HRMY

Strong BuyFull HouseAI neutral

Harmony Biosciences Holdings, Inc. · Healthcare · United States · $2.4B cap · $38.9M/day traded

$37.54 -1.1% · close 19 Oct · scored 20 Oct

Full House: Strong business, sensible price, market agrees. The rare full house.

100
StockRank
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Quality
81
Value
73
Momentum
84

As of 20 Oct 2026, MoatMap's StockRank for Harmony Biosciences Holdings, Inc. (HRMY) is 100/100, ranked against 24,000+ stocks in 35 markets (Quality 81, Value 73, Momentum 84, each scored against its sector).

Does StockRank work? Each month we publish how every decile did, whichever way it went. See the record →

P/E (TTM)
12.2x
peers 29.2x
ROE
20.5%
peers -26.0%
D/E
0.2x
peers 0.2x
Dividend %
—
trailing yield
AI CONVICTION THESIS

Harmony Biosciences maintains strong profitability and cash conversion powered by its commercial sleep-disorder drug Wakix (pitolisant), with forward-EPS consensus expectations revising upward by 4.8%. However, the unexpected planned departure of its chief executive introduces near-term governance and strategic execution uncertainty at a crucial moment when the company must diversify its pipeline beyond a single commercial asset and manage long-term exclusivity challenges.

ABOUT HARMONY BIOSCIENCES HOLDINGS, INC.

Read

Harmony Biosciences Holdings, Inc. is a pharmaceutical company dedicated to developing and commercializing innovative therapies for patients suffering from rare neurological diseases. With its flagship product WAKIX for narcolepsy already commercialized, the company establishes a strong market position by addressing significant unmet medical needs within niche neurological disorder markets.

FINANCIAL SUMMARY (USD)

Year2022202320242025CAGRTTM2026E2027EFwd CAGR
Revenue437.9M582.0M714.7M868.5M25.6%959.9M1.0B1.2B15.9%
EPS3.072.172.562.76-3.5%3.104.005.1336.3%
Shares59.6M56.8M57.1M57.7M-3.2%58.2M———
Debt191.6M193.6M179.3M163.7M-5.1%160.2M———
Equity402.8M467.0M659.2M870.2M29.3%————
Op CF144.5M219.4M219.8M348.2M34.1%355.1M———
Inv CF-141.8M-46.4M-67.5M-39.6M—————
Fin CF6.8M-105.6M-11.0M-9.0M—————
Loading 1Y...
PRICE (1Y) · USD-10.8%
37.038.539.941.342.78 Sep29 Sep19 Oct
SMA 50SMA 200

Price checkIn an uptrendExperimental

Above its 200-day average and 14% below its 52-week high.

SwingsBumpy

Swung more than 50% of stocks we rank over the past year (41% a year).

How this is worked out

StockRank judges the business. The price check reads only the chart: it is the price side of the Momentum score, in words.

The rules: Still falling is a new 52-week low in the last two weeks, at least 25% below the high. Finding a floor is no new low since. Turning up is 20 or more trading days without a new low, at least 10% off it, and back above a rising 50-day average. In an uptrend is above the 200-day average and within 15% of the high.

In 2,112 US drawdowns since 2001, buying while the price was still falling was followed by a further 20% drop 42% of the time. Waiting for a turn like this one cut that to 33%, at about 7% higher prices and with no better returns. Part of that cut is simply not buying: 13% of falls never turned, and waiting kept those out. Among turns that were bought, 38% still fell another 20%, and 33% of turns were followed by a new low within six months. The benefit was largest in crashes such as 2008 and 2020.

What it measures: day-to-day price moves over the past year, as a yearly figure, ranked against every stock we cover. Very calm under 20% a year, Calm 20 to 30%, Average 30 to 40%, Bumpy 40 to 55%, Very bumpy above that.

What we found: across about 13,500 stocks in 34 markets (2002 to 2025), past swings were a good guide to the next year's, and bumpier stocks fell further. How much further changed too much between eras to put a number on it.

Calm is not safe: a calm stock can still slide steadily.

Rules fixed before any data was fetched. Describes the chart, not a recommendation.

