EXEL

Strong BuyPremium GrowerAI neutral

Exelixis, Inc. · Healthcare · United States · $14.1B cap · $134.8M/day traded

$59.82 -0.1% · close 12 Oct · scored 14 Oct

Premium Grower: Strong business with the market behind it, priced at a premium.

Read our full research report on EXEL (Jun 2026), free
98
StockRank
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Report expected 27 Oct: the next-year EPS estimate has risen 7.1% over the last 13 weeks.

Quality
89
Value
49
Momentum
76

As of 14 Oct 2026, MoatMap's StockRank for Exelixis, Inc. (EXEL) is 98/100, ranked against 24,000+ stocks in 35 markets (Quality 89, Value 49, Momentum 76, each scored against its sector).

Does StockRank work? Each month we publish how every decile did, whichever way it went. See the record →

P/E (TTM)
18.9x
peers 29.0x
ROE
44.4%
peers -26.1%
D/E
0.1x
peers 0.2x
Dividend %
—
trailing yield
AI screening note

Exelixis generates strong free cash flow underpinned by its flagship cabozantinib franchise and executes regular share repurchases. However, recent director share sales create an offsetting signal that warrants a measured stance while monitoring pipeline diversification progress.

ABOUT EXELIXIS, INC.

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Exelixis, Inc. is a biotechnology company focused on the discovery, development, and commercialization of innovative small molecule therapies for cancer. Its competitive strength stems from its flagship oncology product, CABOMETYX, and a robust pipeline targeting various cancer indications, establishing it as a significant player in the oncology therapeutics market.

FINANCIAL SUMMARY (USD)

Year2022202320242025CAGRTTM2026E2027EFwd CAGR
Revenue1.6B1.8B2.2B2.3B12.9%2.4B2.6B2.9B11.8%
EPS0.560.651.802.8872.6%3.173.354.0017.8%
Shares324.0M302.8M281.7M262.5M-19.0%247.8M———
Debt190.2M189.9M190.8M173.0M-3.1%165.9M———
Equity2.5B2.3B2.2B2.2B-4.6%————
Op CF362.6M333.3M700.0M884.3M34.6%1.2B———
Inv CF-524.4M-27.0M-116.8M350.4M—————
Fin CF0.6M-546.1M-628.8M-969.6M—————
Loading 1Y...
PRICE (1Y) · USD+9.5%
54.655.957.358.659.931 Aug22 Sep12 Oct
SMA 50SMA 200

Price checkIn an uptrendExperimental

Above its 200-day average and 3% below its 52-week high.

SwingsAverage

Calmer than 59% of stocks we rank over the past year (37% a year).

How this is worked out

StockRank judges the business. The price check reads only the chart: it is the price side of the Momentum score, in words.

The rules: Still falling is a new 52-week low in the last two weeks, at least 25% below the high. Finding a floor is no new low since. Turning up is 20 or more trading days without a new low, at least 10% off it, and back above a rising 50-day average. In an uptrend is above the 200-day average and within 15% of the high.

In 2,112 US drawdowns since 2001, buying while the price was still falling was followed by a further 20% drop 42% of the time. Waiting for a turn like this one cut that to 33%, at about 7% higher prices and with no better returns. Part of that cut is simply not buying: 13% of falls never turned, and waiting kept those out. Among turns that were bought, 38% still fell another 20%, and 33% of turns were followed by a new low within six months. The benefit was largest in crashes such as 2008 and 2020.

What it measures: day-to-day price moves over the past year, as a yearly figure, ranked against every stock we cover. Very calm under 20% a year, Calm 20 to 30%, Average 30 to 40%, Bumpy 40 to 55%, Very bumpy above that.

What we found: across about 13,500 stocks in 34 markets (2002 to 2025), past swings were a good guide to the next year's, and bumpier stocks fell further. How much further changed too much between eras to put a number on it.

Calm is not safe: a calm stock can still slide steadily.

Rules fixed before any data was fetched. Describes the chart, not a recommendation.

