin licensing model, partnering with major pharmaceutical companies to enhance the delivery of their blockbuster therapeutics.

FINANCIAL SUMMARY (USD)

Year2022202320242025CAGRTTM2026E2027EFwd CAGR
Revenue660.1M829.3M1.0B1.4B28.4%1.7B1.9B2.1B22.6%
EPS1.482.133.502.6421.3%3.42———
Shares135.2M126.8M123.1M117.8M-12.9%113.5M———
Debt1.5B1.5B1.5B2.1B12.5%2.2B———
Equity169.8M83.8M363.8M48.8M-34.0%————
Op CF240.1M388.6M479.1M651.6M39.5%818.6M———
Inv CF-487.0M-96.9M-262.7M-545.8M—————
Fin CF362.4M-408.0M-218.9M-85.2M—————
Loading 1Y...
PRICE (1Y) · USD+16.4%
10611111612112614 Sep5 Oct23 Oct
SMA 50SMA 200

Price checkIn an uptrendExperimental

Above its 200-day average and at its 52-week high.

SwingsAverage

Calmer than 58% of stocks we rank over the past year (37% a year).

How this is worked out

StockRank judges the business. The price check reads only the chart: it is the price side of the Momentum score, in words.

The rules: Still falling is a new 52-week low in the last two weeks, at least 25% below the high. Finding a floor is no new low since. Turning up is 20 or more trading days without a new low, at least 10% off it, and back above a rising 50-day average. In an uptrend is above the 200-day average and within 15% of the high.

In 2,112 US drawdowns since 2001, buying while the price was still falling was followed by a further 20% drop 42% of the time. Waiting for a turn like this one cut that to 33%, at about 7% higher prices and with no better returns. Part of that cut is simply not buying: 13% of falls never turned, and waiting kept those out. Among turns that were bought, 38% still fell another 20%, and 33% of turns were followed by a new low within six months. The benefit was largest in crashes such as 2008 and 2020.

What it measures: day-to-day price moves over the past year, as a yearly figure, ranked against every stock we cover. Very calm under 20% a year, Calm 20 to 30%, Average 30 to 40%, Bumpy 40 to 55%, Very bumpy above that.

What we found: across about 13,500 stocks in 34 markets (2002 to 2025), past swings were a good guide to the next year's, and bumpier stocks fell further. How much further changed too much between eras to put a number on it.

Calm is not safe: a calm stock can still slide steadily.

Rules fixed before any data was fetched. Describes the chart, not a recommendation.

Close
$125.63
RSI (14)
88.1
52-Week Range-0.5% from high
Low $61.23High $126.23

SCORE BREAKDOWN

Quality
77
ROIC
25.7%94.4
ROE
173.7%99.8
GP/Assets
50.2%87.4
Op. Margin
59.8%99.0
FCF/Assets
20.5%96.6
Piotroski
549.0
Int. Cover
29.7x75.2
D/E Ratio
15.18x0.7
Current Ratio
2.71x51.9
Value
33
P/E (TTM)
36.7x32.2
EV/EBITDA
15.4x46.5
P/FCF
27.5x45.6
P/B
99.8x0.6
P/S
8.6x27.5
Div Yield
—N/A
Momentum
91
52W High %
100%99.1
RS 6M
85%96.2
SMA 50/200
1.36x95.5
EPS Rev 4W
+2.8%93.5
EPS Rev 12W
+7.8%83.4
EPS Improve
+212%88.2
Q Growth
39%69.9

FUNDAMENTALS

Market Cap
$14.3B
P/E (Forward)
11.8x
Gross Margin
76.3%

SECTOR PEERS

Closest peers in Healthcare, ranked by industry match, size, and score similarity. Cross-listings of HALO are excluded.

TickerCompanyMkt CapStockRankSignal
HALOHalozyme Therapeutics, Inc.(you)$14.3B94Strong Buy
EXELExelixis, Inc.$16.0B98Strong Buy
INCYIncyte Corporation$23.5B94Strong Buy
TECHBio-Techne Corporation$11.4B73Buy
NRIXNurix Therapeutics, Inc.$2.8B95Strong Buy
CORTCorcept Therapeutics Incorporated$9.3B67Buy
CAICaris Life Sciences, Inc.$9.0B68Buy
KRYSKrystal Biotech, Inc.$9.2B67Buy
PTGXProtagonist Therapeutics, Inc.$9.0B66Buy
LGNDLigand Pharmaceuticals Incorporated$6.1B71Buy

Peer medians: ROE -31.5% · P/E 27.3x · Gross margin 62.6%

Company Deep Dive

Read the full research report: business segments breakdown, earnings transcripts review, management credibility analysis, competitive landscape, and scenarios.

View Deep Dive

Halozyme Therapeutics, Inc. (HALO): Stock Score Summary

Halozyme Therapeutics, Inc. (HALO) has a MoatMap StockRank of 94/100 based on Quality (77/100), Value (33/100), and Momentum (91/100) factor scores. The current signal is STRONG BUY. Halozyme earns high-margin royalties from its ENHANZE drug-delivery technology, which lets partners such as Roche, J&J and Bristol Myers convert intravenous drugs to subcutaneous injections. This asset-light model produces high returns on capital. The company recently raised full-year guidance, has an active buyback and is broadening into other drug-delivery platforms. It just priced an upsized $1.3 billion convertible note offering due 2033, adding leverage and potential dilution. The main uncertainty is how durable ENHANZE royalties are as key patents approach expiry later this decade.

Halozyme Therapeutics, Inc. is a biotechnology company focused on its proprietary ENHANZE® drug delivery technology, utilizing recombinant human hyaluronidase enzyme (rHuPH20). This innovative platform facilitates subcutaneous administration of biologics, thereby improving patient convenience and reducing healthcare costs. Halozyme operates primarily through a high-margin licensing model, partnering with major pharmaceutical companies to enhance the delivery of their blockbuster therapeutics.

Key Financial Metrics

Price$125.63
Market Cap$14.3B
P/E (TTM)36.73
P/E (Forward)11.76
Price/Book99.79
Return on Equity173.7%
Return on Invested Capital25.7%
Debt/Equity15.18x
Gross Margin76.3%
Operating Margin59.8%
Revenue Growth47.7%
Free Cash Flow$518M

Halozyme Therapeutics, Inc. operates in the Biotechnology industry, part of the Healthcare sector (United States).

Frequently Asked Questions

What is Halozyme Therapeutics, Inc.’s (HALO) StockRank?
MoatMap’s StockRank for Halozyme Therapeutics, Inc. (HALO) is 94/100, with a Strong Buy signal. It is a composite of Quality (77), Value (33), and Momentum (91), each scored against its sector. The composite is then ranked across MoatMap’s universe of 24,000+ stocks.
Does Halozyme Therapeutics, Inc. have an economic moat?
Halozyme Therapeutics, Inc. (HALO) has a Quality factor score of 77/100. The Quality factor combines ROIC, Piotroski F-Score, and leverage: the financial fingerprints of a durable competitive advantage. A Quality score above 70 typically indicates a company with the characteristics of a moated business.
Is Halozyme Therapeutics, Inc. a buy, hold, or sell?
MoatMap’s current signal for Halozyme Therapeutics, Inc. (HALO) is Strong Buy, based on a StockRank of 94/100. Signals are derived mechanically from the StockRank composite and should be one input among many; combine with your own thesis on management, competitive position, and valuation.
What sector is Halozyme Therapeutics, Inc. in?
Halozyme Therapeutics, Inc. (HALO) operates in the Healthcare sector, specifically the Biotechnology industry (United States).