Close
$37.54
RSI (14)
38.2
52-Week Range-13.7% from high
Low $25.52High $43.49

SCORE BREAKDOWN

Quality
81
ROIC
25.0%93.8
ROE
20.5%88.5
GP/Assets
56.9%90.9
Op. Margin
34.2%94.4
FCF/Assets
27.4%97.9
Piotroski
549.0
Int. Cover
18.9x70.8
D/E Ratio
0.16x55.1
Current Ratio
3.48x61.8
Value
73
P/E (TTM)
12.2x82.1
EV/EBITDA
6.7x84.6
P/FCF
6.8x90.3
P/B
2.2x54.6
P/S
2.3x62.9
Div Yield
—N/A
Momentum
84
52W High %
86%82.0
RS 6M
19%82.5
SMA 50/200
1.15x84.2
EPS Rev 4W
+4.8%95.2
EPS Rev 12W
+16.4%89.9
EPS Improve
+126%79.7
Q Growth
90%82.0

FUNDAMENTALS

Market Cap
$2.4B
P/E (Forward)
5.4x
Gross Margin
75.4%

SECTOR PEERS

Closest peers in Healthcare, ranked by industry match, size, and score similarity. Cross-listings of HRMY are excluded.

TickerCompanyMkt CapStockRankSignal
HRMYHarmony Biosciences Holdings, Inc.(you)$2.4B100Strong Buy
NRIXNurix Therapeutics, Inc.$2.5B95Strong Buy
INVAInnoviva, Inc.$1.5B93Strong Buy
RIGLRigel Pharmaceuticals, Inc.$899M98Strong Buy
ADMAADMA Biologics, Inc.$2.2B80Buy
CRMDCorMedix Inc.$599M98Strong Buy
ACADACADIA Pharmaceuticals Inc.$4.4B80Strong Buy
PBYIPuma Biotechnology, Inc.$479M98Strong Buy
ZVRAZevra Therapeutics, Inc.$672M91Strong Buy
ABUSArbutus Biopharma Corporation$961M81Strong Buy

Peer medians: ROE -26.0% · P/E 29.2x · Gross margin 63.6%

Company Deep Dive

Business segments breakdown, earnings transcript analysis, management credibility scoring, competitive landscape, and scenario modelling.

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Harmony Biosciences Holdings, Inc. (HRMY): Stock Score Summary

Harmony Biosciences Holdings, Inc. (HRMY) has a MoatMap StockRank of 100/100 based on Quality (81/100), Value (73/100), and Momentum (84/100) factor scores. The current signal is STRONG BUY. Harmony Biosciences maintains strong profitability and cash conversion powered by its commercial sleep-disorder drug Wakix (pitolisant), with forward-EPS consensus expectations revising upward by 4.8%. However, the unexpected planned departure of its chief executive introduces near-term governance and strategic execution uncertainty at a crucial moment when the company must diversify its pipeline beyond a single commercial asset and manage long-term exclusivity challenges.

Harmony Biosciences Holdings, Inc. is a pharmaceutical company dedicated to developing and commercializing innovative therapies for patients suffering from rare neurological diseases. With its flagship product WAKIX for narcolepsy already commercialized, the company establishes a strong market position by addressing significant unmet medical needs within niche neurological disorder markets.

Key Financial Metrics

Price$37.54
Market Cap$2.4B
P/E (TTM)12.24
P/E (Forward)5.42
Price/Book2.21
Return on Equity20.5%
Return on Invested Capital25.0%
Debt/Equity0.16x
Gross Margin75.4%
Operating Margin34.2%
Revenue Growth30.3%
Free Cash Flow$348M

Harmony Biosciences Holdings, Inc. operates in the Biotechnology industry, part of the Healthcare sector (United States).

Frequently Asked Questions

What is Harmony Biosciences Holdings, Inc.’s (HRMY) StockRank?
MoatMap’s StockRank for Harmony Biosciences Holdings, Inc. (HRMY) is 100/100, with a Strong Buy signal. It is a composite of Quality (81), Value (73), and Momentum (84), each scored against its sector. The composite is then ranked across MoatMap’s universe of 24,000+ stocks.
Does Harmony Biosciences Holdings, Inc. have an economic moat?
Harmony Biosciences Holdings, Inc. (HRMY) has a Quality factor score of 81/100. The Quality factor combines ROIC, Piotroski F-Score, and leverage: the financial fingerprints of a durable competitive advantage. A Quality score above 70 typically indicates a company with the characteristics of a moated business.
Is Harmony Biosciences Holdings, Inc. a buy, hold, or sell?
MoatMap’s current signal for Harmony Biosciences Holdings, Inc. (HRMY) is Strong Buy, based on a StockRank of 100/100. Signals are derived mechanically from the StockRank composite and should be one input among many; combine with your own thesis on management, competitive position, and valuation.
What sector is Harmony Biosciences Holdings, Inc. in?
Harmony Biosciences Holdings, Inc. (HRMY) operates in the Healthcare sector, specifically the Biotechnology industry (United States).