Close
$59.82
RSI (14)
61.8
52-Week Range-3.0% from high
Low $33.76High $61.66

SCORE BREAKDOWN

Quality
89
ROIC (ROA)
24.0%*93.3
ROE
44.4%96.8
GP/Assets
82.6%97.0
Op. Margin
39.5%96.4
FCF/Assets
40.7%99.1
Piotroski
783.5
Int. Cover
50.0x89.4
D/E Ratio
0.09x64.1
Current Ratio
3.46x61.4
Value
49
P/E (TTM)
18.9x63.2
EV/EBITDA
13.9x51.3
P/FCF
12.1x75.3
P/B
8.1x14.4
P/S
6.1x36.3
Div Yield
—N/A
Momentum
76
52W High %
97%96.2
RS 6M
19%81.2
SMA 50/200
1.14x82.0
EPS Rev 4W
+0.3%76.0
EPS Rev 12W
+7.1%82.1
EPS Improve
+35%44.0
Q Growth
15%50.8

FUNDAMENTALS

Market Cap
$14.1B
P/E (Forward)
14.0x
Gross Margin
96.5%

SECTOR PEERS

Closest peers in Healthcare, ranked by industry match, size, and score similarity. Cross-listings of EXEL are excluded.

TickerCompanyMkt CapStockRankSignal
EXELExelixis, Inc.(you)$14.1B98Strong Buy
HALOHalozyme Therapeutics, Inc.$12.8B95Strong Buy
INCYIncyte Corporation$25.3B93Strong Buy
CORTCorcept Therapeutics Incorporated$12.2B75Buy
TECHBio-Techne Corporation$11.4B73Buy
KRYSKrystal Biotech, Inc.$10.1B70Buy
BMRNBioMarin Pharmaceutical Inc.$12.0B65Buy
HRMYHarmony Biosciences Holdings, Inc.$2.4B100Strong Buy
CAICaris Life Sciences, Inc.$8.9B65Hold
LGNDLigand Pharmaceuticals Incorporated$5.9B73Buy

Peer medians: ROE -26.1% · P/E 29.0x · Gross margin 64.2%

Company Deep Dive

Read the full research report: business segments breakdown, earnings transcripts review, management credibility analysis, competitive landscape, and scenarios.

View Deep Dive

Exelixis, Inc. (EXEL): Stock Score Summary

Exelixis, Inc. (EXEL) has a MoatMap StockRank of 98/100 based on Quality (89/100), Value (49/100), and Momentum (76/100) factor scores. The current signal is STRONG BUY. Exelixis generates strong free cash flow underpinned by its flagship cabozantinib franchise and executes regular share repurchases. However, recent director share sales create an offsetting signal that warrants a measured stance while monitoring pipeline diversification progress.

Exelixis, Inc. is a biotechnology company focused on the discovery, development, and commercialization of innovative small molecule therapies for cancer. Its competitive strength stems from its flagship oncology product, CABOMETYX, and a robust pipeline targeting various cancer indications, establishing it as a significant player in the oncology therapeutics market.

Key Financial Metrics

Price$59.82
Market Cap$14.1B
P/E (TTM)18.88
P/E (Forward)14.01
Price/Book8.08
Return on Equity44.4%
Debt/Equity0.09x
Gross Margin96.5%
Operating Margin39.5%
Revenue Growth10.6%
Free Cash Flow$1.2B

Exelixis, Inc. operates in the Biotechnology industry, part of the Healthcare sector (United States).

Frequently Asked Questions

What is Exelixis, Inc.’s (EXEL) StockRank?
MoatMap’s StockRank for Exelixis, Inc. (EXEL) is 98/100, with a Strong Buy signal. It is a composite of Quality (89), Value (49), and Momentum (76), each scored against its sector. The composite is then ranked across MoatMap’s universe of 24,000+ stocks.
Does Exelixis, Inc. have an economic moat?
Exelixis, Inc. (EXEL) has a Quality factor score of 89/100. The Quality factor combines ROIC, Piotroski F-Score, and leverage: the financial fingerprints of a durable competitive advantage. A Quality score above 70 typically indicates a company with the characteristics of a moated business.
Is Exelixis, Inc. a buy, hold, or sell?
MoatMap’s current signal for Exelixis, Inc. (EXEL) is Strong Buy, based on a StockRank of 98/100. Signals are derived mechanically from the StockRank composite and should be one input among many; combine with your own thesis on management, competitive position, and valuation.
What sector is Exelixis, Inc. in?
Exelixis, Inc. (EXEL) operates in the Healthcare sector, specifically the Biotechnology industry (United States).